System for estimating target velocity from pulse echoes in response to their correspondence with predetermined delay trajectories corresponding to different distinct velocities

• US 5,419,331 A
• Filed: 02/10/1994
• Issued: 05/30/1995
• Est. Priority Date: 02/10/1994
• Status: Expired due to Fees

• Current Assignee: University of Rochester
• Original Assignee: University of Rochester
• Inventors: Alam, Sheikh K., Parker, Kevin J.
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US08/194,233
• Time in Patent Office: 474 Days
• Field of Search: 128/653.1, 128/660.01, 128/661.02, 128/661.08, 128/661.09, 128/661.10, 73/597, 364/424.01, 364/424.02, 364/424.07
• US Class Current: 600/454
• CPC Class Codes: G01S 15/582 using transmission of interrupted pulse-modulated waves and based upon the Doppler effect resulting from movement of targets

Abstract

In order to avoid the use of complex transform and correlation techniques for estimating the velocity of a target from which ultrasonic RF bursts are received as return echoes, the time of occurrence of successive returns are compared with a plurality of delay trajectories each representing a different target velocity. The trajectory with which the returns match with minimum variance, or maximum likelihood of being in time coincidence, provides an estimate of the velocity of the target. In different embodiments the RF return, the envelope of the return or the quadrature components thereof are processed to determine to which delay trajectory they are most proximal. The search for the delay trajectory is called a "butterfly search" in two dimensions (slow time or transmitted pulse repetition periods and fast time or range). Each butterfly line corresponds to a distinct linear velocity. The criterion that a signal corresponding to the returns should be equal in amplitude at all points along the correct trajectory may be used for envelope and RF signals. The use of the quadrature components is preferred in noisy environments, such as where the target is the scatterers in blood flow and blood flow velocity is to be determined. In the embodiment using the quadrature components, each butterfly line is searched for corresponding normalized likelihood ratio maxima, since such maxima occur on the correct butterfly line. The butterfly search can be implemented with less computation complexity than correlation or transform operations heretofore used for blood flow velocity estimation, and with fewer repeat pulses, and the results are more accurate in the presence of noise.

Claims

1. The method of estimating the velocity of a target from repetitive echoes received in response to transmission of a plurality of repetitive pulses of propagating signals which comprises the steps of

a. translating said echoes into a series of successive outputs which occur in time relationship dependent upon a set of preselected target trajectories,

b. searching for correspondence between the time relationship of said outputs and a plurality of expected time relationships each representing a different preselected target velocity, and

c. selecting the one of said preselected velocities wherein said correspondence is greatest as the estimated velocity of said target.

2. The method according to claim 1 wherein said translating step includes the step of receiving said echoes and providing outputs in the form of RF signal bursts for each of said echoes.

3. The method according to claim 2 wherein said searching step is carried out by sampling each of said RF signal bursts at a plurality of different series of times characterized by different time delay relationships between the times in each series, each time delay relationship corresponding to a different estimate of the velocity of said target, to provide a plurality of sets of samples each corresponding to a different target velocity,

detecting the amplitudes of the samples in each of said sets, and

said selecting step is carried out by detecting the one of said sets in which the samples are in a relationship representing minimum variance in the amplitudes of the samples thereof, the velocity corresponding to said set exhibiting said minimum variance relationship and being the estimate of the velocity of said target.

4. The method according to claim 3 wherein said minimum variance relationship is obtained by detecting the minimum sum of the absolute difference in amplitude of each sample in each of said sets.

5. The method according to claim 3 wherein said minimum variance relationship is the minimum variation in amplitude of said envelopes in each set from a mean amplitude for that set.

6. The method according to claim 1 wherein said translating step includes the step of receiving said echoes and detecting the envelopes thereof to provide said outputs.

7. The method according to claim 6 wherein said searching step is carried out by sampling each of said envelopes in different series of times, the times in each series being in a different time delay relationship to provide a plurality of sets of samples each corresponding to a different estimate of the velocity of the target,

detecting the amplitudes of the samples in each of said sets, and

said selecting step is carried out by detecting the one of said sets in which the samples are in a relationship representing minimum variance in the amplitudes of the samples thereof, the velocity corresponding to said set exhibiting said minimum variance relationship being the estimate of the velocity of said target.

8. The method according to claim 7 wherein said minimum variance relationship is the minimum variation in amplitude of said envelopes in each set from a mean amplitude for that set.

