Tissue specimen collection kit

• US 5,424,040 A
• Filed: 07/15/1993
• Issued: 06/13/1995
• Est. Priority Date: 11/09/1992
• Status: Expired due to Fees

• Current Assignee: Ecopath Corporation
• Original Assignee: Bjorn L. Bjornsson
• Inventors: Bjornsson, Bjorn L.
• Primary Examiner(s): Czaja, Donald E.
• Assistant Examiner(s): TRAN, LIEN THUY
• Application Number:
  US08/092,929
• Time in Patent Office: 698 Days
• Field of Search: 425/256, 425/425, 425/435, 425/117, 425/127, 426/514, 426/515, 422/99, 422/101, 422/104, 422/102, 422/61, 436/174, 436/176, 436/808
• US Class Current: 422/536
• CPC Class Codes: A61B 10/0096 Casings for storing test samples A61B10/0038 and A61B10/0045 take precedence; preservation of living parts of the human or animal body A01N1/02; containers for retaining a material to be analysed B01L3/50; containers for enzymology or microbiology C12M1/16; swab-sampler being part of enzymology or microbiology container C12M1/30
• CPC Class Codes: A61B 2050/006 perpendicular to the lid plane, e.g. by a downward movement
• CPC Class Codes: A61B 90/96 using barcodes
• CPC Class Codes: B01L 2300/0858 Side walls
• CPC Class Codes: B01L 3/508 rigid containers not provided for above
• CPC Class Codes: G01N 1/36 Embedding or analogous mounting of samples
• CPC Class Codes: G01N 2001/315 Basket-type carriers for tissues
• CPC Class Codes: Y10T 436/25 including sample preparation
• CPC Class Codes: Y10T 436/2525 Stabilizing or preserving

Abstract

A surgical pathological specimen kit with cassette. The kit includes a surgical cassette for receiving a pathological specimen, a conical guide for guiding the specimen into the cassette, a cylindrical container to house the cassette and conical guide, and a lid to close the cylindrical container and seal the cassette and conical guide from the exterior. The cassette has a permeable concave membrane which eliminates mechanical handling and increases tissue yield for microscopic examination. A bar code tracking or audit system is used to facilitate identification, tracking and storage of specimens and cassettes.

Claims

1. A tissue specimen collection kit comprising:

(a) a tissue cassette for receiving and holding a tissue specimen, said cassette comprising;

(1) a housing said housing having a top face with art opening and a bottom face with an opening and interior and exterior faces between said top face and said bottom face for enclosing said tissue specimen,

(2) a bottom porous membrane which is removably mounted on said opening of said bottom face of said housing for holding said tissue specimen in said housing, said bottom porous membrane protruding below said housing,

(3) a lid for closing the opening of the top face of the housing of said tissue cassette,

(b) a conical guide member for guiding said specimen into said housing of said cassette, said guide member having an open first end and an open second end, said first end of said conical guide member located opposite said second end and having a diameter larger than said second end for guiding said tissue specimen toward said second end, said guide member comprising a cylindrical chamber with interior and exterior faces and said exterior face of said cylindrical chamber designed to engage the interior face of said tissue cassette, such that said tissue cassette is supported on said conical guide member, whereby when said specimen is passed through said open first end and then expelled by force of gravity from said open second end, said specimen will be directed through said cylindrical chamber of said guide member into said housing and onto said bottom porous membrane;

(c) a container with an open top end and a closed bottom end, said container having a compartment with a top open end and with a perimeter larger than the perimeter of said conical guide member and of said tissue cassette so that when the tissue cassette and the conical guide member are joined together they may be inserted into said compartment of said container, said container having a means for removably supporting said guide member on said container such that said guide member is located in said compartment; and

(d) a lid for closing the open top end of said container after said tissue cassette and said conical guide member are inserted into said container.

2. A tissue specimen collection kit as recited in claim 1, wherein said guide member is funnel shaped, wherein said guide member is inserted into said container, and wherein said guide member has a funnel sheath that fits tightly against the container, such that when the guide member and the attached cassette are removed from the container, a relative vacuum is created in the container below the bottom porous membrane, resulting in a drainage of solutions comprising fixatives through the porous membrane back into the container.

3. A tissue specimen collection kit comprising:

(a) a tissue cassette for receiving and holding a tissue specimen, said cassette comprising;

(1) a housing for enclosing said tissue specimen, said housing having a top face with an opening and a bottom face opposite said top face, interior and exterior faces between said top face and said bottom face, said bottom face comprising a first end and, a second end which are horizontal faces and a bottom porous membrane connecting said first end of said housing to said second end of said housing, said bottom porous membrane protruding below joining points of said membrane with said horizontal faces; and

(2) a lid for closing the opening of the top face of the housing of said tissue cassette.

