DNA complexes with dyes designed for energy transfer as fluorescent markers
First Claim
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1. A fluorescent heteromultimer which is thiazole orange-thiazole blue dimer of formula 7 of FIG. 2.
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Abstract
Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.
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2 Claims
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1. A fluorescent heteromultimer which is thiazole orange-thiazole blue dimer of formula 7 of FIG. 2.
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2. A fluorescent heteromultimer which is thiazole orange-ethidium dimer of formula 11 of FIG. 3.
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