Medication infusion pump with fluoropolymer valve seat

• US 5,433,710 A
• Filed: 06/24/1994
• Issued: 07/18/1995
• Est. Priority Date: 03/16/1993
• Status: Expired due to Fees

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Minimed, Inc. (Medtronic Plc)
• Inventors: VanAntwerp, William P., Indravudh, Virote
• Primary Examiner(s): WEISS, JOHN
• Application Number:
  US08/265,507
• Time in Patent Office: 389 Days
• Field of Search: 604/891.1, 604/892.1, 604/131, 604/151, 604/152, 604/9, 137/359, 137/364
• US Class Current: 604/152
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/14216 Reciprocating piston type
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: Y10T 137/6977 Escutcheon type support
• CPC Class Codes: Y10T 137/6995 Valve and meter wells

Abstract

A medication infusion pump is provided for use in the programmable delivery of a selected medication to a patient, wherein the pump includes a fluoropolymer valve seat engageable with a nonmetallic valve member. The fluoropolymer valve seat defines a substantially inert and nonadherent surface to prevent accumulation of medication deposits thereon. Such deposits are believed to occur as a result of shear denaturation and/or precipitation in the vicinity of the valve seat, in response to relatively high compression forces applied to the medication as the valve member opens and closes. The fluoropolymer valve seat provides a surface which is particularly nonadherent to protein based medications, such as insulin.

Claims

1. A medication infusion pump, comprising:

a housing defining a medication chamber for receiving and storing a supply of a selected medication; and

a pump mechanism for delivering the selected medication in a controlled manner from said medication chamber to a patient, said pump mechanism including a valve having a valve member movable between open and closed positions relative to a valve seat, and spring means for applying a biasing force to said valve member to normally retain said valve member against said valve seat in said closed position, said valve member and said valve seat being formed from nonmetallic and substantially inert materials defining substantially nonadherent surfaces in the vicinity of said valve seat to prevent accumulation of medication deposits on said valve seat.

2. A medication infusion pump as defined in claim 1, wherein said valve member is formed from an elastomer material, and wherein said valve seat includes a valve seat surface formed from a material from the group consisting of fluoropolymer materials, chloropolymer materials, chlorofluoropolymer materials, copolymers, fluorosilicone acrylate, fluoroepoxy materials, and ultra-high molecular weight polyethylenes or polypropylenes.

3. A medication infusion pump as defined in claim 2, wherein said valve member is formed from a silicone elastomer.

4. A medication infusion pump as defined in claim 2, wherein said valve seat comprises a ferrule base having a fluoropolymer cap mounted thereon, said cap defining said valve seat surface.

5. A medication infusion pump as defined in claim 4, wherein said cap is press-fit mounted onto said ferrule base.

6. A medication infusion pump as defined in claim 4, wherein said cap comprises a coating applied to said ferrule base.

7. A medication infusion pump as defined in claim 4, wherein said ferrule base has an annular groove formed therein, said cap comprising an annular ring seated within said groove.

8. A medication infusion pump as defined in claim 4, wherein said ferrule base is formed from a titanium material.

9. A medication infusion pump as defined in claim 4, including means for retaining said cap on said ferrule base.

10. In a medication infusion pump for delivering a selected medication in a controlled manner to a patient, a valve comprising:

a valve member and a valve seat adapted for relative movement between a closed position with said valve member engaging said valve seat and an open position with said valve member spaced from said valve seat to permit flow of medication through said valve seat; and

spring means for applying a biasing force to normally retain said valve member in engagement with said valve seat;

said valve member and said valve seat having engageable surfaces formed from nonmetallic and substantially inert materials which are substantially nonadherent to medication deposits.

11. An infusion pump valve as defined in claim 10, wherein said valve member is formed from an elastomer material, and wherein said valve seat includes a valve seat surface formed from a material from the group consisting of fluoropolymer materials, chloropolymer materials, chlorofluoropolymer materials, copolymers, fluorosilicone acrylate, fluoroepoxy materials, and ultra-high molecular weight polyethylenes or polypropylenes.

12. An infusion pump valve as defined in claim 11, wherein said valve seat comprises a ferrule base having a fluoropolymer cap mounted thereon, said cap defining said valve seat surface.

13. An infusion pump valve as defined in claim 12, wherein said cap is press-fit mounted onto said ferrule base.

14. An infusion pump valve as defined in claim 12, wherein said cap comprises a coating applied to said ferrule base.

15. An infusion pump valve as defined in claim 12, wherein said ferrule base has an annular groove formed therein, said cap comprising an annular ring seated within said groove.

16. In a medication infusion pump for delivering a selected medication in a controlled manner to a patient, a valve comprising:

a valve member formed from a substantially inert resilient elastomer;

a valve seat defining an annular valve seat surface formed from a substantially inert and nonadherent material from the group consisting of fluoropolymer materials, chloropolymer materials, chlorofluoropolymer materials, copolymers, fluorosilicone acrylate, fluoroepoxy materials, and ultra-high molecular weight polyethylenes or polypropylenes, said valve seat defining a medication flow port, and said valve member being movable relative to said valve seat between open and closed positions respectively spaced from and in engagement with said valve seat surface; and

spring means for applying a biasing force to said valve member to normally retain said valve member in said closed position.

17. An infusion pump valve as defined in claim 16, wherein said valve seat comprises a ferrule base having a fluoropolymer cap mounted thereon, said cap defining said valve seat surface.

18. An infusion pump valve as defined in claim 17, wherein said cap is press-fit mounted onto said ferrule base.

19. An infusion pump valve as defined in claim 17, wherein said cap comprises a coating applied to said ferrule base.

20. A medication infusion pump as defined in claim 17, wherein said ferrule base has an annular groove formed therein, said cap comprising an annular ring seated within said groove.

21. A method of delivering a selected medication from a medication infusion pump in a controlled manner to a patient, said method comprising:

storing a supply of a selected medication within a housing defining a medication chamber; and

delivering the selected medication in a controlled manner from said medication chamber to a patient with a pump mechanism, said pump mechanism including a valve having a valve member and a valve seat adapted for relative movement between a closed position with said valve member engaging said valve seat and an open position with said valve member spaced from said valve seat to permit flow of medication through said valve seat, and spring means for applying a biasing force to said valve member for normally retaining said valve member in the closed position, said valve member and said valve seat having engagement surfaces which are formed from nonmetallic and substantially inert materials to prevent accumulation of medication deposits on said valve seat.