Measurement of bladder oxygen

• US 5,389,217 A
• Filed: 04/28/1994
• Issued: 02/14/1995
• Est. Priority Date: 04/28/1994
• Status: Expired due to Fees

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Biomedical Sensors Limited (Allegro Biodiesel Corp.)
• Inventors: Singer, Mervyn
• Primary Examiner(s): Niebling, John
• Assistant Examiner(s): Bell, Bruce F.
• Application Number:
  US08/234,083
• Time in Patent Office: 292 Days
• Field of Search: 204/415, 204/153.12, 204/153.16, 204/153.17, 204/153.1, 128/635, 128/637, 128/639, 128/656, 128/657, 128/658, 604/96
• US Class Current: 205/782.5
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/6853 with a balloon
• CPC Class Codes: A61B 5/6855 with a distal curved tip
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00

Abstract

An apparatus for the determination and continuous monitoring of bladder epithelial oxygen (pbO₂) which comprises, in combination, an introductory catheter with an inflatable placement cuff and an oxygen sensor, wherein the sensor is completely accommodated within the catheter when not in use and, when the apparatus is placed within a patient'"'"'s bladder, the sensor is adapted to be deployed so that the distal end of the sensor passes through an open port in the distal wall of the catheter and extends beyond the tip of the catheter to rest against the wall of the bladder; and a method for the continuous monitoring of pbO₂ using such apparatus.

Claims

1. An apparatus for the determination and continuous monitoring of bladder epithelial oxygen (pbO₂) which comprises, in combination, an introductory catheter and an oxygen sensor, wherein said catheter comprises an elongated hollow tube having channels therein, a proximal end and a distal end, which distal end forms a tip having an open port at or near the distal termination thereof and inflatable placement means located proximal to the open port, each of said channels terminating in a port at the proximal end of the catheter, a first port is connected to means for inflating the placement means, a second port is the terminal proximal end of a second channel terminating in the open port in the tip of the catheter and a third port is the terminal proximal end of a drainage channel, said oxygen sensor comprising an elongated sensor having a distal end and a proximal end, said distal end comprising an oxygen-sensing element enveloped within an oxygen-permeable membrane, the sensor is completely accommodated within the second channel of the catheter and, when the apparatus is placed within a patient'"'"'s bladder, wherein the distal end of the sensor passes through the open port and extends beyond the tip of the catheter, the proximal end of the sensor having a connector attached to a monitor.

2. An apparatus according to claim 1, in which the inflatable placement means is an inflatable balloon.

3. An apparatus according to claim 1, in which the second channel of the catheter which accommodates the oxygen sensor, and the drainage channel, each of which terminates in a separate port at the proximal end of the catheter, merge to form a single channel terminating in the open port at or near the distal end of the catheter.

4. An apparatus according to claim 1, in which the oxygen-sensing element of the oxygen sensor comprises two insulated conductors mounted in parallel within a chamber defined by a polyethylene membrane and having exposed distal portions comprising, respectively, an anode and a cathode, immersed in an electrolyte.

5. A method for the continuous monitoring of bladder epithelial oxygen (pbO₂) which comprises introducing into the bladder of a patient an apparatus comprising, in combination, an introductory catheter and an oxygen sensor, wherein said catheter comprises an elongated hollow tube having channels therein, a proximal end and a distal end, which distal end forms a tip having an open port at or near the distal termination thereof and inflatable placement means located proximal to the open port, each of said channels terminating in a port at the proximal end of the catheter, a first port be connected to means for inflating the placement means, a second port is the terminal proximal end of a second channel terminating in the open port in the tip of the catheter and a third port is the terminal proximal end of a drainage channel, said oxygen sensor comprising an elongated sensor having a distal end and a proximal end, said distal end comprising an oxygen-sensing element enveloped within an oxygen-permeable membrane, the sensor is completely accommodated within the second channel of the catheter, deploying the distal end of the oxygen sensor through the open port in the tip of the catheter so that the sensor extends beyond the tip and rests against the wall of the bladder, inflating the placement means so that the apparatus is held within the bladder, connecting the proximal end of the sensor to a monitor and obtaining desired readings from the monitor.