Method and apparatus to reduce injury to the vascular system

• US 5,409,444 A
• Filed: 03/04/1992
• Issued: 04/25/1995
• Est. Priority Date: 03/04/1992
• Status: Expired due to Fees

• Current Assignee: Kensey Nash Corporation (DSM-Firmenich AG)
• Original Assignee: Kensey Nash Corporation (DSM-Firmenich AG)
• Inventors: Nash, John, Kensey, Kenneth
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US07/845,886
• Time in Patent Office: 1,147 Days
• Field of Search: 600/16, 600/17, 600/18, 623/3
• US Class Current: 600/18
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61M 25/04 in the body, e.g. expansible A61M25/10, A61M16/0488 take precedence

Abstract

An apparatus and method for reducing peak systolic blood pressure and the rate of change of velocity of the blood flow in a living being by passively absorbing a portion of the blood pressure during systole. The apparatus comprises an expandable/contractible chamber, e.g., a balloon, which is internally pressurized by a gas, e.g., carbon dioxide. The chamber has a surface portion which is moveable between first and second positions and vice versa when the chamber is contracted and expanded, respectively. The chamber is sufficiently small to be located at a desired situs, such as the aorta, so that the surface portion is subjected to blood pressure, whereupon it moves to the second position during systole to reduce the magnitude thereof while also reducing the rate of change of the velocity of the blood flow. The chamber expands so that the surface portion automatically returns to the first position to release an absorbed portion of the blood pressure during diastole, all the while maintaining average blood flow and pressure. A releasable anchoring mechanism is provided to hold the chamber in place within the patient'"'"'s body.

Claims

1. A method of reducing the magnitude of systolic blood pressure of a living being by the use of passive pressure absorption means comprising a first chamber having a gas therein pressurizing said chamber to a predetermined internal pressure, said chamber being expandable to an expanded state and contractible to a contracted state, and vice versa, said method comprising locating said first chamber within the body of said being at a desired situs to subject said first chamber to the being'"'"'s blood pressure, whereupon during systole said first chamber contracts from said expanded state to said contracted state to thereby reduce the magnitude of the systolic pressure, said first chamber expanding to said expanded stated during diastole, whereupon said first chamber releases an absorbed portion of said systolic blood pressure.

2. The method of claim 1 wherein said gas is introduced into said first chamber after said passive pressure absorption means is located within the body of said being.

3. The method of claim 1 wherein said first portion is located within the aorta.

4. The method of claim 1 additionally comprising providing a second chamber in fluid communication with said first chamber.

5. The method of claim 4 wherein said second chamber is of a predetermined volumetric capacity.

6. The method of claim 5 wherein said predetermined volumetric capacity is fixed.

7. The method of claim 5 wherein said predetermined volumetric capacity is variable.

8. The method of claim 4 wherein said second chamber is located remote from said first chamber.

9. The method of claim 8 wherein said second chamber is located outside of the body of said being.

10. The method of claim 8 wherein said second chamber is located within the body of said being.

11. The method of claim 1 wherein a portion of said apparatus is made radiographic to facilitate the location of said first portion at said situs within the body of said being.

12. The method of claim 1 wherein said first chamber is located within said vascular system and wherein said method additionally comprises providing a second chamber in fluid communication with said first chamber, said second chamber being located externally of said vascular system.

13. The method of claim 12 wherein said second chamber is located outside the body of said being.

14. A method of reducing the magnitude of systolic blood pressure of a living being by the use of passive pressure absorption means comprising a first chamber and a second chamber in fluid communication with each other, said first chamber having a gas therein and being expandable to an expanded state and contractible to a contracted state, and vice versa, said method comprising locating said second chamber outside the body of said being, locating said first chamber within the body of said being at a desired situs to subject said first chamber to the being'"'"'s blood pressure, whereupon during systole said first chamber contracts from said expanded state to said contracted state to thereby reduce the magnitude of the systolic pressure, said first chamber expanding to said expanded stated during diastole, whereupon said chamber releases an absorbed portion of said systolic blood pressure.

