Method and apparatus for introducing fluid material into an eye

• US 5,368,582 A
• Filed: 11/13/1992
• Issued: 11/29/1994
• Est. Priority Date: 08/10/1992
• Status: Expired due to Fees

• Current Assignee: Schepens Eye Research Institute
• Original Assignee: Schepens Eye Research Institute
• Inventors: Bertera, James H.
• Primary Examiner(s): Green, Randall L.
• Assistant Examiner(s): ZUTTARELLI, ANTHONY
• Application Number:
  US07/976,274
• Time in Patent Office: 746 Days
• Field of Search: 604/289-291, 604/294-296, 604/298, 604/300, 351/50-52, 417/207, 417/395, 128/DIG. 1, 128/DIG. 7, 128/DIG. 12, 128/DIG. 26
• US Class Current: 604/295
• CPC Class Codes: A61F 9/0008 Introducing ophthalmic products into the ocular cavity or retaining products therein putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00
• CPC Class Codes: A61F 9/0026 Ophthalmic product dispenser attachments to facilitate positioning near the eye
• CPC Class Codes: F04B 53/108 Valves characterised by the material
• CPC Class Codes: G02C 11/00 Non-optical adjuncts; Attachment thereof G02C7/16 takes precedence
• CPC Class Codes: G02C 5/001 specially adapted for particular purposes, not otherwise provided for or not fully classifiable according to technical characteristics, e.g. therapeutic glasses

Abstract

A spectacle-like device mounts a system of pump elements that can project droplets of liquid onto a wearer'"'"'s eye. A reservoir of the liquid and an electrical pump-controlling circuit are mounted on the spectacle frame for operation with the pump elements.

Claims

1. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container for liquid that is to be introduced to the eye of the person,

(B) at least one pump means having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on a spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump means being operable in response to a control signal for propelling liquid, received from said container, from said outlet and toward the eye,

(C) control means for generating said control signal and connected for applying said control signal to said pump means, said control means being arranged for mounting on the spectacle-like frame, and

(D) pump positioning means for positioning said pump means and said outlet proximate to the eye and connected in fluid communication between said container and said pump means, said positioning means being elastically displaceable upon inadvertent contact with the eye, for protecting the eye.

2. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container for liquid that is to be introduced to the eye of the person,

(B) at least one expansion-type jet pump having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump expanding fluid within said pump and being operable in response to a control signal for driving fluid, received from said container, through said fluid outlet and toward the eye, and

(C) control means for generating said control signal and connected for applying said control signal to said pump, said control means being arranged for mounting on the spectacle-like frame.

3. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container tier liquid that is to be introduced to the eye of the person,

(B) at least one pump means having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump means being operable in response to a control signal for propelling liquid, received from said container, from said outlet and toward the eye, and

(C) control means for generating said control signal and connected for applying said control signal to said pump means, said control means being arranged for mounting on the spectacle-like frame, said control means producing said control signal to eject successive droplets of liquid from said fluid outlet, said control means being arranged for generating said control signal for producing said succession of droplets with selected duration and repetition, for controlling the quantity and rate of liquid introduced to the eye, said rate being in the range of one to two thousand Hertz.

4. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container for liquid that is to be introduced to the eye of the person,

(B) at least one pump means having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump means being operable in response to a control signal for propelling liquid, received from said container, from said outlet and toward the eye, and

(C) control means for generating said control signal and connected for applying said control signal to said pump means, said control means being arranged for mounting on the spectacle-like frame, said control means producing said control signal to eject successive droplets of approximately two hundred picoliters of liquid from said fluid outlet, said control means being arranged for generating said control signal for producing said succession of droplets with selected duration and repetition, for controlling the quantity and rate of liquid introduced to the eye.

5. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container for liquid that is to be introduced to the eye of the person,

(B) at least one pump means having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump means being operable in response to a control signal for propelling liquid, received from said container, from said outlet and toward the eye, and

(C) control means for generating said control signal and connected for applying said control signal to said pump means, said control means being arranged for mounting on the spectacle-like frame, said control means producing said control signal to eject successive droplets of liquid from said fluid outlet, said control means being arranged for generating said control signal for producing said succession of droplets with selected duration and repetition, for controlling the quantity and rate of liquid introduced to the eye, said control means being arranged for producing said control signal intermittently and wherein said rate is approximately one to two thousand Hertz.

6. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container for liquid that is to be introduced to the eye of the person,

(B) multiple pump means circumferentially disposed around at least one lens aperture of the spectacle-like frame, each of said pump means having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump means being operable in response to a control signal for propelling liquid, received from said container, from said outlet and toward the eye, and

(C) control means for generating said control signal and connected for applying said control signal to said pump means, said control means being arranged for mounting on the spectacle-like frame.

7. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container for liquid that is to be introduced to the eye of the person,

(B) at least one pump means having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump means comprising at least one piezoelectric crystal for creating hydraulic pressure inside said container and being operable in response to a control signal for presurizing said container to propel liquid through said outlet and toward the eye, and

(C) control means for generating said control signal and being connected for applying said control signal to said pump means.

8. Apparatus for the topical introduction of liquid to the eye of a person wearing spectacle-like frame, said apparatus comprising

(A) a pressurized vessel containing liquid that is to be introduced to the eye of the person,

(B) at least one valve means having a fluid outlet and coupled with said vessel to control liquid therefrom and arranged for mounting with said vessel on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said valve means comprising a micro-valve having a piezoelectric crystal actuator and being operable in response to a control signal for releasing liquid from said pressurized vessel to eject liquid through said outlet and toward the eye, and

(C) control means for generating said control signal and being connected for applying said control signal to said pump means.

9. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a pressurized vessel containing liquid that is to be introduced to the eye of the person,

(B) at least one valve means having a fluid outlet and coupled with said vessel to control liquid therefrom and arranged for mounting with said vessel on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said valve means comprising a shape-memory alloy for creating a micro-valve and being operable in response to a control signal for releasing liquid from said pressurized vessel to eject liquid through said outlet and toward the eye, and

(C) control means for generating said control signal and being connected for applying said control signal to said pump means.

10. Apparatus according to claim 9 wherein said shape memory alloy is TiNi.

11. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container for liquid that is to be introduced to the eye of the person,

(B) at least one pump means having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump means having heating means and being operable in response to a control signal for thermally expanding fluid and for expelling liquid, received from said container, through said fluid outlet and toward the eye, and

(C) control means for generating said control signal and connected for applying said control signal to said pump means, said control means being arranged for mounting on the spectacle-like frame.

12. Apparatus according to claim 11 wherein said heating means includes a thin film resistor element.

13. Apparatus according to claim 11 further comprising means for separating liquid being discharged from said fluid outlet from the thermally expanded fluid.

14. Apparatus according to claim 11 wherein said heating means includes a laser source for delivering thermal energy to said fluid.

15. Apparatus according to claim 11 wherein said heating means includes a laser source and an absorbing element, said laser source being arranged for heating said absorbing element and said absorbing element is arranged for heating fluid by conduction.

16. Apparatus for the topical introduction of liquid to the eye of a person wearing a spectacle-like frame, said apparatus comprising

(A) a container for liquid that is to be introduced to the eye of the person,

(B) at least one pump means having a fluid outlet and coupled with said container to receive liquid therefrom and arranged for mounting with said container on the spectacle-like frame with said outlet directed toward and spaced away from the eye,

said pump means including a thermal expansion-type jet pump and being operable in response to a control signal for thermally expanding fluid and for expelling liquid, received from said container, through said fluid outlet and toward the eye, said expansion-type jet pump having diaphragm means disposed between the thermally expanded fluid and said fluid outlet, and

(C) control means for generating said control signal and connected for applying said control signal to said pump means, said control means being arranged for mounting on the spectacle-like frame.

17. Apparatus according to claim 16 in which said diaphragm means forms a first pump chamber in which fluid is expanded for pumping action and forms a second pump chamber contiguous with said first chamber and from which fluid is discharged in response to said pumping action.

18. Apparatus according to claim 17

in which said container is coupled for applying liquid therein to said second pump chamber, and

further comprising a second container for fluid and coupled with said first pump chamber.