Fumaramide siloxane hydrogel compositions

• US 5,420,324 A
• Filed: 08/24/1994
• Issued: 05/30/1995
• Est. Priority Date: 03/15/1993
• Status: Expired due to Term

• Current Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Original Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Inventors: Lai, Yu-Chin, Bambury, Ronald E.
• Primary Examiner(s): Nagumo, Mark
• Application Number:
  US08/295,966
• Time in Patent Office: 279 Days
• Field of Search: 556/419, 564/153, 564/160
• US Class Current: 556/419
• CPC Class Codes: C07F 7/081 comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
• CPC Class Codes: C07F 7/0838 Compounds with one or more Si-O-Si sequences compounds with a ring containing only alternating Si and O atoms, i.e. cyclosilanes C07F7/21
• CPC Class Codes: C08F 290/064 Polymers containing more than one epoxy group per molecule
• CPC Class Codes: C08F 290/068 Polysiloxanes
• CPC Class Codes: C08F 30/08 containing silicon
• CPC Class Codes: C08L 35/00 Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
• CPC Class Codes: C08L 43/04 Homopolymers or copolymers of monomers containing silicon
• CPC Class Codes: G02B 1/043 Contact lenses

Abstract

Fumaramide-containing monomers are disclosed which are especially useful in the preparation of biocompatible devices, especially contact lenses.

Claims

1. Fumaramide-containing monomers represented by the schematic representations:

##STR9## Y₁ and Y₂ are independently O or NR₄ ;

Z₁ and Z₂ are independently OR₃ or NR₄ R₅ ;

R₁, R₂, R₃, R₄ and R₅ are independently H or an alkyl group having 1 to 10 C atoms;

R₆, R₇, R₈, R₉, R₁₀ and R₁₁ are independently hydrogen, or an alkyl-containing group having 1 to 10 C atoms, or fiuoroalkyl-containing group having 1 to 10 C atoms;

R₁₂, R₁₃ and R₁₄ are independently trimethylsiloxy or pentamethyldisiloxanyloxy;

m is 1 to 10;

n is 5 to 100;