9. The method according to claim 8 wherein said outputs are in a form ##EQU34## where s(n,t) is the output for each echo and n is an index corresponding to the order of each of said outputs in said series, v₀ is the velocity of the target, T is the pulse repetition period of the repetitive pulses of ultrasonic signals which are transmitted, t is time, ω

₀ is the angular frequency of the ultrasonic signals, r(t) is the envelope of the transmitted pulses, φ

₀ is a phase term depending upon the distance (range) of the target from the point at which said pulses are transmitted when the first of said pulses in said series is transmitted, and 2 is a factor for the round trip time between transmission of each of the pulses of ultrasonic signals in each of said series and the reception of the echo in response thereto

, and in discrete time relationship where i is each sample index and f_f is the sampling frequency ##EQU35## and the envelopes of each of said outputs, s(n,t) in each series of n outputs is ##EQU36## where A is a constant, and which in discrete time representation is ##EQU37## and the series of times in which each of said samples is sampled separated in time by Δ

t where ##EQU38## and the butterfly line with this sampling produces an output e_Bv [n] which has a variance var (e_Bv [n]) being minimal along one of a plurality of lines of different slopes corresponding to v_-p - - - v₀ - - - v_p in co-ordinates of n and t where n is spaced by intervals corresponding in time to T, said one of said plurality of lines corresponding to v₀ where v₀ is the target velocity, the velocity of the target is estimated by finding the minimum of var (e_Bv [n]), ##EQU39## where var (e_Bv [n]) is the variance on the one of said lines for target velocity v.

10. The method according to claim 7 wherein said minimum variance relationship is obtained by detecting the minimum sum of the absolute difference in amplitude of each sample in each of said sets.

11. The method according to claim 1 wherein said translating step includes the step of translating each of said outputs into quadrature related components thereof, and providing output signals which vary in accordance with these quadrature related components.

12. The method according to claim 11 wherein said searching step is carried out by searching signals representing said quadrature components, and providing from said searching step a plurality of outputs representing the likelihood of each of said signals being in each of said plurality of time relationships, and said selecting step is carried out by selecting the velocity for the time relationship providing the maximum likelihood as the estimated target velocity.

13. The method according to claim 11 wherein the combination of the quadrature components are in the form of a complex envelope ##EQU40## where n is an index corresponding to the order of each of said outputs in said series, t is time, T is the pulse repetition period of the repetitive pulses of ultrasonic signals which are transmitted, v₀ is the actual velocity of the target, ω

₀ is the angular frequency of the RF ultrasonic signals, φ

₀ is a phase term depended upon the distance of the target from the point the signal pulses are transmitted, 2 is a factor for the round trip time between transmission of each of the transmitted signal pulses and the reception of the echoes in response thereto, r(t) is the envelope of the transmitted pulses, and in discrete time representation i is each sample index and f_f is the sampling frequency ##EQU41## the time difference between the times of sampling of the complex envelope in each series of samples is ##EQU42## where v is a discrete velocity v_-p - - - v_-i, v₀, v₁ - - - v_p, the complex envelope of each series of samples is given by ##EQU43## where τ

₀ is the time between the transmission and reception of the corresponding echo for the first ultrasonic pulse signal in said series of ultrasonic pulse signals and v is the velocity corresponding to each line, and

said maximum correspondence is the maximum likelihood ratio L(v) for the samples in one of said series which in normalized form is ##EQU44## L(v) maximizes only at v=v₀, the velocity of the target being estimated by finding the maximum of L(v), ##EQU45##

14. The method according to claim 13 wherein the mean velocity of the target is represented as the following weighted mean ##EQU46## wherein each series of samples is ##EQU47## from the general discrete form ##EQU48##

15. The method of detecting the velocity of a transcutaneous target selected from the group consisting of movement of tissue, organs and blood flow, from ultrasonic echoes received in response to a plurality of repetitive transmissions of ultrasonic pulse signals which comprises the steps of

a. translating said echoes into a plurality of time displaced outputs, which are located in a space having at least two dimensions defined by orthogonal axes one of which is the time of transmission of said ultrasonic pulse signals and the other of which is the time elapsed between transmission of said pulse signals and the reception of said echoes,

b. detecting upon which of a plurality of butterfly lines in an array containing a plurality of said lines, said time displaced outputs are most proximal, each of said lines corresponding to a different target velocity, and

c. providing as an estimate of the velocity of said target the velocity which corresponds to the line of a plurality of lines which is most proximal to said time displaced output.

