Method and system for effecting weight reduction of living beings

• US 5,391,143 A
• Filed: 03/12/1993
• Issued: 02/21/1995
• Est. Priority Date: 03/12/1993
• Status: Expired due to Fees

• Current Assignee: Kensey Nash Corporation (DSM-Firmenich AG)
• Original Assignee: Kensey Nash Corporation (DSM-Firmenich AG)
• Inventors: Kensey, Kenneth
• Primary Examiner(s): KRUTER, JEROME
• Application Number:
  US08/031,005
• Time in Patent Office: 711 Days
• Field of Search: 604/5, 604/28, 604/29, 604/30
• US Class Current: 604/5.03
• CPC Class Codes: A61M 1/3695 with sedimentation by gravity
• CPC Class Codes: A61M 2202/0071 product to be retained or harvested, e.g. by pheresis
• CPC Class Codes: A61M 2202/0405 Lymph
• CPC Class Codes: A61M 2202/046 Low-density lipoprotein
• CPC Class Codes: A61M 2202/08 Lipoids
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 27/002 Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202

Abstract

Method and systems for separating a first material, e.g., fat, from lymphatic fluid flowing through a duct within the body of a living being, so that the material is removed from the being'"'"'s body or recirculated. The system comprises a reservoir for receipt of that material, and an elongated conduit implanted within the vascular system and having a distal end in fluid communication with the duct and a proximal end in fluid communication with the reservoir. An implantable pump and/or valve may be provided to effect the operation of the system under control from outside the body of the being.

Claims

1. A method for effecting obesity control of a living being by removing at least one fat-like material from the lymphatic fluid flowing through the body of said living being, said fat-like material being selected from the group consisting of fats, cholesterols, phosphoglycerides, triglycerides, and lipoproteins, said method comprising coupling a first conduit to a duct within the body of said being having said lymphatic fluid flowing therethrough so that said lymphatic fluid flows into through said first conduit, whereupon said fat-like material within the lymphatic fluid is removed from the body of the being continually over a protracted period of time.

2. The method of claim 1 additionally comprising separating said at least one fat-like material from said lymphatic fluid and returning the remaining lymphatic fluid after separation of said at least one fat-like material therefrom to a first internal portion of the body of said being.

3. The method of claim 2 wherein said first internal portion of the body of said being comprises the peritoneum.

4. The method of claim 2 wherein said first internal portion of the body of said being comprises the gastro-intestinal tract.

5. The method of claim 2 wherein said first internal portion of the body of said being comprises the thoracic cavity.

6. The method of claim 2 wherein said first internal portion of the body of said being comprises the venous system.

7. The method of claim 2 wherein said remaining lymphatic fluid is provided to said first internal portion of the body of said being for reabsorption thereby on a continuous basis.

8. The method of claim 1 additionally comprising providing said separated fat to a second internal portion of the body of said being for excretion therefrom.

9. The method of claim 8 wherein said second internal portion of the body of said being comprises the urinary bladder.

10. The method of claim 1 wherein the fat is separated from said lymphatic fluid by gravity.

11. A method for removing at least one-fat like material from lymphatic fluid flowing through the body of a living being, said fat-like material being selected from the group consisting of fats, cholesterols, phosphoglycerides, triglycerides, and lipoproteins, said method comprising separating said at least one fat-like material from said lymphatic fluid flowing through the body of said living being and returning the remaining lymphatic fluid after separation of said at least one fat-like material therefrom to a first internal portion of the body of said being for reabsorption of said remaining lymphatic fluid by said body.

12. The method of claim 11 wherein said first internal portion of the body of said being comprises the peritoneum.

13. The method of claim 11 wherein said first internal portion of the body of said being comprises the gastro-intestinal tract.

14. The method of claim 11 wherein said first internal portion of the body of said being comprises the thoracic cavity.

15. The method of claim 11 wherein said first internal portion of the body of said being comprises the venous system.

16. The method of claim 11 wherein said remaining lymphatic fluid is provided to said first internal portion of the body of said being for reabsorption thereby on a continuous basis.

17. A method for removing at least one predetermined material from the lymphatic fluid flowing through the body a living being continually over a protracted period of time, said method comprising extending a first conduit through the venous system of the being, coupling said first conduit to a duct within the body of said being having said lymphatic fluid flowing therethrough so that said lymphatic fluid flows into through said first conduit, and thereafter removing said at least one predetermined material from said lymphatic fluid via said first conduit continually over a protracted period of time.

