Combination monophasic action potential/ablation catheter and high-performance filter system

• US 5,398,683 A
• Filed: 07/16/1993
• Issued: 03/21/1995
• Est. Priority Date: 05/24/1991
• Status: Expired due to Term

• Current Assignee: EP Technologies Incorporated (Boston Scientific Corporation)
• Original Assignee: EP Technologies Incorporated (Boston Scientific Corporation)
• Inventors: Edwards, Stuart D., Franz, Michael R., Thompson, Russel B., Stern, Roger A.
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): Casler, Brian L.
• Application Number:
  US08/092,762
• Time in Patent Office: 613 Days
• Field of Search: 128/642, 607/116, 607/122, 607/154, 607/155, 606/41, 606/34
• US Class Current: 600/374
• CPC Class Codes: A61B 18/12 by passing a current through the tissue to be heated, e.g. high-frequency current
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/003 Steerable
• CPC Class Codes: A61B 2017/00473 Distal part, e.g. tip or head A61B2017/00464 takes precedence
• CPC Class Codes: A61B 2018/00107 Coatings on the energy applicator
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/0066 without feedback, i.e. open loop control
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/1253 monopolar
• CPC Class Codes: A61B 2018/126 bipolar
• CPC Class Codes: A61B 2018/1293 having means to prevent interference
• CPC Class Codes: A61B 2018/1495 Electrodes being detachable from a support structure
• CPC Class Codes: A61B 2018/1497 Electrodes covering only part of the probe circumference
• CPC Class Codes: A61B 2018/162 located on the probe body
• CPC Class Codes: A61B 2562/0215 Silver or silver chloride containing
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems

Abstract

A combination catheter for both detecting monophasic action potentials and ablating surface tissue in an in vivo heart of a patient is provided. The apparatus includes a catheter probe having a terminal tip portion and an electrode carried on the tip such that a portion of the tip electrode is exposed to ambient. A reference electrode is spaced along the tip from the first electrode for supplying a reference potential signal. An ablating electrode is located adjacent to but electrically insulated from both the tip and reference electrodes for providing electromagnetic energy to the tip. The electrodes are electrically connected to the proximal end of the catheter through individual conductors or wires that run through an insulated cable. An electronic filter is provided to permit the recording of MAPs during ablation without radiofrequency interference. The catheter may also include standard mapping and/or pacing electrodes. The catheter may further include a steering mechanism for positioning the catheter at various treatment sites in the heart, and a structure for holding the tip electrode in substantially perpendicular contact with heart tissue with a positive pressure, and for spacing the reference electrode from the heart tissue.

Claims

1. Apparatus for both detecting monophasic action potentials and ablating surface tissue in an in vivo heart of a patient, comprising:

a catheter having a proximal end and a distal end, said distal end having a terminal tip and an exterior surface, and said catheter being adapted for insertion into a patient for detecting said monophasic action potentials;

a first electrode carried at said distal terminal tip for contacting surface tissue of the heart of the patient for measuring potentials at said surface tissue;

a second electrode carried on said catheter and spaced from said first electrode for supplying a reference potential signal;

a third electrode carried on said catheter adjacent to said first electrode and electrically insulated from said first electrode for providing electromagnetic energy to said surface tissue;

first electrical means coupled to said first and second electrodes for generating signals representing action potentials, and

second electrical means coupled to said third electrode for providing said electromagnetic energy to said third electrode

wherein said third electrode comprises a ring made of a partially conductive material of variable thickness said ring having a proximal end and a distal end, and said thickness of said ring monotonically increasing from the distal end to the proximal end of said ring.

2. The apparatus of claim 1, wherein said partially conductive material is an epoxy.

3. A method for detecting monophasic action potentials and ablating surface tissue in an in vivo heart of a patient using a catheter having a proximal end and a distal end, with a first electrode, carried at the distal end, a second electrode carried on a surface of the catheter and spaced from the first electrode, and a third electrode adjacent to but electrically insulated by a skirt member having a thickness of 0.001 to 0.200 inches from the first electrode, including the steps of:

inserting the distal end into the heart;

positioning the distal end in a substantially perpendicular configuration against endocardium of the heart such that the first electrode contacts said endocardium with a force sufficient to depolarize myocardial cells in the vicinity of the first electrode and such that the second electrode does not contact said endocardium;

detecting first signals by means of said first and second electrodes, said first signals relating to the monophasic action potentials of the heart;

at about the same time as said detecting step is performed, delivering radiofrequency energy to the heart by means of said third electrode, said energy sufficient to ablate the heart tissue; and

repeating said detecting and delivering steps until no monophasic action potential signals are detected.

4. A method according to claim 3 wherein said detecting step and said delivering step are performed simultaneously.

5. A method for detecting monophasic action potentials and for supplying energy to ablate tissue within the heart comprising:

introducing a catheter having a distal end in a region of the heart, the distal end of the catheter carrying

first electrode means for contacting a tissue region for detecting monophasic action potentials in the contacted tissue region,

indifferent second electrode means for supplying a reference potential for the first electrode means and being carried on the catheter spaced from the first electrode means,

third electrode means between the first and second electrode means, the third electrode means being positioned close to the first electrode means, the third electrode means being operative for emitting energy to ablate the contacted tissue region, and

means for electrically insulating the third electrode means from the first and second electrode means,

bringing the first and third electrodes into contact with a tissue region within the heart,

operating the first electrode means to detect monophasic action potentials in the contacted tissue region,

operating the third electrode means to emit ablating energy to the contacted tissue region simultaneously with like operation of the first electrode means.

6. A method according to claim 5

wherein the steps of operating the first-and third electrode means are repeated until no monophasic action potentials are detected by the first electrode means.

7. A method for detecting monophasic action potentials and ablating tissue in the heart using a catheter having a distal end, with a first electrode carried at the distal end, a second electrode carried on a surface of the catheter and spaced from the first electrode, and a third electrode adjacent to but electrically insulated from the first electrode, including the steps of:

inserting the distal end into the heart;

positioning the distal end in a substantially perpendicular configuration against the endocardium of the heart such that the first electrode contacts the endocardium with a force sufficient to depolarize myocardial cells in the vicinity of the first electrode and such that the second electrode does not contact said endocardium;

detecting first signals by means of the first and second electrodes, said first signals relating to the monophasic action potentials of the heart;

at about the same time as the detecting step is performed, delivering ablating energy to the heart by means of the third electrode, and

repeating the detecting and delivering steps until no monophasic action potential signals are detected.

8. A method according to claim 7 wherein the detecting step and the delivering step are performed simultaneously.