Apparatus for powder filling antibody testing devices

• US 5,388,392 A
• Filed: 10/05/1992
• Issued: 02/14/1995
• Est. Priority Date: 10/05/1992
• Status: Expired due to Fees

• Current Assignee: V-Tech, Inc.
• Original Assignee: V-Tech, Inc.
• Inventors: Linnecke, Carl
• Primary Examiner(s): Coan, James F.
• Application Number:
  US07/956,308
• Time in Patent Office: 862 Days
• Field of Search: 53/527, 53/900, 53/281, 53/471, 53/438, 53/129.1, 53/282, 53/284.5, 422/101
• US Class Current: 53/527
• CPC Class Codes: B01L 2400/0406 capillary forces
• CPC Class Codes: B01L 3/5023 with a sample being transported to, and subsequently stored in an absorbent for analysis
• CPC Class Codes: B01L 3/50825 Closing or opening means, corks, bungs closures for containers B65D; means for removing stoppers B67B7/02
• CPC Class Codes: G01N 2035/00168 Manufacturing or preparing test elements
• CPC Class Codes: G01N 2035/00188 the analyte being in the solid state
• CPC Class Codes: G01N 2035/0431 characterised by material of construction
• CPC Class Codes: G01N 35/00 Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
• CPC Class Codes: Y10S 53/90 Capsules

Abstract

An apparatus for assembling antibody testing devices for use in conducting biotests which utilize a powder fluid absorbing material to fill the housing of the antibody testing devices. The apparatus has several stations at which the various assembly steps take place. At the first station, lower housing portions of the antibody testing device are loaded onto a conveyor belt. At a second station, the lower housing portions are loaded with a fluid absorbing powder. At a third station, the powder loaded lower housing portions are engaged with a slotted indexing carousel wheel and are carried away from the conveyor belt. At a fourth station, the liquid absorbing powder in the lower housing portion is compressed therein. At a fifth station, a disk of filter material is placed atop the liquid absorbing powder loaded into the housing portion. At a sixth station, caps carrying membranes which have been spotted with receptors are engaged with the powder filled housing portion. At a seventh station, the assembled antibody testing devices are disengaged from the slotted indexing carousel wheel and are returned to the conveyor belt. At an eight station, the assembled antibody testing devices are vacuumed free of any powder which may have collected there. At a ninth station, the slotted indexing carousel wheel is forced into precise alignment such that its slots are aligned with the other stations located therearound.

Claims

1. An apparatus for assembling the compounds of an antibody testing device, utilizing powder as a fluid absorbing means, into a completed antibody testing device, comprising a station at which a lower housing portion is filled with a fluid absorbing powder, a station at which a disk of filter membrane is placed on top of said liquid absorbing powder in said lower housing portion, and a station at which a membrane carrying cap portion of the antibody testing device is engaged with said lower housing portion to complete the assembling of the antibody testing device.

2. The apparatus of claim 1, wherein a station is provided to compress said liquid absorbing powder into said lower housing portion.

3. The apparatus of claim 1, where said station at which said disk of filter material is place on top of said liquid absorbing powder in said lower housing portion is located in the vicinity of a slotted indexing carousel wheel.

4. The apparatus of claim 1, wherein a vacuuming station is provided after the antibody testing device is assembled to remove any liquid absorbing powder which may have deposited on an exterior surface of said assembled antibody testing device.

5. The apparatus of claim 2, wherein said station at which said cap portions are engaged with said lower housing portions and said station at which the liquid absorbing powder is compressed are located in the vicinity of a slotted indexing carousel wheel.

6. An apparatus for assembling the components of an antibody testing device, utilizing powder as a fluid absorbing means, into a completed antibody testing device, comprising:

(a) a first station at which a lower housing portion of the antibody testing device is placed on said apparatus;

(b) a second station at which said lower housing portion is filled with a liquid absorbing powder;

(c) a third station at which said housing portion is engaged with a slot on a slotted indexing carousel wheel;

(d) a fourth station at which said liquid absorbing powder in said lower housing portion of said antibody testing device is compressed into said lower housing portion;

(e) a fifth station at which a filter disk is placed atop said compressed liquid absorbing powder loaded in said lower housing portion;

(f) a sixth station at which a membrane carrying cap portion of the antibody testing device is engaged with said lower housing portion to complete the assembly of the antibody testing device; and

(g) a seventh station at which said assembled antibody testing device is disengaged from said slotted indexing carousel wheel.

7. The apparatus for assembling antibody testing devices of claim 6, wherein all stations are timed to function simultaneously, with different antibody testing devices in various states of assembly advancing in sequence through the various stations.

8. The apparatus for assembling antibody testing devices of claim 6, wherein a vacuuming station is provided to remove by vacuuming any powder which may have accumulated on the outside of said completed antibody testing device.

9. The apparatus for assembling antibody testing devices of claim 6, wherein an indexing station is provided to precisely align said slots in said slotted indexing carousel wheel with said other stations.

10. The apparatus for assembling antibody testing devices of claim 6, wherein said second station comprises a powder filling machine which delivers a predetermined quantity of a powder to said lower housing portion of said antibody testing device.

11. The apparatus for assembling antibody testing devices of claim 6, wherein said slotted indexing carousel wheel is rotated in precise steps by a stepper motor.

12. An apparatus for assembling the compounds of an antibody testing device, utilizing powder as a fluid absorbing means, into a completed antibody testing device, comprising a station at which a lower housing portion is filled with a fluid absorbing powder, a station at which a membrane carrying cap portion of the antibody testing device is engaged with said lower housing portion, and a vacuuming station at which any liquid absorbing powder which may have deposited on an exterior surface of said assembled antibody testing device is removed, to complete the assembling of the antibody testing device.

13. The apparatus of claim 12, wherein a station is provided to place a disk of filter membrane on top of said liquid absorbing powder in said lower housing portion.

14. The apparatus of claim 12, wherein a station is provided to compress said liquid absorbing powder into said lower housing portion.

15. The apparatus of claim 13, wherein said station at which said disk of filter material is placed on top of said liquid absorbing powder in said lower housing portion is located in the vicinity of a slotted indexing carousel wheel.

16. The apparatus of claim 14, wherein said station at which said cap portions are engaged with said lower housing portions and said station at which the liquid absorbing powder is compressed are located in the vicinity of a slotted indexing carousel wheel.