18. The method of claim 17 wherein said first conduit is implanted subcutaneously.

19. A system for removing a first fat-like material from lymphatic fluid flowing through the body of a living being on a continual basis over a protracted period of time, said first fat-like material being selected from the group consisting of fats, cholesterols, phosphoglycerides, triglycerides, and lipoproteins, said system comprising first conduit means and reservoir means, said first conduit means being configured to be located within the body of said being coupled to a duct within the body of said being having said lymphatic fluid flowing therethrough so that said lymphatic fluid flows into said conduit means, said conduit means being coupled to said reservoir means for carrying said lymphatic fluid into said reservoir means, said reservoir means being operative for causing said fat-like material in said lymphatic fluid to be separated therefrom, whereupon said fat-like material is removed from the body of said being.

20. The system of claim 19 wherein said system additionally comprises second conduit means coupled to said reservoir means and to a first internal portion of the body of said being for carrying the lymphatic fluid remaining after the separation of said first material therefrom to said first internal portion for reabsorption by said first internal portion.

21. The system of claim 20 wherein said system additionally comprises third conduit means coupled to said reservoir means and to a second internal portion of the body of said being for carrying said first material after it has been separated from said lymphatic fluid to said second internal portion for excretion thereby.

22. The system of claim 19 wherein said system additionally comprises third conduit means coupled to said reservoir means and to a second internal portion of the body of said being for carrying said first material after it has been separated from said lymphatic fluid to said second internal portion for excretion thereby.

23. The system of claim 19 additionally comprising actuatable means located within the body of said being for causing said system to operate when said actuatable means is actuated and for causing said system to cease operating when said actuatable means is deactuated.

24. The system of claim 23 wherein said actuatable means is actuated and deactuated from outside of the body of said being.

25. The system of claim 24 wherein said actuatable means comprises pumping means.

26. The system of claim 24 wherein said actuatable means comprises valve means.

27. The system of claim 26 wherein said actuatable means comprises pumping means.

28. The system of claim 23 wherein said actuatable means comprises pumping means.

29. The system of claim 23 wherein said actuatable means comprises valve means.

30. The system of claim 29 wherein said actuatable means comprises pumping means.

31. The system of claim 23 wherein said system is implantable within the body of said being for disposition therein over a protracted period of time.

32. The system of claim 19 wherein said reservoir means is configured so that said first material is separated from said lymphatic fluid within said reservoir means by gravity.

33. The system of claim 26 wherein said system is implantable within the body of said being for disposition therein over a protracted period of time.

34. The system of claim 33 wherein said first conduit comprises an elongated member having a distal portion and a proximal portion, said elongated conduit being extendable through a portion of the vascular system of said so that said distal portion is in fluid communication with said duct and said proximal portion is in fluid communication with said reservoir means.

35. The system of claim 34 wherein said actuatable means is actuated and deactuated from outside of the body of said being.

36. The system of claim 35 wherein said actuatable means comprises pumping means.

37. The system of claim 35 wherein said actuatable means comprises valve means.

38. The system of claim 37 wherein said actuatable means comprises pumping means.

39. The system of claim 26 wherein said first conduit comprises an elongated flexible member having a distal portion and a proximal portion, said elongated flexible conduit being extendable through a portion of the vascular system of said so that said distal portion is in fluid communication with said duct and said proximal portion is in fluid communication with said reservoir means.

40. An implantable system for removing a first fat-like material from lymphatic fluid flowing through the body of a living being on a continual basis over a protracted period of time, said first fat-like material being selected from the group consisting of fats, cholesterols, phosphoglycerides, triglycerides, and lipoproteins, said system comprising first conduit means and control means, said first conduit means being configured to be located within the body of said being coupled to a duct within the body of said being having said lymphatic fluid flowing therethrough so that said lymphatic fluid flows into said conduit means, said conduit means being coupled to said control means, said control means being operative for causing said lymphatic fluid to be provided to means for removing said fat-like material from said lymphatic fluid and for discharging said fat-like material from the body of said being.

41. The system of claim 40 wherein said control means comprises an outlet coupled to a first internal portion of the body of said being so that said lymphatic fluid provided to said first internal portion of the body of said being is excreted therefrom.

42. The system of claim 41 wherein said control means comprises valve and pumping means.

43. The system of claim 40 wherein said control means comprises valve and pumping means.

44. The system of claim 40 wherein said first conduit means is arranged for extension through the venous system.

45. The system of claim 40 wherein said first conduit means is arranged for subcutaneous disposition within the body of said being.

