Neuroprotective drug

• US 5,399,571 A
• Filed: 02/12/1993
• Issued: 03/21/1995
• Est. Priority Date: 02/25/1992
• Status: Expired due to Fees

• Current Assignee: Kanebo, Ltd. (HOYU Company Limited)
• Original Assignee: Kanebo, Ltd. (HOYU Company Limited)
• Inventors: Yamashita, Akira, Ito, Keizo, Yamamoto, Noriko, Yokota, Koichi
• Primary Examiner(s): Henley, III, Raymond
• Assistant Examiner(s): WEDDINGTON, KEVIN E
• Application Number:
  US08/016,860
• Time in Patent Office: 767 Days
• Field of Search: 514/365, 514/822
• US Class Current: 514/365
• CPC Class Codes: A61K 31/425 Thiazoles
• CPC Class Codes: A61P 25/28 for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

A neuroprotecting drug comprises as an essential active ingredient ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]pyrrol-1-yl acetate, which is useful with high safety for the prophylaxis and treatment of brain dysfunction induced by hypoxia due to the disturbance of cerebral circulation such as cerebral hemorrhage or cerebral infarction in human being.

Claims

1. A method for the treatment of brain dysfunction induced by hypoxia due to the disturbance of cerebral circulation, which comprises administering orally about 2 to 100 mg per day of ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]pyrrol-1-yl acetate to a patient suffering from the disturbance of cerebral circulation.

2. A method for the treatment of brain dysfunction induced by hypoxia due to cerebral hemorrhage or cerebral infarction, which comprises administering orally about 2 to 100 mg per day of ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]pyrrol-1-yl acetate to a patient suffering from the cerebral hemorrhage or cerebral infarction.