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Mesoscale sperm handling devices

  • US 5,427,946 A
  • Filed: 01/21/1994
  • Issued: 06/27/1995
  • Est. Priority Date: 05/01/1992
  • Status: Expired due to Term
First Claim
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1. A device for the in vitro fertilization of an egg, the device comprising:

  • a solid substrate microfabricated to define;

    a plurality of flow systems, each said flow system comprising;

    an egg nesting chamber;

    a sperm inlet port; and

    an elongate channel of mesoscale cross-sectional dimension, communicating between said egg nesting chamber and said sperm inlet port, which permits competitive sperm migration from said inlet port to said nesting chamber for egg fertilization; and

    an egg disposed within each said nesting chamber.

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