(b) a conical guide member having interior and exterior faces and a circular open first end opposite an open second end, said first end having a protruding flat circular lip around the circumference of said first end which tapers inward toward said second end to guide said tissue specimen toward said second end, said exterior face of said second end designed to engage the interior face of said housing of said tissue cassette, said cassette being removably supported on said guide member so that a specimen is guided by force of gravity and by said guide member into said housing, and onto said bottom porous membrane;

(c) a cylindrical container with a closed bottom end and an open top end, said open top end having an inward projecting boundary to receive said lip of said conical guide member when said conical guide member and said tissue cassette are joined together and then inserted into said container, said container having a compartment with a top open end with a perimeter slightly larger than that of said conical guide member and that of said tissue cassette such that when said conical guide member and said tissue cassette are joined together, the cassette and the guide member can fit tightly in said compartment, said container including a means for removably supporting said guide member in said container; and

(d) a lid for closing the open top end of said cylindrical container after said tissue cassette and said conical guide member are inserted into said cylindrical container.

4. A tissue specimen collection kit for collecting and encasing a tissue specimen, comprising:

(a) a tissue cassette for receiving and holding a tissue specimen, said cassette comprising;

(1) a housing having a top boundary surrounding a top opening and a bottom face with an opening located opposite said top boundary, interior and exterior faces connecting said top boundary to said bottom face,

(2) a flexible, formed bottom porous membrane which is removably mounted on said housing for closing said opening of said bottom face, said bottom porous membrane protruding below said housing,

(3) a lid for closing the top opening of the housing of the cassette,

(b) a guide member having interior and exterior faces, and an open first end opposite an open second end, said first end having a protruding lip around said first end which tapers inward toward said second end to guide said tissue specimen toward said second end, said exterior face of said second end designed to engage the interior face of said housing of said tissue cassette, said cassette being removably supported on said guide member so that a specimen is guided by force of gravity and by said guide member into said housing, and onto said bottom porous membrane;

(c) a container with an open top and a closed bottom end, said open top end having a means for removably supporting said guide member when said guide member and said tissue cassette are first joined together and then inserted into said container, said container having an open top end with a perimeter larger than the perimeter of said guide member and of said tissue cassette such that when said guide member and said tissue cassette are joined together, the cassette and the guide member can fit in said container; and

(d) a lid for closing said open top end of said container after said tissue cassette and said guide member are inserted into said container.

5. A tissue specimen collection kit for collecting and encasing a tissue specimen, comprising:

(a) a tissue cassette for receiving and holding a tissue specimen, said tissue cassette comprising;

(1) a housing for enclosing said tissue specimen, said housing having a top boundary surrounding a top opening and a bottom face located opposite said top boundary, interior and exterior faces connecting said top boundary to said bottom face, said bottom face comprising a first end and a second end which are horizontal faces and a bottom porous membrane, said bottom porous membrane connecting the first end of said housing to the second end of said housing, and said bottom porous membrane protruding below joining points of said membrane with said horizontal faces,

(2) a perforated lid for closing the top opening of the housing of said tissue cassette,

(b) a funnel-shaped guide member having interior and exterior faces and an open first end and an open second end which is opposite said open first end, said open first end being substantially larger than said open second end, said first end having a protruding lip around the perimeter of said first end which gradually tapers inward toward said second end to guide said tissue specimen toward said second end, said exterior face of said second end designed to engage the interior face of said housing of said tissue cassette such that the specimen is guided by said guide member and by force of gravity into said cassette;

(c) a container having an open top end and a closed bottom end, said open top end having a perimeter larger than the perimeter of said guide member and of said tissue cassette such that said container is able to receive and removably support said lip of said guide member when said guide member and said tissue cassette are first joined together and then inserted into said container; and

(d) a lid for closing said open top end of said container after said cassette and said guide member are inserted into said container.

6. A tissue specimen collection kit as recited in claim 5, wherein said container has interior faces, and wherein said guide member has a funnel sheath that fits tightly against the interior faces of the container, such that when removed with attached cassette from the container, it will create a relative vacuum in the container below the bottom porous membrane and cause a drainage of solutions comprising fixatives through the porous membrane back into the container.

7. A tissue specimen collection kit as recited in claim 6, wherein said open first end of the guide member matches any shape that the open top end of the container has and the open second end of the guide member matches any shape that the top boundary of the housing has.

8. A tissue specimen collection kit comprising:

(a) a tissue cassette for receiving and holding a tissue specimen, said cassette comprising;

(1) a housing for enclosing said tissue specimen with a top boundary surrounding a top opening, a bottom boundary surrounding a bottom opening, said bottom boundary located opposite said top boundary, and interior and exterior faces interposed between said top boundary and said bottom boundary,

(2) a flexible, formed bottom porous membrane which is removably mounted on said bottom boundary of said housing for closing said bottom opening of said housing, said bottom porous membrane protruding below said bottom boundary of said housing,

(3) a lid for closing the top opening of the housing of said tissue cassette,

(b) a guide member having interior and exterior faces and a first end with a perimeter and a protruding lip around the perimeter of said first end which tapers inward toward a second end to guide said tissue specimen toward said second end, said exterior face of said second end designed to engage the interior face of said housing of said tissue cassette in a tight fit;

(c) a container art open top end and a closed bottom end, said open top end having a boundary to receive and removably support said protruding lip of said guide member when said guide member and said tissue cassette are first joined together and then inserted into said container; and

(d) a lid for closing the open top end of said container after said tissue cassette and said guide member are inserted into said container.