Spinal puncture fluid collection apparatus

• US 5,396,899 A
• Filed: 04/28/1993
• Issued: 03/14/1995
• Est. Priority Date: 04/28/1993
• Status: Expired due to Fees

• Current Assignee: Duke University
• Original Assignee: Duke University
• Inventors: Strittmatter, Warren J.
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US08/054,802
• Time in Patent Office: 685 Days
• Field of Search: 128/763, 128/765, 128/766, 128/770, 604/403-406, 206/363-365, 206/370
• US Class Current: 600/576
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 17/3401 Puncturing needles for the peridural or subarachnoid space or the plexus, e.g. for anaesthesia local anaesthesia A61M19/00
• CPC Class Codes: A61B 2010/0077 Cerebrospinal fluid

Abstract

An apparatus for performing a spinal puncture on a subject to obtain a sample of cerebrospinal fluid is disclosed. The apparatus operates at ambient pressure. The spinal puncture apparatus is designed to interface with a sample container. A sample container apparatus is also disclosed, as is a kit for use in performing spinal puncture on a subject to obtain a sample of cerebrospinal fluid.

Claims

1. A spinal puncture apparatus for collecting cerebrospinal fluid from a patient into a sample container, comprising:

an elongate hollow spinal puncture needle having a lumen formed therein;

a junction member connected to said elongate hollow needle, said junction member having an outlet port and a stylet port formed therein, with said outlet port in fluid communication with said lumen and with said stylet port longitudinally aligned with said lumen;

penetrable seal means connected to said stylet port for preventing fluid flow therethrough;

a stylet slidably received in said lumen, said stylet penetrating through said penetrable seal means;

a coupling member connected to said outlet port and in fluid communication therewith, said coupling member configured to connect to said sample container; and

valve means connected to said junction member for blocking the flow of cerebrospinal fluid from said outlet port to said coupling member.

2. An apparatus according to claim 1, wherein said junction member comprises a hollow tube having first and second oppositely facing end portions and a side wall, wherein said spinal puncture needle is connected to said first end portion, wherein said stylet port is formed on said second end portion, and wherein said outlet port is formed on said side wall.

3. An apparatus according to claim 1, further comprising an elongate flexible tube interconnecting said outlet port and said coupling member so that said spinal puncture needle and said coupling member may be separately manipulated while said spinal puncture needle is inserted in a patient and said coupling member is connected to a sample container.

4. An apparatus according to claim 3, wherein said elongate flexible tube is substantially transparent.

5. An apparatus according to claim 1, further comprising a gas-permeable, water-impermeable filter connected to said junction member and in fluid communication with said lumen.

6. An apparatus according to claim 1, further comprising a gas-permeable, water-impermeable filter connected to said valve means, and wherein said valve means is switchable between a first position wherein said outlet port is in fluid communication with said filter and a second position wherein said outlet port is in fluid communication with said coupling member.

7. An apparatus according to claim 6, wherein said filter comprises a hydrophobic membrane.

8. An apparatus according to claim 1, wherein:

said needle has a proximal end and a distal end, with said proximal end connected to said junction member and said distal end having an end portion formed thereon;

said stylet has a proximal end and a distal end, with said proximal end having a graspable hub formed thereon, with said distal end having an end portion formed thereon;

said stylet port having a hub seat formed therein configured to receive said graspable hub in an aligned position;

said stylet configured in length so that when said graspable hub is received in said hub seat in said aligned position, said stylet end portion and said needle end portion together form a pointed tip portion having a substantially continuous surface thereon to facilitate penetration and withdrawal of said needle between the spinal vertebrae of a patient.

9. An apparatus according to claim 8, wherein said pointed tip portion comprises an angled tip portion.

10. A spinal puncture apparatus for collecting cerebrospinal fluid from a patient into a sample container, comprising:

an elongate hollow spinal puncture needle having a lumen formed therein;

a junction member connected to said elongate hollow needle, said junction member having an outlet port and a stylet port formed therein, with said outlet port in fluid communication with said lumen and with said stylet port longitudinally aligned with said lumen;

penetrable seal means connected to said stylet port for preventing fluid flow therethrough;

a stylet slidably received in said lumen, said stylet penetrating through said penetrable seal means;

a coupling member connected to said outlet port and in fluid communication therewith, said coupling member configured to connect to said sample container;

an elongate flexible tube interconnecting said outlet port and said coupling member so that said spinal puncture needle and said coupling member may be separately manipulated while said spinal puncture needle is inserted in a patient and said coupling member is connected to a sample container;

valve means connected to said junction member for blocking the flow of cerebrospinal fluid from said outlet port to said coupling member; and

a gas-permeable, water-impermeable filter connected to said valve means, and wherein said valve means is switchable between a first position wherein said outlet port is in fluid communication with said filter and a second position wherein said outlet port is in fluid communication with said coupling member.

11. An apparatus according to claim 10, wherein:

said needle has a proximal end and a distal end, with said proximal end connected to said junction member and said distal end having an end portion formed thereon;

said stylet has a proximal end and a distal end, with said proximal end having a graspable hub formed thereon, with said distal end having an end portion formed thereon;

said stylet port having a hub seat formed therein configured to receive said graspable hub in an aligned position;

said stylet configured in length so that when said graspable hub is received in said hub seat in said aligned position, said stylet end portion and said needle end portion together form a pointed tip portion having a substantially continuous surface thereon to facilitate penetration and withdrawal of said needle between the spinal vertebrae of a patient.

