Subcutaneous injector

• US 5,391,151 A
• Filed: 08/02/1993
• Issued: 02/21/1995
• Est. Priority Date: 01/15/1991
• Status: Expired due to Term

• Current Assignee: Meridian Medical Technologies Incorporated
• Original Assignee: Survival Technology, Inc. (Meridian Medical Technologies Incorporated)
• Inventors: Wilmot, John G.
• Primary Examiner(s): WEISS, JOHN
• Application Number:
  US08/087,804
• Time in Patent Office: 568 Days
• Field of Search: 604/136, 604/135, 604/138, 604/139, 604/187, 604/134
• US Class Current: 604/139
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/3131 specially adapted for improving sealing or sliding
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing

Abstract

A disposable, automatic, injector is disclosed which allows self-administration of a medicament to be injected subcutaneously. The injector comprises a barrel (1) with an inner chamber bounded by a liner (2). A first piston (4) and a second piston (11) are provided which may slide within the chamber with a fluid-tight seal with the liner (2). The second piston (11) carries an injection needle (13). A drive means, comprising a compression spring (5) and a releasable retaining collet (6), is provided to act on the first piston (4) to drive it towards the second piston (11). In operation, the drive means urges the first piston towards the second (11). The injection fluid, initially stored between the first and second pistons is incompressible and causes the second piston (11) to move until the needle (13) projects from the end of the barrel (1). When the needle (13) is fully extended the second piston (11) stops but the first piston (4) continues to move so causing injection fluid to be forced out through the needle (13).

Claims

1. An automatic injector comprising:

a body;

a charge of medicament normally disposed within said body;

a needle normally disposed in a normally sealed air-space within said body;

a seal for sealing said air-space at a forward end of said body, said needle being drivable into a projecting position from the forward end of said body through a predetermined portion of said seal;

a moveable plunger for forcing said medicament through said needle; and

a releasable spring for driving said needle from said air-space into said projecting position from the forward end of said body and for moving said plunger to force said medicament through said needle,

said injector having a normally sealed air release path associated therewith, said air release path being conditionable to permit at least some of the air normally contained in said air-space to exit said injector body before said needle is driven through said predetermined portion of said seal.

2. An automatic injector as claimed in claim 1, wherein said needle is driven into said projecting position from said body before said plunger is moved to force said medicament through said needle.

3. The injector according to claim 1, wherein said air release path permits air normally contained in said air-space to exit said injector body at a position which is spatially separated from said predetermined portion of said seal through which said needle is driven.

4. The injector according to claim 1, further comprising a barrel liner disposed in said body and a second plunger forwardly confining said medicament within said barrel liner in said body, said air release path being normally sealed by sealing contact between said seal and said barrel liner, said air release path being conditionable to permit said air normally contained within said air-space to exit said injector when said air normally contained within said air-space is compressed by movement of second movable plunger to force said seal and barrel liner to be moved out of said sealing contact therebetween.

5. An automatic injector comprising:

a body having a forward and rearward end;

a charge of medicament disposed within said body;

a needle having at least a portion thereof normally disposed in an air-space within said body, said needle having a longitudinal axis and being moveable along said axis to a fully projecting position in which a forward portion thereof projects from the forward end of said body, said needle being capable of dispensing said medicament when in said fully projecting position;

a moveable plunger capable of forcing said medicament through said needle to enable said needle to dispense said medicament; and

a releasable spring which, when released, operates to move said needle along said axis to said fully projecting position and to move said plunger so that said plunger forces said medicament through said needle when said needle is in said fully projecting position;

said injector being provided with an air release path through which air can escape from said air-space during an injection operation in which said releasable spring is released so that said needle moves along said axis to said fully projecting position, said air release path extending in a direction transverse to said longitudinal axis.

6. An automatic injection as claimed in claim 5, further comprising a forward piston forwardly confining said medicament, wherein a rearward end of said needle pierces said forward piston to expose a rearward opening of said needle to the medicament after said needle is moved to said fully projecting position.

7. An automatic injector as claimed in claim 5, wherein a seal member operates to forwardly confine said air contained within said air-space before said needle is moved to said fully projecting position, said seal member having an outer surface which defines at least part of said air release path.

8. An automatic injector as claimed in claim 7, wherein said seal member is covered by an end cap, said seal member and said end cap being punctured by said needle when said needle is moved along said longitudinal axis toward said fully projecting position.

