Apparatus for reducing intraocular pressure

• US 5,372,577 A
• Filed: 02/18/1993
• Issued: 12/13/1994
• Est. Priority Date: 04/11/1988
• Status: Expired due to Fees

• Current Assignee: Bruce A. Ungerleider
• Original Assignee: Bruce A. Ungerleider
• Inventors: Ungerleider, Bruce A.
• Primary Examiner(s): Hafer, Robert A.
• Assistant Examiner(s): RIMELL, SAMUEL G
• Application Number:
  US08/020,253
• Time in Patent Office: 663 Days
• Field of Search: 604/8, 604/9, 604/10, 604/294, 604/284, 604/264, 604/11, 623/4, 606/107
• US Class Current: 604/8
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

A method is described herein for implanting in the cornea and limbal area a device partially embedded and partially extending anteriorly, a preferred embodiment comprising one or more loops of small sized porous ropes, cords, bands or hollow tubes, which device has one end or section thereof extending beyond the exterior surface of the cornea and limbal areas so that aqueous humor may be exited from the anterior chamber in the eye to relieve intraocular pressure and thereby avoid or reduce the effects of glaucoma.

Claims

1. An apparatus for relieving the fluid pressure in the human eye associated with glaucoma, comprising:

a strand defining an outer surface with said outer surface of said strand defining a first end, a middle and a second end;

said strand being formed from an open celled biocompatible material and defining a plurality of pores defined therein with said plurality of pores communicating with adjacent pores for enabling liquid entering one portion of said outer surface of said strand to pass to other portions of said outer surface of said strand;

said plurality of pores being sufficiently large for enabling the flow of aqueous humor therethrough and concomitantly sufficiently small to inhibit the ingress of pathogens therein;

said strand being flexible and sufficiently rigid to maintain the size of said plurality of pores;

said strand being implantable beneath the superficial layers of the cornea of the eye with the middle portion of said strand being disposed within the anterior chamber of the eye and straddling the limbus of the eye; and

said first and second ends of said strand extending external to the eye and on the ocular surface of the eye for permitting aqueous humor fluid in the anterior chamber of the eye to pass from said middle portion of said strand through said plurality of pores in said strand and pass onto the ocular surface of the eye for relieving the fluid pressure in the eye associated with glaucoma; and

means for connecting said first end of said strand directly to said second end of said strand external to the eye for maintaining the position of said strand within the eye, wherein said first and second ends are in direct contact.

2. An apparatus for relieving the fluid pressure in the human eye associated with glaucoma, comprising:

a strand defining an outer surface with said outer surface of said strand defining a first end, a middle and a second end;

said strand being formed from an open celled biocompatible material having a plurality of pores defined therein with said plurality of pores communicating with adjacent pores for enabling liquid entering one portion of said outer surface of said strand to pass to other portions of said outer surface of said strand;

said plurality of pores being sufficiently large for enabling the flow of aqueous humor therethrough and concomitantly sufficiently small to inhibit the ingress of pathogens therein;

said strand being flexible and sufficiently rigid to maintain the size of said plurality of pores;

said strand being implantable beneath the superficial layers of the cornea of the eye with the middle portion of said strand being disposed within the anterior chamber of the eye and straddling the limbus of the eye;

said first and second ends of said strand extending external to the eye and on the ocular surface of the eye for forming a loop with said strand for permitting aqueous humor fluid in the anterior chamber of the eye to pass from said middle portion of said strand through said plurality of pores in said strand and pass onto said ocular surface of the eye for relieving the fluid pressure in the eye associated with glaucoma; and

means for joining said first end of said strand directly to said second end of said strand external to the eye for maintaining the position of said strand within the eye wherein said first and second ends are in direct contact.

3. An apparatus for introducing a drug from the ocular surface of the eye into anterior chamber of the eye, comprising:

a strand defining an outer surface with said outer surface of said strand defining a first end, a middle and a second end;

said strand being formed from an open celled biocompatible material and defining a plurality of pores therein with said plurality of pores communicating with adjacent pores for enabling liquid entering one portion of said outer surface of said strand to pass to other portions of said outer surface of said strand;

said plurality of pores being sufficiently large for enabling the flow of aqueous humor therethrough and concomitantly sufficiently small to inhibit the ingress of pathogens therein;

said strand being flexible and sufficiently rigid to maintain the size of said plurality of pores;

said strand being implantable beneath the superficial layers of the cornea of the eye with the middle portion of said strand being disposed within the anterior chamber of the eye and straddling the limbus of the eye; and

said first and second ends of said strand extending external to the eye and on the ocular surface of the eye for permitting aqueous humor fluid in the anterior chamber of the eye to pass from the middle portion of said strand through said plurality of pores in said strand and pass onto the ocular surface of the eye for relieving the fluid pressure in the eye associated with glaucoma and;

means for connecting said first end of said strand directly to said second end of said strand external to the eye for maintaining the position of the strand within the eye and wherein said first and second ends are in direct contact, and;

a drug disposed on the ocular surface of the eye for absorption by said plurality of pores to migrate through said plurality of pores in said body and to pass into the anterior chamber of the eye.

