Method for intra-operative myocardial device revascularization

• US 5,380,316 A
• Filed: 06/16/1993
• Issued: 01/10/1995
• Est. Priority Date: 12/18/1990
• Status: Expired due to Term

• Current Assignee: Eclipse Surgical Technologies, Inc. (Cryolife Incorporated)
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Aita, Michael, Mirhoseini, Mahmood, Simpson, Carl J., Cayton, Mary, Guscott, Brian
• Primary Examiner(s): ASCHENBRENNER, PETER
• Application Number:
  US08/079,699
• Time in Patent Office: 573 Days
• Field of Search: 606/2, 606/3, 606/7, 606/13, 606/14, 606/15, 606/16, 606/17, 128/397, 128/398
• US Class Current: 606/7
• CPC Class Codes: A61B 18/245 for removing obstructions in blood vessels or calculi
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61B 2018/2266 with a lens, e.g. ball tipped

Abstract

The method for intra-operative myocardial revascularization of a human heart includes a inserting a portion of an elongated flexible lasing apparatus into the chest cavity of a patient, and lasing channels from the epicardium through the myocardium of the heart, without mechanical tearing of the heart tissue. The apparatus is guided to an area exterior to a ventricle of the patient'"'"'s heart, and the distal end of the optical fiber apparatus is directed to an area of interest where the exterior wall of the heart is irradiated with laser energy to form a channel through the myocardium.

Claims

1. A method of revascularizing a desired portion of a patient'"'"'s myocardium, comprising the steps of:

providing an elongated flexible optical fiber system having proximal and distal ends;

guiding a distal portion of the elongate flexible optical fiber system within the patient'"'"'s chest cavity and urging the distal end thereof into contact with an exterior portion of the patient'"'"'s epicardium which is extensive with the desired portion of the myocardium to be revascularized; and

transmitting laser energy from a remote source thereof through the optical fiber system to the distal end of said optical fiber system and directing transmitted laser energy emitted from the distal end thereof in a beam onto the portion of the patient'"'"'s epicardium in contact therewith with sufficient energy and for a sufficient length of time to form a revascularizing channel through the epicardium, the myocardium and the endocardium having transverse dimensions at least the same as the distal end of the optical fiber system while urging the distal end of the optical fiber system against tissue thereof.

2. The method of claim 1 further including the steps of monitoring the systole and diastole of the patient'"'"'s heart, and performing said step of directing laser energy onto the epicardium of the patient'"'"'s heart with transmitted laser energy in a plurality of pulses during systole of the heart.

3. The method of claim 1, wherein a portion of said elongated flexible lasing apparatus is capable of being shaped and supported in a desired configuration, and wherein said guiding of said elongated flexible lasing apparatus further comprises shaping said portion into a desired configuration.

8. The method of claim 1 wherein a lens having a diameter of not greater than about 2 mm is provided on the distal end of the optical fiber system and wherein laser energy transmitted through the optical fiber system is directed through the lens onto the epicardium layer of the patient'"'"'s heart to form a revascularizing channel therein having a diameter of about 1.5 to about 2 mm.

10. The method of claim 1 wherein the laser energy is transmitted through the optical fiber in a plurality of pulses during the patient'"'"'s systole.

11. The method of claim 1 wherein the laser energy is at a first energy level when passing thorugh the patient'"'"'s epicardium and at a second energy level lower than the first when passing through the patient'"'"'s myocardium.

12. The method of claim 1 wherein the distal portion of the optical fiber system is passed into the patient'"'"'s chest cavity through a small incision in the patient'"'"'s chest.

13. The method of claim 1 wherein a lens having a diameter of not greater than about 2 mm is provided on the distal end of the optical fiber system and wherein laser energy transmitted through the optical fiber system is directed through the lens to facilitate advancement of the optical fiber through the revascularizing channel as it is formed.

14. The method of claim 13 wherein the revascularization channel has a diameter not more than about 0.5 mm greater than the lens.

4. A method of increasing the flow of blood within a patient'"'"'s heart by forming at least one channel through an exterior wall of the patient'"'"'s heart into a heart chamber defined by the wall, comprising the steps of:

directing a distal portion of an elongated flexible lasing system having a distal end into the patient'"'"'s chest cavity;

guiding the distal end of the flexible lasing system within the patient'"'"'s chest cavity to engage an exterior area of the wall of the patient'"'"'s heart in which increased blood flow is desired; and

directing laser energy in a beam from the distal end of said flexible lasing system in a plurality of pulses during individual heart beats to create a revascularizing channel in the wall of the patient'"'"'s heart and guiding the distal end of the flexible lasing system in the channel created while creating the channel until the channel extends into and is in communication with heart chamber defined by the wall.

5. The method of claim 4, wherein a lens having a diameter of not greater than about 2 mm is provided on the distal end of the flexible lasing system and wherein laser energy transmitted through the flexible lasing system is focused into a beam to form the channel.

6. The method of claim 4, further including the steps of monitoring the systcle and diastole of the heart, and performing said step of directing said laser energy emission on the exterior wall of the heart in a plurality of pulses during systole of the heart.

7. The method of claim 5 wherein a portion of said elongated flexible lasing system is capable of being shaped and supported in a desired configuration, and wherein the guiding of said elongated flexible lasing apparatus further comprises shaping said portion into a desired configuration.

9. The method of claim 5 wherein a lens having a diameter of not greater than about 2 mm is provided on the distal end of the optical fiber system and wherein laser energy transmitted through the optical fiber system is directed through lens onto the wall of the patient'"'"'s heart to form a revascularization channel therein having a diameter of about 1.5 to about 2 mm.

15. The method of claim 5 wherein the revascularization channel has a diameter not more than about 0.5 mm greater than the lens mounted on the distal end of the flexible lasing system.