Device for analyzing the function of a heart

• US 5,427,112 A
• Filed: 04/23/1993
• Issued: 06/27/1995
• Est. Priority Date: 12/18/1992
• Status: Expired due to Term

• Current Assignee: Pacesetter AB
• Original Assignee: Siemens Elema AB
• Inventors: Noren, Kjell, Hoegnelid, Kurt
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US08/051,250
• Time in Patent Office: 795 Days
• Field of Search: 607/18, 607/24, 607/23, 128/699, 128/702, 128/705, 128/700, 128/696, 364/413.06
• US Class Current: 600/515
• CPC Class Codes: A61N 1/36507 controlled by gradient or slope of the heart potential
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

A device for analyzing the function of a heart, containing a measurement unit for generating a first measurement signal related to a first electrical or mechanical heart variable and an evaluation unit for evaluating the measurement signal, further contains a circuitry for generating a parameter signal related to a heart variable, the evaluation unit analyzing the related values for the measurement signal and the parameter signal. The device can be used for detecting a number of functional aberrations, such as bradycardia, tachyarrhythmia, retrograde conduction, ischemia and ectopia, and for controlling pacemakers and defibrillators.

Claims

1. An apparatus for analyzing the function of a heart comprising:

measurement means for measuring a heart variable and for generating a measurement signal related to said heart variable;

parameter signal generator means for generating a parameter signal related to a heart variable, said parameter signal and said measurement signal having related values; and

evaluation means for identifying and analyzing said related values of said measurement signal and said parameter signal and for generating an analysis result indicative of the functioning of said heart by plotting said measurement signal against said parameter signal to obtain a curve having a morphology and a chronological course, and means for analyzing said morphology and chronological course of said curve.

2. An apparatus as claimed in claim 1 wherein said means for generating a parameter signal comprises means for differentiating said measurement signal to obtain a differentiated signal serving as said parameter signal.

3. An apparatus as claimed in claim 1 wherein said means for generating a parameter signal comprises measurement means for measuring a further heart variable and for generating a further measurement signal related to said further heart variable, said further measurement signal serving as said parameter signal.

4. An apparatus as claimed in claim 1 further comprising further measurement means for measuring a further heart variable and for generating a further measurement signal relative to said further heart variable, said measurement signal, said further measurement signal and said parameter signal having related values, and wherein said evaluation means comprises means for identifying and analyzing said related values of said measurement signal, said further measurement signal and said parameter signal and for generating an analysis result indicative of the functioning of said heart.

5. An apparatus as claimed in claim 1 further comprising:

comparator means for continuously comparing said related values for detecting drift of said related values; and

compensation means, supplied with an output from said comparator means, for compensating current related values for any drift identified by said comparator means.

6. An apparatus as claimed in claim 1 further comprising:

means for storing at least one set of said related values respectively associated with a previously obtained measurement signal and a previously obtained parameter signal;

means for respectively comparing said stored related values to current related values respectively associated with a current measurement signal and a current parameter signal for identifying noise in said current related values if a noise change is present in one of said current related values without an equivalent change being present in the other of said current related values; and

means for compensating a current related value in which noise is identified for the noise identified therein.

7. An apparatus as claimed in claim 1 wherein said evaluation unit comprises:

means for plotting said measurement signal against said parameter signal to obtain a curve exhibiting an arc length; and

means for measuring said arc length, said arc length serving as said analysis result indicative of the functioning of said heart.

8. An apparatus as claimed in claim 7 wherein said means for plotting comprises means for plotting said measurement signal against said parameter signal over one cardiac cycle of said heart.

9. An apparatus as claimed in claim 1 wherein said measurement means comprises means for measuring impedance in said heart and for generating an impedance signal serving as said measurement signal.

10. An apparatus as claimed in claim 9 wherein said parameter signal generator means comprises means for differentiating said impedance signal to obtain a differentiated impedance signal, said differentiated impedance signal serving as said parameter signal.

11. An apparatus as claimed in claim 1 wherein said evaluation means comprises means for plotting said measurement signal against said parameter signal to obtain a curve, and area calculator means for calculating an area, substantially enclosed by said curve, the calculation of said area serving as said analysis result indicative of the functioning of said heart.

