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System for controlled release of antiarrhythmic agents

  • US 5,387,419 A
  • Filed: 03/26/1993
  • Issued: 02/07/1995
  • Est. Priority Date: 03/31/1988
  • Status: Expired due to Fees
First Claim
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1. A method of making a device for controlled release of an antiarrhythmic drug comprising:

  • (a) forming a mixture of about 4 parts lidocaine hydrochloride;

    10 parts polyurethane prepolymer, said polyurethane prepolymer comprising about 0.21 parts diisocyanate monomer and about 0.79 parts polyether monomer; and

    about 0.74 μ

    M FeCl3 /g polyether monomer;

    (b) forming the mixture into a desired shape; and

    (c) curing the formed mixture at a temperature in the range of 50°

    C. to 60°

    C. for a period of time ranging from about 24 hours to 3 days.

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