Method and apparatus for non-invasive identification of the endocorporeal spatial distribution of the electrical impedance in a subject

• US 5,421,345 A
• Filed: 12/10/1993
• Issued: 06/06/1995
• Est. Priority Date: 12/22/1992
• Status: Expired due to Fees

• Current Assignee: Siemens AG
• Original Assignee: Siemens AG
• Inventors: Reichenberger, Helmut, Lekholm, Anders
• Primary Examiner(s): RIMELL, SAMUEL G
• Application Number:
  US08/164,715
• Time in Patent Office: 543 Days
• Field of Search: 128/644, 128/653.1, 128/660.06, 128/693, 128/723, 128/734, 128/774
• US Class Current: 600/547
• CPC Class Codes: A61B 5/0535 Impedance plethysmography for measuring blood flow A61B5/0295

Abstract

In a method and apparatus for identifying the spatial distribution of electrical impedance within an examination subject, a source of electrical current is electrically connected to at least two feed electrodes which impress a feed current from the source in an examination region of a subject. The resulting magnetic field is measured at points outside the examination region, and an equivalent current density distribution is reconstructed within the examination region from the measured values of the magnetic field by an evaluation unit. A compensation conductor is connected to the current source. The current source delivers a compensation current, which flows in a direction opposite to the feed current, through the compensation conductor loop, so that the magnetic field generated by the feed current in the connecting lines is compensated. The evaluation unit identifies the spatial distribution of the impedance from the equivalent current density distribution. The spatial distribution of the impedance can be portrayed on a display.

Claims

1. An apparatus for identifying the endocorporeal spatial distribution of the electrical impedance in an examination region of a subject, comprising:

an electric current source which generates a feed current;

two feed electrodes respectively connected to said current source by electrical connecting lines which carry said feed current, said connecting lines having a first magnetic field associated therewith due to said feed current carried therein, said feed electrodes being attachable to a subject and forming means for impressing said feed current into an examination region of said subject and causing a distribution of current in said examination region dependent on the electrical impedance distribution in said examination region and the position of said feed electrodes, said distribution of current causing a second magnetic field;

a compensation conductor Iccp connected to said current source;

said current source including means for supplying a compensation current to said compensation conductor Iccp having a direction opposite to said feed current for compensating said first magnetic field;

magnetic field measuring means for obtaining a spatial distribution of a characteristic quantity of said second magnetic field at a plurality of points outside said examination region;

evaluation means, supplied with said spatial distribution of a characteristic quantity, for reconstructing, from said spatial distribution of a characteristic quantity, an equivalent current density distribution in said examination region which would generate a theoretical magnetic field most closely coinciding with said second magnetic field, said evaluation means including means for identifying the spatial distribution of impedance in said examination region from said equivalent current density distribution; and

display means connected to said evaluation means for visually portraying said spatial distribution of impedance.

2. An apparatus as claimed in claim 1 wherein said compensation conductor loop is disposed substantially parallel to said connecting lines and to said distribution of current in said examination region.

3. An apparatus as claimed in claim 1 wherein said connecting lines and said compensation conductor loop are electrically connected in series.

4. An apparatus as claimed in claim 1 wherein said connecting lines and said compensation conductor loop are electrically connected in parallel, and further comprising balancing means electrically connected in said compensation conductor loop for equalizing said feed current and said compensation current in amplitude and phase.

5. An apparatus as claimed in claim 1 further comprising:

potential measuring means, connected to said evaluation means, for measuring a distribution of electrical potential existing at a surface of said examination region caused by said distribution of current impressed in said examination region; and

wherein said means for identifying the spatial distribution of impedance from said distribution of current density in said examination region comprises means for identifying the .spatial distribution of impedance from aid distribution of current density in said examination region and from said distribution of electrical potential at said surface of said examination region.

6. An apparatus as claimed in claim 5 wherein at least one of said feed electrodes is electrically connected to said potential measuring means.

7. An apparatus as claimed in claim 5 wherein said potential measuring means includes potential-measuring electrodes exclusively used by said potential measuring means.

8. An apparatus as claimed in claim 1 wherein at least one of said feed electrodes is annular.

9. An apparatus as claimed in claim 1 further comprising:

control means connected to said current source for triggering said feed current and said compensation current dependent on a periodic activity of said subject.

10. An apparatus as claimed in claim 1 wherein said current source comprises an alternating current source having a frequency in the range of 1 Hz through 1 kHz.

11. An apparatus as claimed in claim 1 wherein said magnetic field measuring means comprises a multi-channel magnetic field measuring means.

12. An apparatus as claimed in claim 1 wherein said feed electrodes have a shape conforming to an upper body region of said subject, and wherein said examination region comprises said upper body region.

13. An apparatus as claimed in claim 1 wherein said feed electrodes have a shape conforming to an extremity of said examination subject, and wherein said examination region comprises said extremity.

14. A method for identifying the endocorporeal spatial distribution of the electrical impedance in an examination region of a subject, comprising the steps of:

generating a feed current carried by electrical connecting lines, said connecting lines having a first magnetic field associated therewith due to said feed current carried therein;

attaching feed electrodes, connected to said connecting lines, to a subject and impressing said feed current into an examination region of said subject and causing a distribution of current in said examination region dependent on the electrical impedance distribution in said examination region and the position of said feed electrodes, said distribution of current causing a second magnetic field;

supplying a compensation current to a compensation conductor loop in a direction opposite to said feed current for compensating said first magnetic field;

obtaining a spatial distribution of a characteristic quantity of said second magnetic field at a plurality of points outside said examination region;

reconstructing, from said spatial distribution of a characteristic quantity, an equivalent current density distribution in said examination region which would generate a theoretical magnetic field most closely coinciding with said second magnetic field;

identifying the spatial distribution of impedance in said examination region from said equivalent current density distribution; and

visually portraying said spatial distribution of impedance.

15. A method as claimed in claim 14 comprising the additional step of disposing said compensation conductor loop substantially parallel to said connecting lines and to said distribution of current in said examination region.

16. A method as claimed in claim 14 comprising the additional step of connecting said connecting lines and said compensation conductor loop in series.

17. A method as claimed in claim 14 comprising the additional step of connecting said connecting lines and said compensation conductor loop in parallel.

18. A method as claimed in claim 14 comprising the additional steps of:

measuring a distribution of electrical potential existing at a surface of said examination region caused by said distribution of current impressed in said examination region; and

identifying the spatial distribution of impedance from a distribution of current density in said examination region and from said distribution of electrical potential at said surface of said examination region.

19. A method as claimed in claim 14 comprising the additional step of:

triggering said feed current and said compensation current dependent on a periodic activity of said subject.

20. A method as claimed in claim 14 wherein the step of attaching said feed electrodes to said subject is further defined by attaching said feed electrodes to an upper body region of said subject, and wherein said examination region comprises said upper body region.

21. A method as claimed in claim 14 wherein the step of attaching said feed electrodes to said subject is further defined by attaching said feed electrodes to an extremity of said examination subject, and wherein said examination region comprises said extremity.