Three-layer vascular prostheses
First Claim
1. An implantable three-layer vascular prosthesis comprising:
- a tanned, physically self-supporting, physiologically resorbable internal layer (1),a physiologically non-resorbable, porous middle layer (2),a tanned, physically self-supporting, physiologically resorbable external layer (3),wherein the internal layer and the external layer are made from a biological material and the tanning of the internal layer is to a greater extent than the tanning of the external layer whereby the external layer is resorbed faster than the internal layer after implantation into an organism.
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Abstract
The invention relates to three-layer vascular prostheses comprising an internal layer 1, a middle layer 2 and an external layer 3 which is characterized in that the middle layer 2 is made from a physiologically non-resorbable, porous material, and the internal layer 1 and the external layer 3 are self-supporting and are made from a physiologically resorbable, fibrillar material, and are tanned. The internal layer 1 and the external layer 3 preferably consist of collagen, but have different resorbability. The middle layer 2 is preferably made from inert fibers, preferably synthetic fibers, by means of textile technology. The biologically resorbable layers preferably comprise chemically or physically bonded or incorporated pharmacologically active substances.
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Citations
22 Claims
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1. An implantable three-layer vascular prosthesis comprising:
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a tanned, physically self-supporting, physiologically resorbable internal layer (1), a physiologically non-resorbable, porous middle layer (2), a tanned, physically self-supporting, physiologically resorbable external layer (3), wherein the internal layer and the external layer are made from a biological material and the tanning of the internal layer is to a greater extent than the tanning of the external layer whereby the external layer is resorbed faster than the internal layer after implantation into an organism. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method for manufacturing the prosthesis according to claim 25, comprising the following steps:
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(A) Preparing a self-supporting internal layer (1) from a physiologically resorbable fibrillar material, (B) tanning the internal layer (1) by means of a biologically acceptable tanning agent to reduce swelling capacity, (C) providing a middle layer (2) by applying a layer of a physiologically non-resorbable, porous material onto the internal layer (1), (D) providing an external layer (3) by applying a self-supporting layer of a physiologically resorbable fibrillar material onto the middle layer (2), and (E) tanning the external layer (3) by means of a biologically acceptable tanning agent to reduce swelling capacity. - View Dependent Claims (21, 22)
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Specification