46. An implantable system for controlling obesity in a living being by removing at least one fat-like material from the lymphatic fluid flowing through the body of said being, said at least one fat-like material being selected from the group consisting of fats, cholesterols, phosphoglycerides, triglycerides, and lipoproteins, said system comprising first conduit means configured to be located within the body of said being coupled to a duct within the body of said being having said lymphatic fluid flowing therethrough and also coupled to a first internal portion of the body of said being so that a controlled portion of said lymphatic fluid flows into said first conduit means to have said at least one fat-like material separated therefrom for removal from the being'"'"'s lymphatic system, with at least a portion of said drained lymphatic fluid being provided to said first internal portion for reabsorption thereby.

47. The system of claim 46 wherein the amount of lymphatic fluid drained from said duct by said first conduit is controllable.

48. The system of claim 47 additionally comprising implantable control means coupled to said conduit for controlling the amount of lymphatic fluid drained from said duct by said first conduit means.

49. The system of claim 48 wherein said implantable control means comprises valve and pumping means.

50. A method for controlling obesity in a living being, said method comprising implanting first conduit means within the body of said being coupled so that said means is coupled to a duct within the body of said being having lymphatic fluid flowing therethrough and is also coupled to a first internal portion of the body of said being, draining a portion of said lymphatic fluid into said first conduit means from the being'"'"'s lymphatic system, and providing at least a portion of said drained lymphatic fluid to said first internal portion for reabsorption thereby.

51. The method of claim 50 wherein the amount of lymphatic fluid drained from said duct by said first conduit means is controlled.

52. The method of claim 51 additionally comprising implanting control means within the body of said being, said control means being coupled to said first conduit means for controlling the amount of lymphatic fluid drained from said duct by said first conduit means.

53. The method of claim 52 wherein said implantable control means comprises valve and pumping means, and wherein said method comprises selectively operating said valve and pumping means.

54. The method of claim 50 wherein said first internal portion of the body of said being comprises the upper portion of the gastro-intestinal tract.

55. The method of claim 50 wherein said first internal portion of the body of said being comprises the peritoneum.

56. A system for removing a first predetermined material from the body of a living being on a continual basis over a protracted period of time, said system comprising first conduit means, reservoir means, and implantable control means, said first conduit means being configured to be located within the body of said being coupled to a duct within the body of said being having lymphatic fluid flowing therethrough so that said lymphatic fluid flows into said first conduit means, said first conduit means being coupled to said reservoir means for carrying said lymphatic fluid into said reservoir means, said reservoir means being operable to cause said first material in said lymphatic fluid to be separated therefrom. whereupon said first material is removed from the body of said being, said implantable control means being coupled to said first conduit means for controlling the amount of lymphatic fluid drained from said duct by said first conduit means.

57. The system of claim 56 wherein said implantable control means comprises valve and pumping means.

58. A method for withdrawing a portion of lymphatic fluid flowing through a duct within the body of a living being, said method comprising implanting first conduit means within the body of said being coupled so that said first conduit means is coupled to a duct within the body of said being having lymphatic fluid flowing therethrough and is also coupled to a first internal portion of the body of said being so that a portion of said lymphatic fluid is drained from said duct into said first conduit means, implanting control means within the body of said being, said control means being coupled to said first conduit means for controlling the amount of lymphatic fluid drained from said duct by said first conduit means, and providing at least a portion of said drained lymphatic fluid to said first internal portion for reabsorption thereby.

59. The method of claim 58 wherein said implantable control means comprises valve and pumping means, and wherein said method comprises selectively operating said valve and pumping means.

60. The method of claim 58 wherein said first internal portion of the body of said being comprises the upper portion of the gastro-intestinal tract.

61. The method of claim 58 wherein said first internal portion of the body of said being comprises the peritoneum.

62. A method for removing at least one fat-like material from the body of living being, said fat-like material being selected from the group consisting of fats, cholesterols, phosphoglycerides, triglycerides, and lipoproteins, said method comprising coupling a first conduit to a duct within the body of said being having lymphatic fluid flowing therethrough so that said fluid flows into and through said first conduit, whereupon said fat-like material within said lymphatic fluid is removed from the body of said being continually over a protracted period of time.

63. The method of claim 62 wherein said at least one fat-like material is removed from the body of said being continuously.

64. The method of claim 63 additionally comprising separating said at least one fat-like material from said lymphatic fluid and returning the remaining lymphatic fluid after separation of said at least one fat-like material therefrom to a first internal portion of the body of said being.

65. The method of claim 62 additionally comprising separating said at least one fat-like material from said lymphatic fluid and returning the remaining lymphatic fluid after separation of said at least one fat-like material therefrom to a first internal portion of the body of said being.