Heated balloon catheters

• US 5,368,591 A
• Filed: 11/23/1992
• Issued: 11/29/1994
• Est. Priority Date: 10/28/1988
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Prutech Research and Development Partnership
• Inventors: Lennox, Charles D., Noddin, Richard A., Sahatjian, Ronald
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US07/981,006
• Time in Patent Office: 736 Days
• Field of Search: 128/399-402, 128/784-786, 128/804, 606/27-31
• US Class Current: 606/27
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 18/08 by means of electrically-heated probes
• CPC Class Codes: A61B 18/082 Probes or electrodes therefor
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/00088 using thermistors
• CPC Class Codes: A61B 2017/00132 Setting operation time of a device A61B2017/00123 takes precedence
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2017/22062 to be filled with liquid
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 2018/00559 Female reproductive organs
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/044 the surgical action being effected by a circulating hot fluid

Abstract

Device and method for heating tissue, the device having a catheter shaft for insertion into a patient'"'"'s body, a chamber formed by a collapsible balloon mounted on the catheter shaft and filled with an electrically conductive fluid, two or more electrical contacts enclosed within the chamber, a power supply for applying an electrical potential to the contacts, and a two or more conductors for connecting each of the contacts to the power supply. The fluid is heated on the basis of I² R losses by a radio frequency electric current flowing between the electrodes, and the fluid in turn heats the surrounding tissue by heat transfer through the wall of the chamber. According to the method, the apparatus is inserted into the patient'"'"'s body, the chamber is filled with an electrically conductive fluid, and an electrical potential is applied to the contacts. The apparatus functions as a temperature source. A thermister sensor in the balloon or in contact with tissue responds to the heating effect to control the application of the current. Advantageously, by periodic sensing of temperature, and application of controlled rf power, a preset constant temperature is maintained at the selected sensing point, either at the internal body site or the liquid within the balloon. In this way carefully controlled therapy can be conducted at constant temperature.

Claims

1. A balloon catheter device for heating tissue, comprising:

a catheter shaft constructed for insertion into a patient'"'"'s body,

a fluid-inflatable balloon mounted on said shaft, said balloon defining an interior inflation chamber and an exterior surface for engagement with body tissue to be heated, said interior inflation chamber of said balloon being associated with a lumen extending through said shaft for introduction of inflation fluid from a source outside said body to permit said chamber to be filled with said inflation fluid after placement of said balloon catheter in said body,

an electrically conductive, resistive pathway located in said interior inflation chamber of said balloon, arranged for heating said exterior surface of said balloon from within said balloon by passage of RF electrical current through said conductive, resistive pathway, said balloon catheter device being constructed to prevent said electrical current from reaching said exterior surface of said balloon,

a plurality of electrical conductors for conducting RF electric current at a frequency above about 100 kilohertz, said plurality of conductors extending along the length of said catheter shaft for introducing current from an RF current source to said conductive, resistive pathway, and

a sensor constructed to provide a feedback signal to permit delivery of RF current to said pathway to be controlled so that the temperature of said exterior surface of said balloon can in turn be controlled.

2. The balloon catheter device of claim 1 wherein said plurality of electrical conductors extend into the space surrounded by said balloon to apply said RF current to said conductive, resistive pathway.

3. The balloon catheter device of claim 1 wherein said balloon is formed of polyethylene terephthalate.

4. The balloon catheter device of claim 1 wherein said catheter device is an angioplasty catheter and said balloon is an angioplasty balloon sized and constructed for inflation to pressures sufficient to dilate a stenosed blood vessel.

5. The balloon catheter device of claim 1 wherein the temperature of said exterior surface of said balloon is a function of the temperature of heated inflation fluid in thermal contact with the wall of said balloon.

6. The balloon catheter of claim 1 wherein said RF frequency is less than about 1 megahertz.

7. A method for heating tissue, comprising the steps of:

providing a catheter device comprising a catheter shaft constructed for insertion into a patient'"'"'s body, a balloon mounted on said shaft, said balloon defining an interior inflation chamber and an exterior surface, an electrically conductive, resistive pathway located in said interior inflation chamber of said balloon, a plurality of electrical conductors extending along the length of said catheter shaft to said conductive, resistive pathway, and a sensor constructed to provide a feedback signal to permit delivery of RF current to said pathway to be controlled,

placing said balloon catheter in said body,

inflating said balloon by introducing inflation fluid from a source outside said body through a lumen extending through said shaft to fill said interior inflation chamber,

engaging body tissue with said exterior surface of said balloon,

heating said exterior surface of said balloon from within said balloon by passing RF electrical current at a frequency above about 100 kilohertz from an RF current source through said electrical conductors and through said conductive, resistive pathway, said electrical current being prevented from reaching said exterior surface of said balloon, and

providing a feedback signal from said sensor to permit delivery of RF current to said pathway to be controlled so that the temperature of said exterior surface of said balloon can in turn be controlled.

8. A method in accordance with claim 7, wherein

said step of placing said balloon catheter in said body comprises positioning said chamber in the vicinity of undesired cells, and

said step of heating said exterior surface of said balloon comprises heating with an intensity and duration sufficient to destroy said undesired cells.

9. A hyperthermic treatment catheter having a distal portion sized to enter a selected passage of a body and constructed and arranged upon actuation to destroy undesired cells lying in a thermally conductive relationship to said distal portion of said catheter, comprising:

a catheter shaft constructed for insertion into a patient'"'"'s body,

a fluid-inflatable balloon mounted on said shaft, said balloon defining an interior inflation chamber and an exterior surface for engagement with body tissue to be heated, said interior inflation chamber of said balloon being associated with a lumen extending through said shaft for introduction of inflation fluid from a source outside said body to permit said chamber to be filled with said inflation fluid after placement of said balloon catheter in said body,

an electrically conductive, resistive pathway located in said interior inflation chamber of said balloon, arranged for heating said exterior surface of said balloon from within said balloon by passage of RF electrical current through said conductive, resistive pathway, said balloon catheter device being constructed to prevent said electrical current from reaching said exterior surface of said balloon while said exterior surface of said balloon is heated with an intensity and duration sufficient to destroy said undesired cells,

a plurality of electrical conductors for conducting RF electric current at a frequency above about 100 kilohertz, said plurality of conductors extending along the length of said catheter shaft for introducing current from an RF current source to said conductive, resistive pathway, and

a sensor constructed to provide a feedback signal to permit delivery of RF current to said pathway to be controlled so that the temperature of said exterior surface of said balloon can in turn be controlled.