Method and apparatus for artificially stimulating cough reflex

• US 5,397,337 A
• Filed: 03/29/1994
• Issued: 03/14/1995
• Est. Priority Date: 04/02/1992
• Status: Expired due to Fees

• Current Assignee: Illinois Institute of Technology, Rehabilitation Institute Research Corporation
• Original Assignee: Illinois Institute of Technology
• Inventors: Roth, Elliot J., Jaeger, Robert J.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Getzow, Scott M.
• Application Number:
  US08/219,250
• Time in Patent Office: 350 Days
• Field of Search: 607/62, 607/65
• US Class Current: 607/62
• CPC Class Codes: A61N 1/3601 of respiratory organs

Abstract

A method and apparatus for eliciting a physiologically significant cough reflex, such as in a quadriplegic patient. The apparatus preferably has at least one pair of electrodes which are positioned about or near the abdominal muscles. The user generates an input signal. The input signal and a stimulus pulse signal are computed into an output signal. Prior to the delivery of the output signal, alerting signals are delivered to the user to alert the user of an upcoming cough and the onset of pulse electrical voltage to allow the user to engage appropriate volitional activity to optimally engage and complete the cough. The output signal is transformed into a pulse electrical voltage which is delivered across each pair of electrodes. Such pulse electrical voltage activates the lower motor neurons and thereby contracts the abdominal muscles to elicit a physiologically significant cough reflex. The pulse electrical voltage can be delivered at an optimum time, which can be calculated as a function of a physical and temporal status of the cough and a volitional activity by the user, in order to achieve a maximum air flow rate of the cough.

Claims

1. An artificial cough reflex apparatus comprising:

at least one pair of electrodes, stimulator means for electronically receiving an input signal and computing an output signal corresponding to a stimulus time period, input means for generating said input signal as a representation of a volitional decision of a user to initiate a cough, signal means for alerting said user of an upcoming said cough, said stimulator means emitting said output signal after an adjustable time delay during which said user coordinates a volitional activity, transformer means for transforming said output signal into a pulse electrical voltage across each said pair of electrodes that activates lower motor neurons and contracts a plurality of expiratory muscles, said signal means for signalling said user to engage said volitional activity and complete said cough, and sensor means for calculating an optimal time as a function of a physical and temporal status of said cough and said volitional activity and for producing said pulse electrical voltage at said optimal time to maximize an air flow rate of said cough.

2. An artificial cough reflex apparatus according to claim 1 wherein said signal means emit an audible tone for indicating an onset of muscle stimulation to alert said user to initiate said volitional activity.

3. An artificial cough reflex apparatus according to claim 1 wherein said signal means comprise a light for indicating an onset of muscle stimulation.

4. An artificial cough reflex apparatus according to claim 1 wherein said signal means comprise vibration means for indicating an onset of muscle stimulation to alert said user to initiate said volitional activity.

5. An artificial cough reflex apparatus according to claim 1 wherein said signal means comprise stimulation means for applying a low level electrical stimulation to an innervated skin area of said user to alert said user to initiate said volitional activity.

6. An artificial cough reflex apparatus according to claim 1 wherein said signal means comprise production means for sounding a stored speech message to alert said user to initiate said volitional activity.

7. An artificial cough reflex apparatus according to claim 1 wherein said stimulator means further comprise logic computer means for receiving said input signal and computing and responsively emitting a computed logic signal.

8. An artificial cough reflex apparatus according to claim 7 wherein said stimulator means further comprise amplification means for amplifying and emitting said computed logic signal to said transformer means.

9. An artificial cough reflex apparatus according to claim 1 wherein said input means comprise an electromechanical pushbutton switch.

10. An artificial cough reflex apparatus according to claim 1 wherein said input means comprise transmitter means for selectively transmitting a frequency signal to said stimulator means.

11. An artificial cough reflex apparatus according to claim 1 wherein said input means comprise activation means for activating said input signal upon detection of a voice command.

12. A method for artificially inducing a cough, including the steps of:

(a) positioning at least one pair of electrodes about a plurality of abdominal muscles;

(b) generating an input signal representing a volitional decision of a user to initiate the cough;

(c) generating a signal to alert said user of an upcoming said cough;

(d) emitting a computed output signal after an adjustable time delay during which said user coordinates a volitional activity;

(e) transforming said output signal into a pulse electrical voltage across each said pair of electrodes;

(f) activating lower motor neurons and thereby contracting said abdominal muscles;

(g) signalling said user to engage said volitional activity and complete said cough;

(h) calculating an optimal time as a function of a physical and temporal status of the cough and said volitional activity; and

(i) producing said pulse electrical voltage at said optimal time to maximize air flow of the cough.

13. A method according to claim 12 wherein each said electrode is positioned on an outer skin layer near said abdominal muscles.

14. A method according to claim 12 wherein each said electrode is surgically implanted within a body near said abdominal muscles.

15. A method according to claim 12 wherein each said electrode is percutaneously inserted within a body near said abdominal muscles.

16. A method according to claim 12 wherein said output signal is an amplified computed logic signal derived from computing an input signal and said stimulus pulse signal.

17. A method according to claim 12 further including the step of transmitting a selected frequency to a receiver that converts said selected frequency into said input signal.