Medical devices having an electrically conductive hydrogel coating

• US 5,403,295 A
• Filed: 10/26/1993
• Issued: 04/04/1995
• Est. Priority Date: 05/13/1991
• Status: Expired due to Fees

• Current Assignee: British Technology Group Ltd.
• Original Assignee: British Technology Group Ltd.
• Inventors: Byrne, Phillip O.
• Primary Examiner(s): Yasko, John D.
• Assistant Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US08/137,192
• Time in Patent Office: 525 Days
• Field of Search: 604/264, 604/265, 604/280, 604/20, 604/53, 604/266, 128/640, 128/798
• US Class Current: 604/265
• CPC Class Codes: A61L 29/145 Hydrogels or hydrocolloids
• CPC Class Codes: A61M 25/0017 specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
• CPC Class Codes: A61M 25/0045 multi-layered, e.g. coated coating materials A61L29/08

Abstract

A medical device, such as a catheter (10), for location at least partially within a patient'"'"'s body for a period of at least the order of a day, includes an electrode (11) connected in an electrical circuit (11,12,13) operable to generate by way of the electrode an electric field to inhibit bacterial attachment and colonization on and adjacent to the device/body interface, and the electrode includes an electrically conductive hydrogel coating (11) to define the device/body interface. The coating can be loaded with a salt to ensure conductivity and pH material to stabilize the surrounding hydrogen ion concentration in use of the device.

Claims

1. A medical device for location partially within a patient'"'"'s body for a period of at least the order of a day, said device comprising an electrode connectable with an electrical circuit operable to generate by way of said electrode an electric field acting in use of the device to inhibit bacterial attachment and colonization on and adjacent to the device/body interface, said electrode comprising a hydrogel coating to define said interface, said hydrogel coating being loaded with a salt to ensure conductivity with substantially predictable electrical properties, said hydrogel coating being dehydrated prior to use and requiring rehydration as a preliminary to use.

2. A device according to claim 1, wherein said electrode is connected to a said electrical circuit.

3. A device according to claim 1, which is made of a plastics material.

4. A device according to claim 1, wherein said hydrogel coating is loaded with pH buffer material to stabilize the hydrogen concentration around said coating during use.

5. A device according to claim 1 in the form of a catheter or like tubular device having said hydrogel coating around an end portion thereof intended for location in a patient.

6. A device according to claim 5 and including circumferentially partway therealong an annular terminal electrode having an elongate electrical connector lead extending therefrom, said annular electrode being at least partially superimposed by said hydrogel coating in electrically conductive engagement therewith.

7. A combination comprising a device according to claim 1 and separate material for incorporation into said device by way of an associated rehydration liquid for said hydrogel coating, said separate material including at least one of a salt to ensure conductivity with substantially predictable electrical properties for said hydrogel coating and a pH buffer for stabilizing the hydrogen ion concentration around said hydrogel coating during use.

8. A combination according to claim 7, wherein said salt is selected from the group consisting of sodium chloride and potassium chloride.