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Oligonucleotides with selectably cleavable and/or abasic sites

  • US 5,367,066 A
  • Filed: 07/24/1991
  • Issued: 11/22/1994
  • Est. Priority Date: 10/16/1984
  • Status: Expired due to Fees
First Claim
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1. A polynucleotide reagent having the structure ##STR30## wherein DNA1 is a first segment of DNA;

  • DNA2 is a second segment of DNA; and

    Rm is C1 -C16 alkylene or an oxyethylene oligomer --(CH2 CH2 O)z -- where z is an integer in the range of 1 to 16 inclusive, and Rn is selected from the group consisting of ##STR31##

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