16. The method according to claim 15 wherein said outputs are obtained by quadrature demodulation as the complex amplitudes of said echoes, and said detecting step is carried out by sampling said outputs at times defined by each of said butterfly lines to provide a series of quadrature samples, and said estimate providing step is carried out by detecting the greatest correspondence between the butterfly line quadrature samples and the expected signal from a target traveling at a velocity represented by the slope of a butterfly line.

17. The method according to claim 16 wherein said greatest correspondence is obtained by computing the effective product of the outputs and a complex signal which correlates therewith when alike, normalized by said outputs, to provide outputs corresponding to the proximity of said outputs to each of said butterfly lines, and then selecting the output of maximum value as being the most proximal to one of said butterfly lines, said one butterfly line having a slope which is an estimate of the velocity of said target.

18. The method according to claim 17 wherein said effective product of the outputs and the complex signal is obtained by a complex processing step wherein the outputs obtained by quadrature demodulation are multiplied by a signal which represents a complex RF exponential.

19. The method according to claim 17 wherein said effective product of the outputs and a complex signal is obtained by a complex processing step wherein signals corresponding to said ultrasonic echoes are passed through a Hilbert transform operator.

20. Apparatus for estimating the velocity of a target from repetitive echoes received in response to transmission of a plurality of repetitive pulses of propagating signals which comprises

means for translating said echoes into a series of successive outputs which occur in time relationship dependent upon a set of preselected target trajectories,

means for searching for correspondence between the time relationship of said outputs and a plurality of expected time relationships each representing a different preselected target velocity, and

means for selecting the one of said preselected velocities wherein said correspondence is greatest as the estimated velocity of said target.

21. The apparatus according to claim 20 wherein said translating means comprises means for receiving said echoes and providing outputs in the form of RF signal bursts for each of said echoes.

22. The apparatus according to claim 21 wherein said searching means comprises means for sampling each of said RF signal bursts at a plurality of different series of times characterized by different time delay relationships between the times in each series, each time delay relationship corresponding to a different estimate of the velocity of said target, to provide a plurality of sets of samples each corresponding to a different target velocity,

means for detecting the amplitudes of the samples in each of said sets, and

said selecting means comprises means for detecting the one of said sets in which the samples are in a relationship representing minimum variance in the amplitudes of the samples thereof, the velocity corresponding to said set exhibiting said minimum variance relationship and being the estimate of the velocity of said target.

23. The apparatus according to claim 22 wherein said minimum variance relationship is obtained by means for detecting the minimum sum of the difference in amplitude of each sample in each of said sets.

24. The apparatus according to claim 22 wherein said minimum variance relationship is the minimum variation in amplitude of said envelopes in each set from a mean amplitude for that set.

25. The apparatus according to claim 20 wherein said translating means comprises means for receiving said echoes, and means for detecting the envelopes of said echoes to provide said outputs.

26. The apparatus according to claim 20 wherein said searching means comprises means for sampling each of said envelopes in different series of times, the times in each series being in a different time delay relationship to provide a plurality of sets of samples each corresponding to a different estimate of the velocity of the target.

means for detecting the amplitudes of the samples in each of said sets, and

said selecting means comprises means for detecting the one of said sets in which the samples are in a relationship representing minimum variance in the amplitudes of the samples thereof, the velocity corresponding to said set exhibiting said minimum amplitude variance relationship being the estimate of the velocity of said target.

27. The apparatus according to claim 26 wherein said minimum variance relationship is the minimum variation in amplitude of said envelopes in each set from a mean amplitude for that set.

28. The apparatus according to claim 27 wherein said minimum variance relationship is obtained by means for detecting the minimum sum of the absolute difference in amplitude of each sample in each of said sets.

29. The apparatus according to claim 27 wherein said outputs are in a form ##EQU49## where s(n,t) is the output for each echo and n is an index corresponding to the order of each of said outputs in said series, v₀ is the velocity of the target, T is the pulse repetition period of the repetitive pulses of ultrasonic signals which are transmitted, t is time, ω

₀ is the angular frequency of the ultrasonic signals, r(t) is the envelope of the transmitted pulses, φ

₀ is a phase term depending upon the distance (range) of the target from the point at which said pulses are transmitted when the first of said pulses in said series is transmitted, and 2 is a factor for the round trip time between transmission of each of the pulses of ultrasonic signals in each of said series and the reception of the echo in response thereto

, and in discrete time relationship where i is each sample index and f_f is the sampling frequency ##EQU50## and the envelopes of each of said outputs, s(n,t) in each series of n outputs is ##EQU51## where A is a constant, and which in discrete time representation is ##EQU52## and the series of times in which each of said samples is sampled separated in time by Δ

t where ##EQU53## and the butterfly line with this sampling produces an output e_Bv [n] which has a variance var(e_Bv [n]) being minimal along one of a plurality of lines of different slope corresponding to v_-p - - - v₀ - - - v_p in coordinates of n and t where n is spaced by intervals corresponding in time to T, said one of said plurality of lines corresponding to v₀ where v₀ is the target velocity, the velocity of the target is estimated by finding the minimum of var(e_Bv [n]), ##EQU54## where var(e_Bv [n]) is the variance on the one of said lines for the velocity v.

