Method and apparatus for sterilizing articles

• US 5,413,757 A
• Filed: 04/29/1991
• Issued: 05/09/1995
• Est. Priority Date: 04/21/1988
• Status: Expired due to Fees

• Current Assignee: Flexiclave, Inc.
• Original Assignee: Flexiclave, Inc.
• Inventors: Latowicki, Daniel A., Kutner, Barry S.
• Primary Examiner(s): McMahon, Timothy M.
• Application Number:
  US07/692,736
• Time in Patent Office: 1,471 Days
• Field of Search: 422/21, 422/294, 422/299, 219/10.55 E, 250/455.1, 426/107, 426/234, 426/243
• US Class Current: 422/21
• CPC Class Codes: A45C 11/005 Contact lens cases A45C11/046 takes precedence
• CPC Class Codes: A61L 2/20 Gaseous substances, e.g. vapours
• CPC Class Codes: B65D 2581/3489 Microwave reflector, i.e. microwave shield B65D2581/3487 takes precedence
• CPC Class Codes: B65D 2585/545 Contact lenses
• CPC Class Codes: B65D 81/3461 Flexible containers, e.g. bags, pouches, envelopes

Abstract

Method and apparatus for sterilizing articles including introducing the article and liquid solution into a collapsible pouch formed of vapor-impermeable sheet material, sealing the collapsible pouch to form a gas-tight assembly, and heating the gas-tight assembly to vaporize the liquid solution to produce an atmosphere of hot vapor. The liquid is introduced into the pouch in a quantity sufficient to create an overpressure when vaporized which is indicated by the collapsible pouch expanding to a distended condition. In one embodiment, the liquid solution is vaporized by irradiating the gas-tight assembly with microwave radiation. In other embodiments particularly suited for sterilizing a plurality of metallic articles, the at least one article is surrounded by shielding, which may be separate from or integrated with the pouch, which presents a barrier to the transmission of microwave radiation. The pouch containing the shielded article or articles and liquid solution is sealed and the gas-tight assembly is irradiated with microwave radiation to vaporize the liquid whereupon the article or articles are sterilized under the effect of vapor under pressure.

Claims

1. A method for sterilizing at least one article by vapor under pressure comprising the steps of:

providing an expandable pouch formed of flexible, vapor-impermeable sheet material, said expandable pouch existing in a collapsed condition in its normal state and having the ability to expand to a visually apparent substantially distended condition;

introducing at least one article to be sterilized into said pouch while said pouch is in said collapsed condition;

introducing a quantity of liquid into said pouch while said pouch is in said collapsed condition, said quantity of liquid being sufficient so that when said pouch is sealed to form a gas-tight assembly and said liquid is vaporized, an over-pressure is created within said pouch which will expand said pouch to said visually apparent substantially distended condition;

sealing said pouch to form a gas-tight assembly;

vaporizing said liquid to produce an atmosphere of hot vapor under pressure in said gas-tight assembly so that said pouch expands from said collapsed condition to said visually apparent substantially distended condition under the effect of said pressure; and

verifying that an atmosphere of hot vapor under pressure exists in said gas-tight assembly by utilizing the expansion of said pouch as an indication thereof;

whereby said at least one article situated within said gas-tight assembly is sterilized under the effect of vapor under pressure.

2. The method recited in claim 1 wherein said step of vaporizing said liquid comprises irradiating said gas-tight assembly with radiation.

3. The method recited in claim 2 wherein said radiation comprises microwave radiation, and including the additional step of shielding said at least one article in its entirety from said radiation during said vaporizing step.

4. The method recited in claim 1 including the preliminary step of constructing an expandable pouch by forming a section of a tubular web from a pair of overlying sheets of plastic material sealed at their longitudinal edge margins;

and sealing one of the ends of said tubular web section by fusing first narrow transversely extending regions of said overlying sheets proximate to said one of said ends to each other.

5. The method recited in claim 1 wherein said expandable pouch is formed of plastic sheet material and said step of sealing said pouch opening to form a gas-tight assembly comprises the step of fusing narrow transversely extending regions of overlying portions of said pouch to each other.

6. The method recited in claim 1 wherein said expandable pouch has an interior volume sufficient to accommodate only a single article to be sterilized.