Method of highlighting intagliations in tablets

• US 5,405,642 A
• Filed: 07/30/1993
• Issued: 04/11/1995
• Est. Priority Date: 02/27/1991
• Status: Expired due to Term

• Current Assignee: Janssen Pharmaceutica NV (Johnson & Johnson)
• Original Assignee: Janssen Pharmaceutica NV (Johnson & Johnson)
• Inventors: Gilis, Paul M. V., De Conde, Valentin F. V.
• Primary Examiner(s): Beck, Shrive
• Assistant Examiner(s): CAMERON, ERMA C
• Application Number:
  US08/094,137
• Time in Patent Office: 620 Days
• Field of Search: 427/3, 424/467, 424/476
• US Class Current: 427/2.23
• CPC Class Codes: A61K 9/2072 characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms A61K9/0004, A61K9/0056, A61K9/0065 take precedence

Abstract

A method of highlighting intagliations in white or colored coated tablets by spraying onto said tablets a suspension comprising a filling material having a different color, a waxy material and a solvent, and removing the solvent and the excess of filling material and waxy material.

Claims

1. A method of highlighting intagliations in white or colored coated tablets, characterized by (a) spraying onto said tablets a suspension comprising a filling material having a different color than the surface of said coated tablets, a waxy material and a solvent, (b) removing the solvent, and (c) removing the excess of filling material and waxy material from the entire surface of said tablets except for the intagliations.

2. A method according to claim 1 wherein the filling material is corn starch or microcrystalline cellulose.

3. A method according to claim 2 wherein the filling material is previously dyed with an edible lake pigment.

4. A method according to claim 1 wherein the amount of solvent in the suspension ranges from 70% to 85%.

5. A method according to claim 1 wherein the solvent and the excess of filling material and waxy material are removed by blowing off with air and keeping the tablets tumbling.

6. A method according to claim 1 wherein the waxy material is a polyethylene glycol.

7. A method according to claim 2 wherein the waxy material is a polyethylene glycol.

8. A method according to claim 3 wherein the waxy material is a polyethylene glycol.

9. A method according to claim 6 wherein the weight to weight ratio of waxy material to filling material ranges from 1:

3 to 1;

12.

10. A method according to claim 7 wherein the weight to weight ratio of waxy material to filling material ranges from 1:

3 to 1;

12.

11. A method according to claim 8 wherein the weight to weight ratio of waxy material to filling material ranges from 1:

3 to 1;

12.

12. A method according to claim 1 wherein the solvent does not dissolve the filling material.

13. A method according to claim 2 wherein the solvent does not dissolve the filling material.

14. A method according to claim 3 wherein the solvent does not dissolve the filling material or the dye.

15. A method according to claim 1 wherein the tablets containing the filling material in the intagliations are provided with a further coating film.

16. A tablet produced by the method of claim 1.