15. A method of reducing the magnitude of the change in velocity of the flow of blood in a living being by the use of passive means comprising a first chamber having a gas therein pressurizing said chamber to a predetermined internal pressure, said chamber being expandable to an expanded state and contractible to a contracted state, and vice versa, said method comprising locating said first chamber within the body of said being at a desired situs to subject said first chamber to the being'"'"'s blood flow, whereupon during systole said first chamber contracts from said expanded state to said contracted state to thereby reduce the magnitude of the change in velocity of said blood, said first chamber expanding to said expanded state during diastole.

16. The method of claim 15 wherein said gas is introduced into said first chamber after said passive means is located within the body of said being.

17. The method of claim 15 wherein said first chamber is located within the aorta.

18. The method of claim 15 additionally comprising providing a second chamber in fluid communication with said first chamber.

19. The method of claim 18 wherein said second chamber is of a predetermined volumetric capacity.

20. The method of claim 19 wherein said predetermined volumetric capacity is fixed.

21. The method of claim 19 wherein said predetermined volumetric capacity is variable.

22. The method of claim 18 wherein said second chamber is located remote from said first chamber.

23. The method of claim 22 wherein said second chamber is located within the body of said being.

24. The method of claim 15 wherein a portion of said apparatus is made radiographic to facilitate the location of said first portion at said situs within the body of said being.

25. The method of claim 15 wherein said first chamber is located within said vascular system and wherein said method additionally comprises providing a second chamber in fluid communication with said first chamber, said second chamber being located externally of said vascular system.

26. The method of claim 25 wherein said second chamber is located outside the body of said being.

27. A method of reducing the magnitude of the change in velocity of the flow of blood in a living being by the use of passive means comprising a first chamber and a second chamber in fluid communication with each other, said first chamber having a gas therein and being expandable to an expanded state and contractible to a contracted state, and vice versa, said method comprising locating said second chamber outside the body of said being, locating said first chamber within the body of said being at a desired situs to subject said first chamber to the being'"'"'s blood flow, whereupon during systole said first chamber contracts from said expanded state to said contracted state to thereby reduce the magnitude of the change in velocity of said blood, said first chamber expanding to said expanded stated during diastole.

28. An apparatus for reducing the magnitude of systolic blood pressure in the cardiovascular system of a living being, said apparatus comprising passive pressure absorption means, said passive pressure absorption means comprising a first chamber means having a gas therein which is pressurized to a predetermined internal pressure, said chamber means for expansion and contraction when subjected to the being'"'"'s blood pressure, said first chamber means being arranged to be located at a desired situs within the body of said being so that said first chamber is subjected to the being'"'"'s blood pressure, whereupon the first chamber means contracts to a contracted state by said blood pressure during systole to reduce the magnitude of systolic pressure, and expands to an expanded state during diastole.

29. The apparatus of claim 28 wherein said first chamber means is arranged to automatically return to said expanded state to release an absorbed portion of the blood pressure during diastole.

30. The apparatus of claim 28 wherein said first chamber means comprises an inflatable balloon.

31. The apparatus of claim 30 wherein the material forming said balloon is inextensible.

32. The apparatus of claim 30 additionally comprising a second chamber means in fluid communication with said first chamber means.

33. The apparatus of claim 32 wherein said second chamber means is of a predetermined volumetric capacity.

34. The apparatus of claim 33 wherein said second chamber means is of a variable volumetric capacity.

35. The apparatus of claim 33 wherein said second chamber means is of a fixed volumetric capacity.

36. The apparatus of claim 28 additionally comprising a second chamber means in fluid communication with said first chamber means.

