Removable and pierceable activation closure for two-compartment vial

• US 5,405,001 A
• Filed: 04/29/1994
• Issued: 04/11/1995
• Est. Priority Date: 04/29/1994
• Status: Expired due to Fees

• Current Assignee: Glory & Blessing Corporation
• Original Assignee: Clinetics Corporation
• Inventors: Lillard, Jeffrey L.
• Primary Examiner(s): ACKUN, JACOB K
• Application Number:
  US08/235,551
• Time in Patent Office: 347 Days
• Field of Search: 206/219, 206/221, 215/6, 215/DIG. 8, 215/354, 215/355, 215/320, 220/212, 220/306, 220/307, 220/315
• US Class Current: 206/221
• CPC Class Codes: B65D 25/082 the partition being in the form of a plug or the like which is removed by increasing or decreasing the pressure within the container B65D81/3211 takes precedence
• CPC Class Codes: B65D 41/58 Caps or cap-like covers combined with stoppers
• CPC Class Codes: B65D 51/002 Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
• CPC Class Codes: Y10S 215/08 Mixing

Abstract

A closure structure or cap for a two compartment vial includes a resilient stopper having a cylindrical body with a lower shoulder portion adapted for sealing fit in the mouth of the vial and a second circumferential shoulder at is upper end. A substantially rigid hollow cylindrical sleeve is configured to surround the mouth of the vial, and has, at its upper end, integrally constructed downwardly projecting longitudinally split fingers dimensioned to embrace the stopper, with the bottoms of the split fingers engaging and resting upon the lower shoulder portion of the rubber stopper. An internal groove in the split fingers engages the lower edge of a second shoulder of the stopper thereby gripping the stopper. A locking member is disposed between the longitudinally split fingers and the inside walls of the hollow cylindrical sleeve or cap, forming means to prevent spreading of the fingers and thereby preventing the loosening of the grip of the fingers on the stopper. The cylindrical sleeve is of such length that its lower end extends below the bottom of the stopper, whereby when the closure is removed from the vial and is placed on a support surface only the lower end of the sleeve rests on the surface. Optionally, the locking member includes a frangible tab which, after removal exposes the upper surface of the resilient stopper for puncturing with a hypodermic needle, thereby permitting removal of liquid from the vial with a needle and syringe.

Claims

1. In combination a two-compartment vial having a lower first compartment and an upper second compartment, said compartments being separated from each other with a neck portion having a plug which acts as a dislodgeable seal, and a mouth portion above the second compartment, and an activation closure cap which comprises:

a resilient stopper having a substantially cylindrical main body, a first lower shoulder portion concentric with the main body and dimensioned to sealingly fit within the mouth of the vial, and a second upper shoulder portion concentric with the main body;

a hollow substantially cylindrical sleeve of larger diameter than the mouth of the vial, configured to be placed around the mouth of the vial, the sleeve including a plurality of fingers disposed substantially axially within its interior, an annular space being formed between the fingers and the inner wall of the cylindrical sleeve, the fingers forming a cylinder with split walls and dimensioned to receive the upper shoulder and the main body of the stopper in a configuration where the lower ends of the fingers abut the lower shoulder of the stopper, and

locking means attached to the sleeve for preventing the fingers from spreading outwardly into the annular space, thereby causing the fingers to firmly grip the resilient stopper, the sleeve being of such dimension that it extends below the bottom of the resilient stopper when the stopper is gripped in the fingers, whereby the activation closure cap can be removed from the vial without leaving the stopper in the mouth of the vial, and whereby when the closure cap is removed from the vial and placed on a flat support surface only the bottom of the sleeve touches the support surface.

2. The combination of claim 1 wherein the stopper comprises medicinal grade rubber.

3. The combination of claim 1 wherein the sleeve further includes within its interior a plurality of circumferentially spaced radially inwardly pointing tabs, and wherein each finger is attached to one of the tabs.

4. The combination of claim 1 wherein each finger has a step-down portion, said step-down portions forming means for engaging the upper shoulder of the resilient stopper.

5. The combination of claim 1 wherein the locking means comprise a disk having a plurality of downwardly projecting spikes configured to tightly fit in the annular space between the fingers and the interior wall of the sleeve.

6. The combination of claim 1 wherein the locking means comprise a disk having a plurality of downwardly projecting spikes configured to tightly fit in the annular space between the fingers and the interior wall of the sleeve, a center portion of the disk being disposed above the resilient stopper and being frangibly attached to the disk so that when the frangible portion is severed the center portion is removed and the top of the resilient stopper is exposed.

7. The combination of claim 6 wherein the locking means and the sleeve are dimensioned such in relation to the vial that the lower end of the spikes abutting the mouth of the vial comprise the lower limit of travel of the closure cap downward on the vial.

