Container with pierceable and/or collapsible features

• US 5,395,365 A
• Filed: 03/22/1993
• Issued: 03/07/1995
• Est. Priority Date: 03/22/1993
• Status: Expired due to Term

• Current Assignee: Catalent Pharma Solutions Incorporated (Catalent, Inc.), Catalent Pharma Solutions Limited (Catalent, Inc.), Catalent USA Packaging LLC (Catalent, Inc.), Catalent USA Paintball, Inc. (Catalent, Inc.), Catalent USA Woodstock, Inc. (Catalent, Inc.)
• Original Assignee: Cardinal Health 400, Inc.
• Inventors: Komendowski, Henry, Weiler, Gerhard H.
• Primary Examiner(s): Green, Randall L.
• Assistant Examiner(s): ZUTTARELLI, ANTHONY
• Application Number:
  US08/034,727
• Time in Patent Office: 715 Days
• Field of Search: 128/912, 128/D26, 128/D24, 604/56, 604/82-92, 604/148, 604/161, 604/200-205, 604/213, 604/240-247, 604/249, 604/256, 604/259, 604/323, 604/403, 604/411, 604/414, 604/415, 604/905 , 604/408-409, 215/230, 215/247, 215/321, 220/213, 220/253, 220/256-258, 206/505, 206/514, 206/515, 206/517
• US Class Current: 604/415
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 1/1475 Inlet or outlet ports
• CPC Class Codes: Y10S 128/24 Medical-surgical bags
• CPC Class Codes: Y10S 604/905 Aseptic connectors or couplings, e.g. frangible, piercable

Abstract

A hermetically sealed package is provided for the administration of a solution or other liquid to a patient. The package includes a blow molded container, cap, and releasable cover. The cap accommodates piercing of the cap and container with a draining spike. The cap has one or more self-closing seals or liners and can be disposed on the container so as to permit penetration of the cap and container by a piercing spike without contacting the parting line of the molded container. The cap includes a special structure for guiding the spike at the initiation of the piercing process, and the cap has an improved structure for sealingly engaging the spike upon insertion. As the container is drained, one of the container walls collapses toward the other to facilitate the draining process and provide a convenient shape for subsequent handling and storage.

Claims

1. A pierceable, unitary, molded container having a peripheral parting line that delineates opposing portions of the container and comprising:

a hollow body portion defining an access port and suitable for containing a substance to be drained therefrom;

a unitary sealing wall coextensive with and sealing said access port;

a pierceable membrane in said sealing wall; and

said sealing wall defining guide surfaces that converge toward said pierceable membrane and define to one side of said parting line a recess for receiving a piercing spike means therewith.

2. The container in accordance with claim 1 in which

said sealing wall defines two of said guide surfaces;

said guide surfaces each have a generally planar configuration; and

said guide surfaces meet to define a generally V-shaped concave recess having a vertex along which said pierceable membrane is defined.

3. The container in accordance with claim 2 in which

said hollow body portion has a boss defining a sump communicating with the interior of said body portion;

said boss defines said access port; and

said sealing wall defines an end of said boss.

4. The container in accordance with claim 2 in which said container is filled and hermetically sealed.

5. A sealed but pierceable package comprising:

a molded container having a peripheral parting line that delineates opposing portions of the container and an access port thereto defined by a boss unitary with said container and sealed by a unitary pierceable membrane;

a cap secured to said boss over said membrane, said cap including a pierceable, resilient, self-sealing liner juxtaposed over said container membrane; and

said self-sealing liner including an exposed target surface and a deformable interior surface facing toward said pierceable membrane to one side of said parting line, said deformable interior surface defining a recess aligned with said exposed target surface and providing an inwardly enlarging passageway for a piercing spike while supplying increased resistance against removal of said piercing spike when inserted through said target surface.

6. The package in accordance with claim 5 in which

said cap has an end wall and a depending peripheral skirt;

said liner is a thermoplastic polymer rubber that is molded into said cap; and

said cap end wall defines an aperture providing access to said exposed target surface of said liner.

7. The package in accordance with claim 6 in which

said enlarging passageway is defined by (1) a first cylindrical recess in said liner aligned with said exposed target surface and (2) a larger diameter second cylindrical recess in said liner that is coaxial with said first recess for providing an annular shoulder around said first recess which supplies increased resistance to removal of a piercing spike that has a diameter less than the diameter of said first recess and that is inserted through said liner in general alignment with said exposed target surface, first recess, and second recess to pierce said membrane.

8. The package in accordance with claim 5 in which said container is filled and hermetically sealed.

9. A pierceable package comprising:

a molded container having an access port thereto defined by a boss unitary therewith and sealed by a unitary pierceable membrane and having a peripheral parting line that delineates opposing portions of the container;

a cap mounted on said boss over said membrane and including a pierceable, resilient, self-closing seal in registry over an area of said container membrane to one side of said parting line, said cap including a housing that is substantially more rigid than said seal and that encloses said seal while exposing at least one pierceable target region of the seal, said housing being secured to said container boss to retain said seal in position and including an annular, raised rim around said seal target region; and

a removable cover releasably sealed to said housing rim over said self-closing seal to isolate said seal target region from the ambient atmosphere.

10. The package in accordance with claim 9 in which said container is filled and hermetically sealed.

11. A pierceable package comprising:

a molded container with a parting line delineating opposing portions of the molded container, said container having an access port thereto defined by a boss and sealed by a pierceable membrane; and

a cap for attachment to said boss over said membrane, said cap including a resilient, self-sealing liner having an exposed, pierceable, target portion over said container membrane;

said container boss and said cap having cooperating orientation means for the placement of said cap on said container boss in a predetermined orientation relative to one another and for positioning said target portion away from said parting line.

12. The package in accordance with claim 11 in which

said container is molded from thermoplastic material as a unitary structure which is filled and hermetically sealed;

and

said container parting line is defined at least in part by a ridge of said material extending across said membrane.

13. The package in accordance with claim 11 in which

said parting line extends across part of said membrane;

one of said cap and container defines a lug; and

the other of said cap and container defines a recess for engaging said lug when said cap and container are in said predetermined orientation whereby said target portion is displaced from said parting line and is absent from the region between said target portion and said membrane.

14. A molded, filled, and collapsible container from which a substance can be drained under the influence of gravity, said container comprising:

a molded body portion having a sump at one end of said body portion that communicates with the interior of said body portion, said sump including closure means for accommodating draining of said substance therethrough; and

said body portion being defined by a pair of opposed walls joined around at least a portion of the periphery of said body, one of said walls being structurally less stiff than the other wall and collapsing inwardly toward the other wall in a generally nesting relationship when said substance is drained from said container.

15. The container in accordance with claim 14 in which

both of said walls are flexible;

and

said one wall is thinner than the other wall.

16. The container in accordance with claim 14 in which said walls define oppositely projecting convex front and rear regions and define oppositely facing concave side edge regions where said walls are joined together.

17. The container in accordance with claim 16 in which the locus of the intersection of each said wall with a first selected plane defining a transverse cross section of said container has a length equal to the length of the locus of the intersection of the wall with a second selected plane parallel to, and spaced from, said first selected plane wherein said planes are longitudinally located to intersect said concave side edge regions.

18. The container in accordance with claim 14 in which

said body sump has an access port thereto defined by a boss;

and

said closure means includes a pierceable membrane sealing said access port.