Apparatus for the transfer of a defined specimen quantity from an outer space into a test chamber

• US 5,384,095 A
• Filed: 01/28/1993
• Issued: 01/24/1995
• Est. Priority Date: 08/08/1990
• Status: Expired due to Fees

• Current Assignee: Andos Technik Fur Die Medizin GmbH
• Original Assignee: Andos Technik Fur Die Medizin GmbH
• Inventors: Griefan, Joachim, Maurer, Jorg P., Golz, Horst
• Primary Examiner(s): Housel, James C.
• Assistant Examiner(s): Le, Long V.
• Application Number:
  US08/011,848
• Time in Patent Office: 726 Days
• Field of Search: 422/99, 422/100, 422/63, 222/362, 73/863.71, 73/863.73, 73/863.81, 73/863.85, 73/863.86, 436/174, 436/180
• US Class Current: 422/501
• CPC Class Codes: G01F 11/14 wherein the measuring chamber reciprocates
• CPC Class Codes: G01N 35/1097 characterised by the valves valves in general F16K
• CPC Class Codes: Y10T 436/25 including sample preparation
• CPC Class Codes: Y10T 436/2575 Volumetric liquid transfer

Abstract

An apparatus for the transfer of a very small defined quantity of a specimen from an outer space to a reagent contained in a test chamber via a transfer slide mechanism that is displaceably disposed in a housing bore embodied as a sealing seat and that is provided with a channel that establishes the specimen quantity and is embodied as a capillary tube. The channel is adapted to be moved out of the filling position, where it is disposed in front of a receiving opening that communicates with the outer space in order to fill the channel with the specimen quantity, and into a test position in such a way that at the same time the receiving open is closed by the slide mechanism and the specimen quantity is introduced into the test chamber in order to empty the channel. The housing bore has an opening for communicating with the test chamber and is provided at this opening with a sealing lip that engages the slide mechanism in a sealing and wiping manner only when the slide mechanism is moved out of the filling position thereof and into the test position.

Claims

1. In an apparatus for transferring a defined quantity of a specimen from an outer space to a reagent contained in a test chamber by a transfer slide mechanism that is displaceably disposed in a bore of a housing, said bore serving as a sealing seat, with said slide mechanism being provided with channel means that establishes the specimen quantity and is in the form of a capillary tube, whereby said transfer slide mechanism and said channel means are movable out of a filling position, where said channel means communicates with a receiving opening that in turn communicates with said outer space in order to fill said channel means with said specimen quantity, and into a test position wherein said receiving opening is closed by said transfer slide mechanism and said specimen quantity is introduced into said test chamber in order to empty said channel means, the improvement wherein:

said housing bore has an opening for communicating with said test chamber and said housing including at said housing bore opening a sealing lip that engages said transfer slide mechanism in a sealing and wiping manner when said transfer slide mechanism is moved out of said filling position thereof and into said test position, whereby in said filling position of said transfer slide mechanism, the inside diameter of said sealing lip is less than the outer diameter of said transfer slide mechanism in the vicinity of said channel means thereof and is also less than the inside diameter of said housing bore in the vicinity of said receiving opening of said housing.

2. An apparatus according to claim 1, in which said transfer slide mechanism, between said channel means and an end of said transfer slide mechanism that is directed toward said test chamber, is provided with a sealing bead that is in contact with a region of said housing bore disposed between said receiving opening and said sealing lip.

3. An apparatus according to claim 2, in which said sealing bead is in the form of a resilient sealing ring that is disposed in an annular groove formed in said transfer slide mechanism.

4. An apparatus according to claim 1, in which said channel means is a bore that extends through said transfer slide mechanism.

5. An apparatus according to claim 1, in which said channel means is a groove that extends over at least 180°

of an outside surface of said transfer slide mechanism.

6. An apparatus according to claim 1, wherein said sealing lip engages said transfer slide mechanism in a sealing and wiping manner only when said transfer slide mechanism is moved out of said filling position thereof and into said test position.

7. An apparatus according to claim 2, wherein said sealing bead is disposed on a lower portion of said transfer slide mechanism that is directed toward said test chamber.

8. An apparatus according to claim 7, wherein said lower portion of said transfer slide mechanism extends beyond said sealing lip remote from said receiving opening, with said sealing lip already engaging said lower portion of said transfer slide mechanism in said filling position thereof.

9. An apparatus according to claim 7, wherein said housing and said portion of said transfer slide mechanism that is provided with said channel means are made of polypropylene, while said lower portion of said transfer slide mechanism with said sealing bead is made of an ABS copolymer.