Dilation-drug delivery catheter

• US 5,415,636 A
• Filed: 04/13/1994
• Issued: 05/16/1995
• Est. Priority Date: 04/13/1994
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Schneider Electric SE
• Inventors: Forman, Michael R.
• Primary Examiner(s): MCDERMOTT, CORRINE MARIE
• Application Number:
  US08/227,254
• Time in Patent Office: 398 Days
• Field of Search: 604/43, 604/96, 604/101, 604/102, 604/264-266, 604/280, 606/192, 606/194
• US Class Current: 604/101.03
• CPC Class Codes: A61M 2025/0175 having telescopic features, interengaging nestable members movable in relations to one another
• CPC Class Codes: A61M 2025/1015 having two or more independently movable balloons where the distance between the balloons can be adjusted, e.g. two balloon catheters concentric to each other forming an adjustable multiple balloon catheter system
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1079 having radio-opaque markers in the region of the balloon
• CPC Class Codes: A61M 25/1006 Balloons formed between concentric tubes
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

A dilation-drug delivery catheter comprises a dilation portion for dilating a stenosis and a drug delivery portion for delivering antithrombolytic, antiproliferative, or any other type of medication, to the dilation site. The drug delivery portion of the catheter is located within the dilation portion, which can be retracted to reveal the drug delivery portion, after dilation. Occlusion balloons are preferably provided on the drug delivery portion to isolate the dilation site during drug delivery.

Claims

1. A dilation-drug delivery catheter comprising:

a dilation portion comprising an outer catheter shaft, a dilation balloon attached to the outer catheter shaft, the outer catheter shaft comprising a dilation lumen for providing inflation fluid to the dilation balloon and a central lumen;

a drug delivery portion located at least in part within the central lumen, the drug delivery portion comprising an inner catheter shaft having a distal end and at least one drug delivery port in the distal end, the inner catheter shaft defining a drug delivery lumen for providing a drug to the drug delivery port, the drug delivery port being located in a portion of the inner catheter shaft lying within the central lumen,

a first occlusion balloon attached to the inner catheter shaft distal to the drug delivery port and an inflation lumen in fluid communication with the first occlusion balloon, and

a second occlusion balloon attached to the inner catheter shaft proximal to the drug delivery port,

wherein the dilation portion is adapted to retract from the distal end of the drug delivery portion to reveal the first occlusion balloon and the drug delivery port.

2. The dilation-drug delivery catheter of claim 1, wherein the inflation lumen is in fluid communication with the first and second occlusion balloons.

3. The dilation-drug delivery catheter of claim 1 wherein there are a plurality of drug delivery ports, at least some of which lie within the central lumen prior to the dilation portion being retracted.

4. The dilation-drug delivery catheter of claim 1 further comprising a lubricous layer between a wall of the central lumen and the inner catheter shaft.

5. The dilation-drug delivery catheter of claim 1 wherein the occlusion balloons comprise inflatable plastic tubes.

6. The dilation-drug delivery catheter of claim 1 wherein the occlusion balloons are blow molded.

7. A dilation-drug delivery catheter comprising (a) a dilation portion comprising a catheter shaft, a dilation balloon attached to the catheter shaft, a dilation lumen for providing dilation fluid to the dilation balloon and a central lumen;

and (b) a drug delivery portion located at least in part within the central lumen and comprising a catheter shaft comprising an inflation lumen and a drug delivery lumen, wherein the distal end of the drug delivery portion comprises a pair of occlusion balloons in fluid communication with the inflation lumen and a plurality of drug delivery ports between the occlusion balloons, the drug delivery ports being in fluid communication with the drug delivery lumen;

wherein the portions are adapted to move with respect to each other to assume a dilation position wherein the distal end of the drug delivery portion is located at least in part within the dilation portion, and a drug delivery position wherein the dilation portion is retracted to reveal the occlusion balloons and the drug delivery ports.

8. A dilation-drug delivery catheter comprising:

an outer catheter shaft, a dilation balloon bonded to the catheter shaft, the catheter shaft having an outer wall and an inner wall defining a lumen for providing dilation fluid to the dilation balloon, the inner wall further defining a central lumen,

an inner catheter shaft having a distal end and comprising a pair of occlusion balloons at its distal end, a lumen in fluid communication with the occlusion balloons to provide inflation fluid to the occlusion balloons, a plurality of drug delivery ports between the occlusion balloons, a lumen in fluid communication with the drug delivery ports to provide drugs to the ports, and a guide wire lumen,

wherein at least a portion of the distal end of the inner catheter shaft lies within the central lumen, and the outer catheter shaft can be moved with respect to the inner catheter shaft to reveal the distal end of the inner catheter shaft.

9. The dilation-drug delivery catheter of claim 8 wherein all of the drug delivery ports lie within the central lumen.

10. The dilation-drug delivery catheter of claim 8, wherein the inner catheter shaft further comprises perfusion passages proximal to the occlusion balloons, the perfusion passages being in fluid communication with the guide wire lumen.