9. An automatic injector as claimed in claim 8, wherein said air release path is provided, at least in part, between said seal member and said end cap.

10. An automatic injector comprising:

a body having a forward and rearward end;

forward and rearward pistons, said pistons being slidably moveable within said body;

a charge of medicament disposed between said forward and rearward pistons;

a needle having at least a portion thereof disposed in a sealed air-space within said body, said needle having a longitudinal axis and being moveable along said axis into a fully projecting position in which a forward portion of the needle projects from the forward end of said body, said needle having a rearward opening for receiving said medicament and a forward opening for dispensing said medicament; and

a releasable drive means for (1) driving said forward piston, said rearward piston and said medicament contained therebetween toward the forward end of the body, and (2) moving the needle along said longitudinal axis to said fully projecting position, said needle reaching said fully projecting position before said medicament is permitted to be dispensed from said forward opening of said needle;

said injector being provided with an air release path through which air contained within said air-space can be exhausted from said body as said needle is moved into said fully projecting position, said air release path extending in a transverse direction from said longitudinal axis of said needle.

11. An automatic injector as claimed in claim 10, wherein said needle is moved to said fully projecting position before said medicament is permitted to enter said rearward opening of said needle.

12. An automatic injector as claimed in claim 11, wherein a rearward end of said needle pierces said forward piston to expose said rearward opening of said needle to the medicament after said needle is moved to said fully projecting position.

13. An automatic injector as claimed in claim 10, wherein a seal member operates to forwardly confine said air contained within said air-space before said needle is moved into said fully projecting position, said seal member having an outer surface which defines at least part of said air release path.

14. An automatic injector as claimed in claim 13, wherein said seal member is covered by an end cap, said seal member and said end cap being punctured by said needle when said needle is moved along said longitudinal axis toward said fully projecting position.

15. An automatic injector as claimed in claim 14, wherein said air release path is provided, at least in part, between said seal member and said end cap.

16. An automatic injector as claimed in claim 10, wherein said releasable drive means comprises a spring.

17. An automatic injector as claimed in claim 10 wherein the needle passes through a guide seal which provides a sealingly sliding fit with said needle as said needle is driven into said projecting position.

18. An automatic injector as claimed in claim 17, wherein a forward tip of said needle is normally buried in said guide seal before it is driven into said projecting position.

19. An automatic injector comprising:

a body;

a barrel liner disposed within said body;

a charge of medicament normally disposed within said barrel liner;

a first plunger rearwardly confining said medicament within said barrel liner, said first plunger being movable within said barrel liner to dispense said medicament;

a second plunger forwardly confining said medicament within said barrel liner;

a seal disposed in normally sealing relation with said barrel liner at a forward portion thereof, said seal and said second plunger defining a normally sealed air space therebetween in said barrel liner;

a needle normally disposed in said sealed air-space within said barrel liner generally between said seal and said second plunger, said needle being drivable from said sealed air-space through a predetermined portion of said seal into a projecting position from the forward end of said body;

said seal being conditionable to permit at least a portion of the air normally sealed within said air space to escape therefrom at a position spaced from said predetermined portion of said seal through which said needle is driven; and

a releasable spring being releasable to i) drive said second movable plunger forwardly within said liner and thereby compress air normally disposed within said air space ii) drive said needle from said normally sealed air-space through said predetermined portion of the seal into said projecting position from the forward end of the body, iii) condition said seal to permit at least a portion of the air compressed in said air space to escape therefrom, and iv) move said first plunger within said barrel liner to dispense said medicament through said needle.

20. The injector according to claim 19, wherein said seal is conditioned to provide an air release path between said seal and said barrel liner, and wherein said air release path is normally sealed by sealing contact between said seal and said barrel liner, said air release path being conditionable to permit said air normally contained within said air-space to exit therefrom when said air normally contained within said air-space is compressed by movement of second movable plunger to force said seal and liner to be moved out of said sealing contact therebetween.

21. The injector according to claim 20, wherein said needle perforates said predetermined portion of seal to thereby provide an additional air release path between an exterior periphery of said needle and said seal to permit said air compressed within said air-space and normally disposed within said air-space to exit therefrom through said additional air release path.

22. The injector according to claim 19, wherein a rearward end of said needle perforates the second plunger so as to be in communication with the medicament after the needle is driven into said projecting position from the forward end of the body to thereby enable the needle to dispense the medicament therethrough.