4. An apparatus for transferring aqueous humor from the anterior chamber of the eye onto the ocular surface, comprising:

a body defining an outer surface;

said body having an inner enlarged portion and an outer enlarged portion with a central portion disposed therebetween;

said inner enlarged portion and said outer enlarged portion being substantially enlarged relative to said central portion with said inner and outer enlarged portions extending substantially perpendicular to said central portion, said inner enlarged portion defining cylindrical feet and said outer enlarged portion defining a concave surface;

said body having a plurality of pores defined therein with said plurality of pores communicating with adjacent pores for enabling liquid entering one portion of said outer surface of said body to pass to other portions of said outer surface of said body;

said plurality of pores being sufficiently large for enabling the flow of aqueous humor therethrough and concomitantly sufficiently small to inhibit the ingress of pathogens therein;

said body being flexible and sufficiently rigid to maintain the size of said plurality of pores; and

said inner enlarged portion of said body member being implanted beneath the superficial layers of the cornea of the eye and in communication with the anterior chamber and straddling the limbus of the eye and with said outer enlarged portion being disposed proximate to the ocular surface of the eye for permitting aqueous humor fluid in the anterior chamber of the eye to pass through said plurality of pores in said body and pass onto the ocular surface of the eye.

5. An apparatus for transferring aqueous humor from the anterior chamber of the eye onto the ocular surface, comprising:

a body defining an outer surface;

said body having an inner enlarged portion and an outer enlarged portion with a central portion disposed therebetween;

said central portion of said body being substantially cylindrical;

said inner enlarged portion and said outer enlarged portion being substantially enlarged relative to said central portion with said inner and outer enlarged portions extending substantially perpendicular to said central portion, said inner enlarged portion defining cylindrical feet and said outer enlarged portion defining a concave surface;

said body having a plurality of pores defined therein with said plurality of pores communicating with adjacent pores for enabling liquid entering one portion of said outer surface of said body to pass to other portions of said outer surface of said body;

said plurality of pores being sufficiently large for enabling the flow of aqueous humor therethrough and concomitantly sufficiently small to inhibit the ingress of pathogens therein;

said body being flexible and sufficiently rigid to maintain the size of said plurality of pores; and

said inner enlarged portion of said body member being implanted beneath the superficial layers of the cornea of the eye and in communication with the anterior chamber and straddling the limbus of the eye and with said outer enlarged portion being disposed proximate to the ocular surface of the eye for permitting aqueous humor fluid in the anterior chamber of the eye to pass through said plurality of pores in said body and pass onto the ocular surface of the eye.

6. An apparatus for introducing a drug into an anterior chamber of the eye, comprising:

a strand defining an outer surface with said outer surface of said strand defining a first end, a middle and a second end;

said strand being formed from an open celled biocompatible material and defining a plurality of pores therein with said plurality of pores communicating with adjacent pores for enabling liquid entering one portion of said outer surface of said strand to pass to other portions of said outer surface of said strand;

said plurality of pores being sufficiently large for enabling the flow of aqueous humor therethrough and concomitantly sufficiently small to inhibit the ingress of pathogens therein;

said strand being flexible and sufficiently rigid to maintain the size of said plurality of pores;

said strand being implantable beneath the superficial layers of the cornea of the eye with the middle portion of said strand being disposed within the anterior chamber of the eye and straddling the limbus of the eye; and

said first and second ends of said strand extending external to the eye and on the ocular surface of the eye for permitting aqueous humor fluid in the anterior chamber of the eye to pass from the middle portion of said strand through said plurality of pores in said strand and pass onto the ocular surface of the eye for reliving the fluid pressure in the eye associated with glaucoma and;

means for connecting said first end of said strand directly to said second end of said strand external to the eye for maintaining the position of the strand within the eye and wherein said first and second ends are in direct contact, and;

a drug located in said plurality of pores of said body.