37. The apparatus of claim 36 wherein said second chamber means is of a predetermined volumetric capacity.

38. The apparatus of claim 37 wherein said second chamber means is of a fixed volumetric capacity.

39. The apparatus of claim 38 wherein said second chamber means is of a variable volumetric capacity.

40. The apparatus of claim 39 wherein said second chamber is arranged to be located outside the body of said being.

41. The apparatus of claim 38 wherein said second chamber is arranged to be located outside the body of said being.

42. The apparatus of claim 28 additionally comprising anchoring means for anchoring said first chamber means at said situs.

43. The apparatus of claim 42 wherein said anchoring means is releasably securable to said situs.

44. The apparatus of claim 28 wherein said first chamber means is configured for location within said vascular system and wherein said passive pressure absorption means additionally comprises a second chamber means in fluid communication with said first chamber means, said second chamber means being arranged for location externally of said vascular system.

45. The apparatus of claim 44 wherein said second chamber means is arranged for location outside the body of said being.

46. An apparatus for reducing the magnitude of the change in velocity of blood flow in a living being, said apparatus comprising first chamber means for expansion and contraction when subjected to said being'"'"'s blood pressure and having a gas therein which is pressurized to a predetermined internal pressure, said first chamber means being arranged to be located at a desired situs within the body of said being so that said first chamber means is subjected to the being'"'"'s blood flow, whereupon said first chamber means contracts to a contracted state by said blood flow during systole to thereby reduce the magnitude of the change in its velocity, said first chamber means expanding to an expanded stated during diastole.

47. The apparatus of claim 46 wherein said first chamber means comprises an inflatable balloon,

48. The apparatus of claim 47 wherein the material forming said balloon is inextensible.

49. The apparatus of claim 46 additionally comprising a second chamber means in fluid communication with said first chamber,

50. The apparatus of claim 49 wherein said second chamber means is of a predetermined volumetric capacity,

51. The apparatus of claim 50 wherein said second chamber means is of a fixed volumetric capacity,

52. The apparatus of claim 51 wherein said second chamber is arranged to be located outside the body of said being.

53. The apparatus of claim 50 wherein said second chamber means is of a variable volumetric capacity,

54. The apparatus of claim 53 wherein said second chamber is arranged to be located outside the body of said being.

55. The apparatus of claim 46 additionally comprising anchoring means for anchoring said first chamber means at said situs,

56. The apparatus of claim 55 wherein said anchoring means is releasably securable to said situs.

57. The apparatus of claim 46 wherein said first chamber means is configured for location within said vascular system and wherein said passive pressure absorption means additionally comprises a second chamber means in fluid communication with said first chamber means, said second chamber being arranged for location externally of said vascular system.

58. The apparatus of claim 57 wherein said second chamber means is arranged for location outside the body of said being.

59. An apparatus for reducing the magnitude of systolic blood pressure in the cardiovascular system of a living being, said apparatus comprising passive pressure absorption means, said passive pressure absorption means comprising a first chamber means and a second chamber means in fluid communication with each other, said second chamber means being arranged to be located outside the body of said being, said first chamber means for expansion and contraction when subjected to the being'"'"'s blood pressure and having a gas therein, said first chamber means being arranged to be located at a desired situs within the body of said being so that said first chamber means is subjected to the being'"'"'s blood pressure, whereupon the first chamber means contracts to a contracted state by said blood pressure during systole to reduce the magnitude of systolic pressure and expands to an expanded state during diastole.

60. An apparatus for reducing the magnitude of the change in velocity of blood flow in a living being, said apparatus comprising a first chamber means and a second chamber means in fluid communication with each other, said second chamber means being arranged for location outside the body of said being, said first chamber means for expansion and contraction when subjected to said being'"'"'s blood pressure and having a gas therein, said first chamber means being arranged for location at a desired situs within the body of said being so that said first chamber means is subjected to the being'"'"'s blood flow, whereupon the first chamber means contracts to a contracted state by said blood flow during systole to thereby reduce the magnitude of the change in its velocity and expands to an expanded state during diastole.