Method for checking the operation of sensors situated in a dialysis liquid circuit

• US 5,399,157 A
• Filed: 07/06/1993
• Issued: 03/21/1995
• Est. Priority Date: 07/06/1992
• Status: Expired due to Term

• Current Assignee: Industries Gambro
• Original Assignee: Hospal Industrie
• Inventors: Goux, Nicolas, Bene, Bernard
• Primary Examiner(s): PREBILIC, PAUL B
• Application Number:
  US08/085,932
• Time in Patent Office: 623 Days
• Field of Search: 604/4, 604/5, 604/8, 604/9, 604/29, 604/52, 604/93, 604/175, 604/236, 604/256, 324/439, 324/555, 128/691, 128/692
• US Class Current: 604/4.01
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/1607 before use, i.e. upstream of dialyser
• CPC Class Codes: A61M 1/1609 after use, i.e. downstream of dialyser
• CPC Class Codes: A61M 1/165 with a dialyser bypass on the dialysis fluid line
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 PH measuring means
• CPC Class Codes: A61M 2205/70 with testing or calibration facilities

Abstract

The invention is a method for checking the operation of at least one sensor situated in a dialysis liquid circuit of an artificial kidney. The method includes causing a reference liquid of known characteristics to circulate in the extracorporeal blood circuit, taking a measurement to check at least one characteristic of the dialysis liquid by means of the sensor, calculating the theoretical value of at least one characteristic of the reference liquid on the basis of the measurement, comparing the calculated theoretical value with the known value of the said characteristic of the reference liquid, concluding that the sensor is working properly after the measurement has been taken when the calculated theoretical value is substantially equal to the known value. A device for the application of this method is also disclosed.

Claims

1. A method for checking operation of at least one sensor situated in a dialysis liquid circuit of an artificial kidney, the artificial kidney including an exchanger with two compartments separated by a semi-permeable membrane, one compartment being connected to the dialysis liquid circuit while another compartment is intended to be connected to an extracorporeal blood circuit, the method comprising the steps of:

circulating a noncorporeal reference liquid having a known characteristic value in the extracorporeal blood circuit;

circulating a dialysis liquid in the dialysis liquid circuit and measuring a first value upstream and downstream from the exchanger;

varying a composition of the dialysis liquid, and measuring a second value upstream and downstream from the exchanger for the varied composition;

calculating a characteristic value of the reference liquid on the basis of said first and second values;

comparing the calculated characteristic value with the known characteristic value of the reference liquid; and

determining that said sensor is functioning properly when the calculated characteristic value is substantially equal to the known characteristic value.

2. The method according to claim 1, wherein the reference liquid is a sterile solution.

8. The method according to claim 1, wherein the artificial kidney further comprises means for warning the operator when the calculated characteristic value is not substantially equal to the known characteristic value and wherein the operator is warned by the means for warning.

9. The method according to claim 1, further comprising circulating the dialysis liquid inside the exchanger until the dialysis liquid is in equilibrium with the reference liquid, and performing said measuring step when the equilibrium is reached.

10. The method according to claim 8, further comprising circulating the dialysis liquid inside the exchanger until the dialysis liquid is in equilibrium with the reference liquid, and performing said measuring step when the equilibrium is reached.

11. The method according to claim 1, further comprising varying a composition of the dialysis liquid, and measuring the value of the said characteristic upstream and downstream from the exchanger for each varied composition.

12. The method according to claim 8, further comprising varying a composition of the dialysis liquid, and measuring the value of the said characteristic upstream and downstream from the exchanger for each varied composition.

13. The method according to claim 1, wherein the step of measuring includes measuring a conductivity of the dialysis liquid.

14. The method according to claim 8, wherein the step of measuring includes measuring a conductivity of the dialysis liquid.

15. The method according to claim 9, wherein the step of measuring includes measuring a conductivity of the dialysis liquid.

16. The method according to claim 1, wherein the reference liquid is a sterile physiological serum solution.

17. The method according to claim 8, wherein the reference liquid is a sterile physiological serum solution.

18. The method according to claim 9, wherein the reference liquid is a sterile physiological serum solution.

19. The method according to claim 1, further comprising beginning the step of circulating a non-corporeal reference liquid when the exchanger is in a rinsing and priming stage.

20. The method according to claim 8, further comprising beginning the step of circulating a non-corporeal reference liquid when the exchanger is in a rinsing and priming stage.

21. The method according to claim 9, further comprising beginning the step of circulating a non-corporeal reference liquid when the exchanger is in a rinsing and priming stage.

3. A method for checking operation of at least one sensor situated in a dialysis liquid circuit of an artificial kidney, the artificial kidney including an exchanger with two compartments separated by a semi-permeable membrane, one compartment being connected to the dialysis liquid circuit while another compartment is intended to be connected to an extracorporeal blood circuit, the method comprising the steps of:

circulating a noncorporeal reference liquid having a known characteristic value in the extracorporeal blood circuit;

circulating a determined quantity of a dialysis liquid inside the exchanger until the dialysis liquid is in equilibrium with the reference liquid for at least one characteristic;

measuring at least one characteristic value of a dialysis liquid by means of at least one sensor;

comparing the measured characteristic value with the known characteristic value of the reference liquid; and

determining that said sensor is functioning properly when the measured characteristic value is substantially equal to the known characteristic value.

4. The method according to claim 3, wherein the artificial kidney further comprises means for warning the operator when the calculated characteristic value is not substantially equal to the known characteristic value and wherein the operator is warned by the means for warning.

5. The method according to claim 3, wherein the step of measuring includes measuring a conductivity of the dialysis liquid.

6. The method according to claim 3, wherein the reference liquid is a sterile solution.

7. The method according to claim 3, further comprising beginning the step of circulating a non-corporeal reference liquid when the exchanger is in a rinsing and priming stage.