12. An apparatus as claimed in claim 11 wherein said area calculator means comprises means for calculating an area substantially enclosed by said curve for each cardiac cycle.

13. An apparatus as claimed in claim 1 wherein said evaluation unit comprises means for plotting said measurement signal against said parameter signal to obtain a curve, and distance calculator means for calculating a distance between selected points on said curve, said distance serving as said analysis result indicative of the functioning of said heart.

14. An apparatus as claimed in claim 13 wherein said distance calculator means comprises means for calculating a distance between selected maximum and minimum points on said curve.

15. An apparatus as claimed in claim 1 wherein said evaluation means comprises means for plotting said measurement signal against said parameter signal to obtain a curve, memory means for storing said curve for each cardiac cycle of said heart, and comparator means for comparing said curve to obtain a comparison result, said comparison result serving as said analysis result indicative of the functioning of said heart.

16. An apparatus as claimed in claim 15 wherein said predetermined curve is a curve obtained by said means for plotting said measurement signal against said parameter signal, for a previous cardiac cycle.

17. An apparatus as claimed in claim 15 further comprising means for supplying a programmed curve to said comparator for use as said predetermined curve.

18. An apparatus as claimed in claim 1 wherein said evaluation means comprises memory means for storing the course of said related values over a selected period of time, and comparator means for comparing said stored course of related values with at least one predetermined course to obtain a comparison result, said comparison result serving as said analysis result indicative of the functioning of said heart.

19. An apparatus as claimed in claim 18 wherein said evaluation means further comprises memory means for storing a course of said related values over an earlier selected period of time for use as said predetermined course.

20. An apparatus as claimed in claim 18 further comprising means for supplying a programmed course of related values to said comparator means for use as said predetermined course.

21. An apparatus as claimed in claim 1 wherein said evaluation means comprises memory means for storing a course in a coordinate system of said related values over a selected period of time, and means for identifying a sequence in which said stored course traverses a selected number of areas in said coordinate system, and comparator means for comparing said sequence with a predetermined sequence to obtain a comparison result, said comparison result serving as said analysis result indicative of the functioning of said heart.

22. An apparatus as claimed in claim 21 wherein said evaluation means further comprises memory means for storing a sequence obtained over an earlier selected period of time for use as said predetermined sequence.

23. An apparatus as claimed in claim 21 further comprising means for supplying a programmed sequence to said comparator means for use as said predetermined sequence.

24. An apparatus for analyzing the function of a heart comprising:

measurement means for measuring a heart variable and for generating a measurement signal related to said heart variable;

parameter signal generator means for generating a parameter signal related to a heart variable, said parameter signal and said measurement signal having related values;

evaluation means for identifying and analyzing said related values of said measurement signal and said parameter signal and for generating an analysis result indicative of the functioning of said heart; and

averaging means for continuously calculating an average of at least one of said related values over a predetermined period of time.

25. An apparatus as claimed in claim 24 wherein said evaluation means comprises means for plotting said measurement signal against said parameter signal to obtain a curve having a morphology, and means for analyzing said morphology of said curve.

26. An apparatus as claimed in claim 24 wherein said evaluation means comprises means for plotting said measurement signal against said parameter signal to obtain a curve having a chronological course, and means for analyzing said chronological course of said curve.

27. An apparatus as claimed in claim 24 wherein said evaluation means comprises means for plotting said measurement signal against said parameter signal to obtain a curve having a morphology and a chronological course, and means for analyzing said morphology and chronological course of said curve.

28. An apparatus for analyzing the function of a heart comprising:

measurement means for measuring impedance in a heart for generating an impedance signal;

parameter signal means for generating a parameter signal by differentiating said impedance signal;

means for plotting said impedance signal against said parameter signal to obtain a curve;

arc length calculator means for calculating an arc length of said curve for each cardiac cycle of said heart;

a plurality of comparators to which the calculated arc length is supplied, each comparator comparing the calculated arc length to a respectively different predetermined arc length and each comparator generating an output signal if the calculated arc length exceeds the respective predetermined arc length; and

computer means for determining whether said heart is hemodynamically stable based on the outputs of said comparators.