Methods for benefitting polymers

• US 5,376,737 A
• Filed: 10/09/1992
• Issued: 12/27/1994
• Est. Priority Date: 04/25/1991
• Status: Expired due to Term

• Current Assignee: Abbott Medical Optics Incorporated (Johnson & Johnson)
• Original Assignee: Allergan Incorporated (Abbvie Incorporated)
• Inventors: Yang, Shih-Liang S.
• Primary Examiner(s): Hoke, Veronica P.
• Application Number:
  US07/959,394
• Time in Patent Office: 809 Days
• Field of Search: 525/477, 525/478
• US Class Current: 525/477
• CPC Class Codes: C07F 7/0838 Compounds with one or more Si-O-Si sequences compounds with a ring containing only alternating Si and O atoms, i.e. cyclosilanes C07F7/21
• CPC Class Codes: C07F 7/0896 Compounds with a Si-H linkage
• CPC Class Codes: C08F 299/08 from polysiloxanes
• CPC Class Codes: C08F 8/30 Introducing nitrogen atoms or nitrogen-containing groups
• CPC Class Codes: C08G 77/045 containing less than 25 silicon atoms
• CPC Class Codes: C08G 77/12 containing silicon bound to hydrogen C08G77/045 takes precedence
• CPC Class Codes: C08G 77/18 to alkoxy or aryloxy groups
• CPC Class Codes: C08G 77/20 containing silicon bound to unsaturated aliphatic groups C08G77/045 takes precedence
• CPC Class Codes: C08G 77/24 halogen-containing groups
• CPC Class Codes: C08G 77/70 Siloxanes defined by use of the MDTQ nomenclature
• CPC Class Codes: C08K 5/5477 containing nitrogen in a heterocyclic ring
• CPC Class Codes: C08L 2666/44 Silicon-containing compounds
• CPC Class Codes: C08L 83/00 Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: G02B 1/043 Contact lenses

Abstract

Methods for incorporating beneficial components into polymeric materials are disclosed. In one embodiment, the method comprises introducing a reactable UV light absorbing component into a cross-linked and/or solid polymeric material containing reactable groups, and subjecting the reactable UV light absorbing component to conditions effective to chemically react the reactable UV light absorbing component with the reactable groups of the solid polymeric material.

Claims

1. A method for incorporating a UV light absorbing constituent into a polymer material which comprises:

introducing a reactable UV light absorbing component including a functional group selected from the class consisting of functional silicon-bonded hydride groups and functional ethylenically unsaturated groups into a polysiloxane polymer which is solid and cross-linked and contains reactable groups selected from the class consisting of reactable silicon-bonded hydride groups and reactable ethylenically unsaturated groups; and

, thereafter,

subjecting said reactable UV light absorbing component to conditions effective to chemically react said reactable UV light absorbing component with said reactable groups of said polysiloxane polymer and form a polymer material to which is covalently bonded an effective amount of a UV light absorbing constituent derived from said reactable UV light absorbing component.

2. The method of claim 1 wherein said introducing and subjecting are effective to distribute said UV light absorbing constituent substantially uniformly throughout said polymer material.

3. The method of claim 1 wherein said reactable UV light absorbing component is present in a liquid during at least a portion of said introducing.

4. The method of claim 1 wherein said reactable groups are reactable silicon-bonded hydride groups and said reactable UV light absorbing component includes a functional ethylenically unsaturated group.

5. The method of claim 1 wherein said reactable UV light absorbing component includes at least one siloxane moiety effective to enhance the compatibility of said reactable UV light absorbing component with said silicone polymer relative to a substantially identical reactable UV light absorbing component without at least one siloxane moiety.

6. The method of claim 1 wherein said reactable UV light absorbing component is selected from benzotriazole derivatives and mixtures thereof.

7. The method of claim 1 wherein said subjecting is substantially ineffective to increase or decrease the degree of polymerization or the degree of cross-linking of said polysiloxane polymer.

8. The method of claim 1 wherein said polysiloxane polymer is an optically clear, platinum-catalyzed, addition cure, cross-linked polysiloxane polymer containing reactable silicon-bonded hydride groups, and said reactable UV light absorbing component is a benzotriazole derivative including a functional vinyl group.

9. The method of claim 8 which further comprises forming said polymer material into a lens.

10. A method for incorporating a UV light absorbing component into a polymeric material which comprises:

contacting a reactable UV light absorbing component including a functional group selected from the class consisting of functional silicon-bonded hydride groups and functional ethylenically unsaturated groups with a polysiloxane polymer which is solid and cross-linked and which contains reactable groups selected from the class consisting of reactable silicon-bonded hydride groups and reactable ethylenically unsaturated groups at conditions effective to chemically react said reactable UV light absorbing component with the reactable groups of said polysiloxane polymer.

11. A method for incorporating a beneficial constituent into a polymer material which comprises:

introducing a reactable beneficial component including a functional group selected from the class consisting of functional silicon-bonded hydride groups and functional ethylenically unsaturated groups into a polymeric material which is a cross-linked and solid polysiloxane including reactable groups selected from the class consisting of reactable silicon-bonded hydride groups and reactable ethylenically unsaturated groups; and

, thereafter,

subjecting said reactable beneficial component to conditions effective to chemically react said reactable beneficial component with said reactable groups of said polymeric material, thereby forming a polymer material to which is covalently bonded a beneficial constituent derived from said reactable beneficial component in an amount effective to provide a benefit to said polymer material.

12. The method of claim 11 wherein said introducing and subjecting are effective to distribute said beneficial constituent substantially uniformly throughout said polymer material.

13. The method of claim 11 wherein said reactable groups are silicon-bonded hydride groups.

14. The method of claim 11 wherein said conditions are ineffective to increase or decrease the degree of polymerization or the degree of cross-linking of said polysiloxane.

15. The method of claim 11 wherein said polymer material is optically clear, and which method further comprises forming said polymer material into a foldable intraocular lens.

16. The method of claim 11 wherein said beneficial constituent is effective to provide said polymer material with reduced reactivity relative to the reactivity of said polymeric material.

17. A method for incorporating a beneficial constituent into a polymer material which comprises:

introducing a reactable beneficial component including a functional group selected from the class consisting of functional silicon-bonded hydride groups and functional ethylenically unsaturated groups into a polymeric material which is a solid and cross-linked polysiloxane containing reactable groups selected from the class consisting of reactable silicon-bonded hydride groups and reactable ethylenically unsaturated groups; and

, thereafter,

subjecting said reactable beneficial component to conditions effective to chemically react said reactable beneficial component with said reactable groups of said polymeric material, thereby forming a polymer material to which is covalently bonded a beneficial constituent derived from said reactable beneficial component in an amount effective to provide a benefit to said polymer material, provided that said subjecting is substantially ineffective to increase or decrease the degree of polymerization or the degree of cross-linking of said polymeric material, and said polymer material is utilized without further substantial polymerization or cross-linking.