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Biodegradable bursting release system

  • US 5,429,822 A
  • Filed: 03/13/1992
  • Issued: 07/04/1995
  • Est. Priority Date: 03/13/1992
  • Status: Expired due to Term
First Claim
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1. A biodegradable multiphasic delivery system, comprising at least one biodegradable, biocompatible bursting unit, said bursting unit comprising a polymer membrane encapsulating a core material, said core material comprising a predetermined quantity of at least one substance that reacts with water to form a predetermined amount of gas, said polymer membrane permitting a predetermined volume of water, from an environment into which said bursting unit is placed, to enter said bursting unit to react with said at least one substance to form said predetermined amount of gas to cause said bursting unit to rupture, thereby releasing said core material in a single pulse from said bursting unit into said environment.

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