8. The combination of claim 1 wherein the sleeve and the fingers comprise one unitary piece.

9. In combination a two-compartment vial having a lower first compartment and an upper second compartment, said compartments being separated from each other with a neck portion narrower than either of the first and second compartments and having a plug which acts as a dislodgeable seal, and a mouth portion above the second compartment concentric with and narrower than the second compartment, and an activation closure cap which comprises:

a resilient stopper having a substantially cylindrical main body, a first lower shoulder portion larger in diameter than and concentric with the main body and dimensioned to sealingly fit within the mouth of the vial, and a second upper shoulder portion larger in diameter than and concentric with the main body;

a hollow substantially cylindrical sleeve of larger diameter than the mouth of the vial, configured to fit about the mouth of the vial, the sleeve including a plurality of fingers disposed substantially axially within its interior, an annular space being formed between the fingers and the inner wall of the cylindrical sleeve, the fingers forming a cylinder with split walls dimensioned to receive and hold the upper shoulder and the main body of the stopper in a configuration where the fingers are juxtaposed to the upper shoulder and to the main body of the stopper and the lower ends of the fingers abut the lower shoulder of the stopper, and

locking means attached to the sleeve for preventing the fingers from spreading outwardly into the annular space, thereby causing the fingers to firmly grip the resilient stopper, the sleeve being of such dimension that it extends below the bottom of the resilient stopper when the stopper is held in the fingers.

10. The combination of claim 9 wherein the stopper comprises medicinal grade rubber.

11. The combination of claim 10 wherein the sleeve further includes within its interior a plurality of circumferentially spaced radially inwardly pointing tabs, and wherein each finger is attached to one of the tabs.

12. The combination of claim 11 wherein each finger has a step down portion, said step down portions forming means for engaging the upper shoulder of the resilient stopper.

13. The combination of claim 12 wherein the locking means comprise a disk having a plurality of downwardly projecting spikes configured to tightly fit in the annular space between the fingers and the interior wall of the sleeve.

14. The combination of claim 13 wherein the disk of the locking means includes a center portion disposed above the resilient stopper and being frangibly attached to the disk so that when the frangible portion is severed the center portion is removed and the top of the resilient stopper is exposed.

15. The combination of claim 14 wherein the sleeve and the fingers comprise one unitary piece.

16. An activation closure cap in combination with a two compartment vial adapted to seal the two-compartment vial of the type having a lower first compartment and an upper second compartment, said compartments being separated from each other with a neck portion having a plug which acts as a dislodgeable seal, and a mouth portion above the second compartment, the closure cap comprising:

a resilient stopper configured to fit within and seal the mouth of the vial;

a hollow cylindrical sleeve configured to fit around the mouth of the vial and capable of being moved in the ordinary course of operating the combination, within limits, axially down on the mouth of the vial and without limit axially up on the vial whereby pressure can be exerted on liquid contained in the upper compartment by pushing the closure cap downward on the vial to dislodge the plug, the sleeve including means for firmly gripping the resilient stopper while the sleeve moves axially UP on the mouth of the vial and for carrying the stopper with the sleeve, whereby the closure cap including the resilient stopper can be removed from the vial.

17. The combination of claim 16 wherein the sleeve and the stopper are dimensioned such that the lower end of the sleeve is disposed below the lower end of the stopper, whereby when the closure cap is removed from the vial and is placed in an upright position on a support surface the stopper does not touch the support surface.

18. An activation closure cap adapted to seal a two-compartment vial of the type having a lower first compartment and an upper second compartment, said compartments being separated from each other with a neck portion having a plug which acts as a dislodgeable seal, and a mouth portion above the second compartment, the closure cap comprising:

a resilient stopper configured to fit within and seal the mouth of the vial;

a hollow cylindrical sleeve configured to fit around the mouth of the vial and capable of being moved, within limits, axially up and down on the mouth of the vial whereby pressure can be exerted on liquid contained in the upper compartment by pushing the closure cap downward on the vial to dislodge the plug, the sleeve including means for firmly gripping the resilient stopper, whereby the closure cap including the resilient stopper can be removed from the vial, the means for firmly gripping the resilient stopper comprising a plurality of fingers disposed substantially axially within the interior of the cylindrical sleeve, an annular space being formed between the fingers and the inner wall of the cylindrical sleeve, the fingers forming a cylinder with split walls wherein the resilient stopper is held, the means for firmly gripping the resilient stopper further comprising locking means attached to the sleeve for preventing the fingers from spreading outwardly into the annular space.

19. The activation closure cap of claim 18 wherein the sleeve further includes within its interior a plurality of circumferentially spaced radially inwardly pointing tabs, and wherein each finger is attached to one of the tabs.

20. The activation closure cap of claim 19 wherein the locking means comprise a disk having a plurality of downwardly projecting spikes configured to tightly fit in the annular space between the fingers and the interior wall of the sleeve.

21. The activation closure cap of claim 20 wherein the sleeve, the tabs and the fingers comprise one unitary piece.