12. An apparatus according to claim 11, wherein said junction member comprises a hollow tube having first and second oppositely facing end portions and a side wall, wherein said spinal puncture needle is connected to said first end portion, wherein said stylet port is formed on said second end portion, and wherein said outlet port is formed on said side wall.

13. An apparatus according to claim 12, wherein said elongate flexible tube is substantially transparent.

14. An apparatus according to claim 12, wherein said filter comprises a hydrophobic membrane.

15. An apparatus according to claim 12, wherein said pointed tip portion comprises an angled tip portion.

16. A spinal puncture kit for collecting cerebrospinal fluid from a patient into a sample container, comprising:

(a) a sample container; and

(b) a spinal puncture apparatus, said spinal puncture apparatus comprising;

an elongate hollow spinal puncture needle having a lumen formed therein;

a junction member connected to said elongate hollow needle, said junction member having an outlet port and a stylet port formed therein, with said outlet port in fluid communication with said lumen and with said stylet port longitudinally aligned with said lumen;

penetrable seal means connected to said stylet port for preventing fluid flow therethrough;

a stylet slidably received in said lumen, said stylet penetrating through said penetrable seal means;

a coupling member connected to said outlet port and in fluid communication therewith, said coupling member configured to connect to said sample container; and

valve means connected to said junction member for blocking the flow of cerebrospinal fluid from said outlet port to said coupling member.

17. A kit according to claim 16, wherein said kit is contained in a single package.

18. A kit according to claim 17, wherein said kit is sterile.

19. A kit according to claim 16, further comprising an elongate flexible tube interconnecting said outlet port and said coupling member so that said spinal puncture needle and said coupling member may be separately manipulated while said spinal puncture needle is inserted in a patient and said coupling member is connected to a sample container.

20. A kit according to claim 16, further comprising a gas-permeable, water-impermeable filter connected to said junction member and in fluid communication with said lumen.

21. A kit according to claim 16, further comprising a gas-permeable, water-impermeable filter connected to said valve means, and wherein said valve means is switchable between a first position wherein said outlet port is in fluid communication with said filter and a second position wherein said outlet port is in fluid communication with said coupling member.

22. A kit according to claim 16, wherein:

said needle has a proximal end and a distal end, with said proximal end connected to said junction member and said distal end having an end portion formed thereon;

said stylet has a proximal end and a distal end, with said proximal end having a graspable hub formed thereon, with said distal end having an end portion formed thereon;

said stylet port having a hub seat formed therein configured to receive said graspable hub in an aligned position;

said stylet configured in length so that when said graspable hub is received in said hub seat in said aligned position, said stylet end portion and said needle end portion together form a pointed tip portion having a substantially continuous surface thereon to facilitate penetration and withdrawal of said needle between the spinal vertebrae of a patient.

23. A spinal puncture apparatus for collecting cerebrospinal fluid from a patient into a sample container, comprising:

an elongate hollow spinal puncture needle having a lumen formed therein;

a junction member connected to said elongate hollow needle, said junction member having an outlet port and a styler port formed therein, with said outlet port in fluid communication with said lumen and with said stylet port longitudinally aligned with said lumen;

penetrable seal means connected to said stylet port for preventing fluid flow therethrough;

a styler slidably received in said lumen, said stylet penetrating through said penetrable seal means;

a coupling member connected to said outlet port and in fluid communication therewith, said coupling member configured to connect to said sample container; and

valve means connected to said junction member for blocking the flow of cerebrospinal fluid from said outlet port to said coupling member; and

a gas-permeable, water-impermeable filter connected to said valve means, wherein said valve means is switchable between a first position wherein said outlet port is in fluid communication with said filter and a second position wherein said outlet port is in fluid communication with said coupling member.

24. An apparatus according to claim 23, wherein said filter comprises a hydrophobic membrane.

25. A spinal puncture kit for collecting cerebrospinal fluid from a patient into a sample container, comprising:

(a) a sample container; and

(b) a spinal puncture apparatus, said spinal puncture apparatus comprising;

an elongate hollow spinal puncture needle having a lumen formed therein;

a junction member connected to said elongate hollow needle, said junction member having an outlet port and a stylet port formed therein, with said outlet port in fluid communication with said lumen and with said stylet port longitudinally aligned with said lumen;

penetrable seal means connected to said stylet port for preventing fluid flow therethrough;

a stylet slidably received in said lumen, said stylet penetrating through said penetrable seal means;

a coupling member connected to said outlet port and in fluid communication therewith, said coupling member configured to connect to said sample container;

valve means connected to said junction member for blocking the flow of cerebrospinal fluid from said outlet port to said coupling member; and

a gas-permeable, water-impermeable filter connected to said valve means, wherein said valve means is switchable between a first position wherein said outlet port is in fluid communication with said filter and a second position wherein said outlet port is in fluid communication with said coupling member.

26. A spinal puncture kit according to claim 25, wherein said filter of said spinal puncture apparatus comprises a hydrophobic membrane.