Directly visualized method for deploying a detachable balloon at a target site in vivo

• US 5,411,475 A
• Filed: 04/28/1993
• Issued: 05/02/1995
• Est. Priority Date: 10/24/1991
• Status: Expired due to Fees

• Current Assignee: Cystomedix, Inc.
• Original Assignee: Children's Medical Center Corporation
• Inventors: Mandell, James, Atala, Anthony
• Primary Examiner(s): YAN, REN LUO
• Application Number:
  US08/054,375
• Time in Patent Office: 734 Days
• Field of Search: 606/108, 606/192, 606/194, 606/191, 606/195, 604/96, 604/54, 623/1, 623/12, 128/898
• US Class Current: 604/96.01
• CPC Class Codes: A61B 17/12099 characterised by the location of the occluder
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61M 2025/1054 having detachable or disposable balloons

Abstract

A directly visualized method for deploying a detachable balloon to a target site in vivo is described. The method allows a physician or technician to deploy the detachable balloon to the target site while directly visualizing the detachment of the balloon and/or the effects of the detached balloon on the target site in vivo. The present invention alleviates problems associated with the use of indirect visualization techniques conventionally used for deploying such detachable balloons. The directly, visualized method of this invention includes the steps of providing a scope capable of directly visualizing a target site in vivo, passing a balloon catheter including an uninflated, detachable balloon through the lumen of a positioning element of the scope, and inflating and detaching the balloon at the target site in vivo.

Claims

1. A directly, visualized method for deploying a detachable balloon to a target site in vivo, comprising:

providing a scope for directly visualizing a target site in vivo, the scope comprising a sheath a viewing means for viewing the target site and a positioning element extending longitudinally through the sheath;

passing an uninflated, detachable balloon attached to a catheter through a lumen of a positioning element of the scope to a target site in vivo; and

inflating and detaching the balloon at the target site in vivo while directly visualizing the detachment of the balloon and/or the effects of the detached balloon on the target site in vivo.

2. The method of claim 1 wherein the positioning element is a hypodermic needle.

3. The method of claim 1 wherein the lumen of the positioning element has an inside diameter of less than about 0.036 inches.

4. The method of claim 1 wherein the detachable balloon is inflated with a biocompatible material.

5. The method of claim 1 wherein the detachable balloon is inflated with a polymerizable solution which gels or solidifies in vivo.

6. The method of claim 1 wherein the target site in vivo in the passing step is selected such that the detached, inflated balloon provides occlusive pressure to a duct.

7. The method of claim 1 wherein the target site in vivo in the passing step is selected such that the detached, inflated balloon provides blockage within a duct.

8. The method of claim 7 where the blockage within the duct is complete blockage.

9. The method of claim 1 wherein the target site in vivo in the passing step is the subureteral region of a reflux-prone bladder.

10. The method of claim 1 wherein the target site in vivo in the passing step is selected to cause blockage or closure of fallopian tubes in a female subject.

11. The method of claim 1 wherein the target site in vivo in the passing step is between the urethra and the subcutaneous corpus spongiousum.

12. The method of claim 1 wherein the target site in vivo in the passing step is selected to cause blockage or closure of a duct involved in the delivery of sperm outside the body of a male subject.

13. A system for deploying a detachable balloon to a target site in vivo and directly visualizing the detached, inflated balloon and/or its effects in vivo, comprising:

a scope for directly visualizing a target site in vivo, the scope comprising a shealth, a viewing means for viewing a target site and a positioning element extending longitudinally through the sheath; and

a balloon catheter including a detachable, uninflated balloon, said detachable, uninflated balloon adapted for passage through a lumen of the positioning element of the scope.

14. The system of claim 13 wherein the positioning element of the scope is a hypodermic needle.

15. The system of claim 13 wherein the lumen of the positioning element of the scope has an inside diameter of less than about 0.036 inches.

16. The system of claim 13 wherein the scope includes an endoscope.

17. The system of claim 16 wherein the scope includes a cystoscope.

18. The system of claim 13 wherein the balloon catheter comprises a sealing means for sealing the balloon following inflation.

19. The system of claim 18 wherein the sealing means comprises a constrictive collar.

20. The system of claim 18 wherein the sealing means comprises a hip seal.

21. The system of claim 13 wherein the detachable balloon is a silicone rubber balloon.