Pressure-sensitive poly(n-vinyl lactam) adhesive composition and skin covering articles using same
First Claim
1. A mammalian skin covering comprising:
- an adhesive layer for contacting mammalian skin and backing layer, the adhesive layer adhered to the backing layer and comprising a hydrophilic, pressure-sensitive adhesive composition of swellable, solid poly(N-vinyl lactam) radiation-crosslinked and an essentially unirradiated plasticizer present in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition.
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Abstract
A hydrophilic, pressure-sensitive adhesive composition prepared by irradiating solid poly(N-vinyl lactam) with ionizing radiation to crosslink the poly(N-vinyl lactam) and thereafter mixing the radiation-crosslinked poly(N-vinyl lactam) with essentially unirradiated plasticizer in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition. The composition is useful as a biomedical adhesive for transmitting or receiving electrical signals as a component of a biomedical electrode. The composition is also useful as a drug delivery device to deliver pharmaceuticals or other active ingredients to or through mammalian skin. The composition is also useful as a component in a skin covering for protecting mammalian skin or mammalian skin openings with antimicrobial agents. A method of preparation of the composition is also disclosed.
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Citations
28 Claims
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1. A mammalian skin covering comprising:
- an adhesive layer for contacting mammalian skin and backing layer, the adhesive layer adhered to the backing layer and comprising a hydrophilic, pressure-sensitive adhesive composition of swellable, solid poly(N-vinyl lactam) radiation-crosslinked and an essentially unirradiated plasticizer present in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition.
- View Dependent Claims (2, 3, 4, 5)
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6. A pharmaceutical delivery device comprising:
- an adhesive layer for contacting mammalian skin and a backing layer, the adhesive layer adhered to the backing layer and comprising a hydrophilic, pressure-sensitive adhesive composition of swellable, solid poly(N-vinyl lactam) radiation-crosslinked and an essentially unirradiated plasticizer present in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition.
- View Dependent Claims (7, 8)
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9. A hydrophilic, pressure-sensitive adhesive composition comprising:
- poly(N-vinyl lactam) radiation-crosslinked while in a solid form, an essentially unirradiated plasticizer present in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition, and an anti-microbial agent.
- View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18)
- 19. A hydrophilic, pressure-sensitive adhesive composition comprising poly(N-vinyl lactam) radiation-crosslinked while in solid form, an essentially unirradiated plasticizer present in an amount sufficient to form a cohesive, pressure-sensitive adhesive composition, and a therapeutic agent.
Specification