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Nanocrystalline magnetic iron oxide particles-method for preparation and use in medical diagnostics and therapy

  • US 5,427,767 A
  • Filed: 05/13/1992
  • Issued: 06/27/1995
  • Est. Priority Date: 05/28/1991
  • Status: Expired due to Term
First Claim
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1. Nanocrystalline magnetic particles consisting of a magnetic iron oxide core of FE3 O4, gamma-Fe2 O3 or mixtures thereof and a chemisorbed coating on this core, wherein composition of the coating material of natural or synthetic glycosaminoglycans and/or derivatives thereof with molecular weights of 500 Da to 250,000 Da combined, optionally covalently cross-linked by appropriate cross-linking agents and/or modified by specific additives.

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