30. The apparatus according to claim 20 wherein said translating means comprises means for translating each of said outputs into quadrature related components thereof, and means for providing output signals which vary in accordance with these quadrature related components.

31. The apparatus according to claim 30 wherein said searching means comprises means for searching signals representing said quadrature components, and means for providing from said searching step a plurality of outputs representing the likelihood of each of said signals being in each of said plurality of time relationships, and said selecting means comprises means for selecting the velocity for the time relationship providing the maximum likelihood as the estimated target velocity.

32. The apparatus according to claim 30 wherein the combination of the quadrature components are in the form of a complex envelope ##EQU55## where n is an index corresponding to the order of each of said outputs in said series, t is time, T is the pulse repetition period of the repetitive pulses of ultrasonic signals which are transmitted, v₀ is the actual velocity of the target, ω

₀ is the angular frequency of the ultrasonic RF signals, φ

₀ is a phase term depended upon the distance of the target from the point which the signal pulses are transmitted, 2 is a factor for the round trip time between transmission of each of the transmitted signal pulses and the reception of the echoes in response thereto, r(t) is the envelope of the transmitted pulses, and in discrete time representation i is each sample index and f_f is the sampling frequency ##EQU56## the time difference between the times of sampling of the complex envelope in each series of samples differs by ##EQU57## where v is a discrete velocity v_-p - - - v_-1, v₁ - - - v_p the complex envelope of each series of samples is given by ##EQU58## where τ

₀ is the time between the transmission and reception of the corresponding echo for the first ultrasonic pulse signal in said series of ultrasonic pulse signals and v is the velocity corresponding to each line, and

said maximum correspondence selector is the maximum likelihood ratio L(v) for the samples in one of said series which in normalized form is ##EQU59## wherein each series of samples is ##EQU60## from the general discrete form ##EQU61## and the estimate of the velocity corresponds to the series of samples having the maximum normalized value of L(v) ##EQU62##

33. The apparatus according to claim 32 wherein the mean velocity of the target is represented as ##EQU63##

34. Apparatus for detecting the velocity of a transcutaneous target selected from the group consisting of movement of tissue, organs and blood flow, from ultrasonic echoes received in response to a plurality of repetitive transmissions of ultrasonic pulse signals which comprises

means for translating said echoes into a plurality of time displaced outputs, which are located in a space having at least two dimensions defined by orthogonal axes, one of which is the time of transmission of said ultrasonic pulse signals and the other of which is the time elapsed between transmission of said pulse signals and the reception of said echoes,

means for detecting upon which of a plurality of butterfly lines in an array containing a plurality of said lines said time displaced outputs are most closely proximal, each of said lines corresponding to a different target velocity, and

means for providing as an estimate of the velocity of said target the velocity which corresponds to the line of a plurality of lines which is most proximal to said time displaced outputs.

35. The apparatus according to claim 34 wherein said outputs are obtained by means for quadrature demodulation as the complex amplitudes of said echoes, and said detecting means comprises means for sampling said outputs at times defined by each of said butterfly lines to provide a series of quadrature samples, and said estimate providing means comprises means for detecting greatest correspondence between the butterfly line quadrature samples and the expected signal from a target traveling at a velocity represented by the slope of a butterfly line.

36. The apparatus according to claim 35 wherein said greatest correspondence is obtained by means for computing the effective product of the outputs and a complex signal which correlates therewith when alike, normalized by the said outputs, to provide outputs corresponding to the proximity of said outputs to each of said butterfly lines, and means for selecting the output of maximum value as being the most proximal to one of said butterfly lines, said one butterfly line having a slope which is an estimate of the velocity of said target.

37. The apparatus according to claim 36 wherein said means for computing the effective product comprises means for complex processing wherein the outputs obtained by quadrature demodulation are multiplied by a signal which represents a complex RF operator to provide the time displaced outputs for said sampling means.

38. The apparatus according to claim 36 wherein said means for computing the effective product comprises complex processing means wherein signals corresponding to said echoes are passed through a Hilbert transform operator to provide said time displaced outputs.