Sensor for measuring the amount of a component in solution
First Claim
1. A sensor to be connected to a device for processing an electric signal provided by the sensor and representative of an amount of a component to be measured in a solution, said sensor comprising at least one measuring electrode and one reference electrode insulated from one another,said electrodes defining an area to receive said solution and comprising respective areas defining electrical contacts to be connected to the device for processing the signal,said measuring electrode comprising at least one current collector electrically connected to one of the electrical contacts and coated with a mixture comprising glucose oxidase as an oxidation-reduction enzyme specific to said component and at least one mediator means for transferring electrons between said enzyme and said current collector,and said mediator means comprising tris(4,4'"'"'-dimethoxy-2,2'"'"'-bipyridine) osmium or bis(4,4'"'"'-dimethoxy-2,2'"'"'-bipyridine)mono(4,4'"'"'-dimethyl-2,2'"'"'-bipyridine) osmium.
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Accused Products
Abstract
A sensor for measuring the amount of a component in solution is disclosed. The sensor has a measuring electrode with at least one current collector, electrically connected to one of the electrical contacts and coated with a mixture comprising at least one oxidation-reduction enzyme specific to said component and at least one mediator transferring the electrons between said enzyme and said current collector wherein the mediator is a transition metal complex with at least one bipyridine, terpyridine or phenanthroline ligand substituted by at least one electron donor group. This sensor is particularly useful in the detection of glucose.
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Citations
14 Claims
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1. A sensor to be connected to a device for processing an electric signal provided by the sensor and representative of an amount of a component to be measured in a solution, said sensor comprising at least one measuring electrode and one reference electrode insulated from one another,
said electrodes defining an area to receive said solution and comprising respective areas defining electrical contacts to be connected to the device for processing the signal, said measuring electrode comprising at least one current collector electrically connected to one of the electrical contacts and coated with a mixture comprising glucose oxidase as an oxidation-reduction enzyme specific to said component and at least one mediator means for transferring electrons between said enzyme and said current collector, and said mediator means comprising tris(4,4'"'"'-dimethoxy-2,2'"'"'-bipyridine) osmium or bis(4,4'"'"'-dimethoxy-2,2'"'"'-bipyridine)mono(4,4'"'"'-dimethyl-2,2'"'"'-bipyridine) osmium.
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8. A sensor to be connected to a device for processing an electric signal provided by the sensor and representative of an amount of a component to be measured in a solution, said sensor comprising at least one measuring electrode and one reference electrode insulated from one another;
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said electrodes defining an area to receive said solution and comprising respective areas defining electrical contacts to be connected to the device for processing the signal; said measuring electrode comprising at least one current collector electrically connected to one of the electrical contacts and coated with a mixture comprising an active conducting material, glucose oxidase as an oxidation-reduction enzyme specific to said component, at least one mediator means for transferring electrons between said enzyme and said current collector and between said enzyme and said active conducting material, and an additive forming an immobilization network of said mixture; and said mediator means comprising tris(4,4'"'"'-dimethoxy-2,2'"'"'-bipyridine) osmium or bis(4,4'"'"'-dimethoxy-2,2'"'"'- bipyridine)mono(4,4'"'"'-dimethyl-2,2'"'"'-bipyridine) osmium. - View Dependent Claims (9, 10, 11, 12, 13, 14)
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Specification