Nebulizer

• US 5,435,282 A
• Filed: 05/19/1994
• Issued: 07/25/1995
• Est. Priority Date: 05/19/1994
• Status: Expired due to Term

• Current Assignee: Habley Medical Technology Corporation
• Original Assignee: Habley Medical Technology Corporation
• Inventors: Foster, Clark B., Smedley, William H., Haber, Terry M.
• Primary Examiner(s): Burr, Edgar S.
• Assistant Examiner(s): Deane, Jr., William J.
• Application Number:
  US08/245,876
• Time in Patent Office: 432 Days
• Field of Search: 128/200.13, 128/200.16, 128/200.14, 128/200.15, 128/200.17, 128/200.18, 128/203.12, 128/203.15, 128/203.19, 239/338, 239/102.2, 261/DIG. 48
• US Class Current: 128/200.16
• CPC Class Codes: A61M 15/0065 Inhalators with dosage or measuring devices A61M15/0028 takes precedence; dosage devices incorporated in aerosol cans B65D83/52
• CPC Class Codes: A61M 15/0085 using ultrasonics spraying or atomising liquids using ultrasonic vibrations in general B05B17/06
• CPC Class Codes: A61M 2016/0024 with an on-off output signal, e.g. from a switch
• CPC Class Codes: B05B 11/02 Membranes or pistons acting on the contents inside the container, e.g. follower pistons
• CPC Class Codes: B05B 17/0646 Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
• CPC Class Codes: Y10S 261/48 Sonic vibrators

Abstract

A hand-held inhalation responsive nebuliser by which a nebulised air stream is created for quick and efficient delivery of a fluid medication to the respiratory tract of a patient through the deep lung. The nebuliser includes a normally open electrical switch and a rotatable trigger ring extending laterally across an air flow path through which a supply of non-medicated ambient air is drawn during inhalation by the patient. The ambient air supply drawn through the nebuliser causes the trigger ring to rotate into contact with and close the electrical switch, whereby a piezoelectric disk is energized to vibrate an emitter mesh. A metered volume of fluid medication delivered to the emitter mesh from a pre-filled medication cartridge is accelerated and pulled through the mesh as a fine mist of fluid droplets to form a nebulised medication plume. The nebulised medication plume is mixed in the mouthpiece of the nebuliser with the supply of non-medicated ambient air to create the nebulised air stream.

Claims

1. An inhalation responsive nebuliser surrounded by ambient air and comprising:

a hollow housing having proximal and distal ends and an air flow path extending therebetween;

a mouthpiece attached to the distal end of said housing at which a patient'"'"'s inhalation draws a supply of the ambient air distally through the air flow path of said housing and into said mouthpiece;

an emitter mesh located within said housing and communicating with said mouthpiece;

cartridge means in which to store a fluid medication, said cartridge means including a piston located at one end thereof;

means to deliver a supply of said fluid medication from said cartridge means to said emitter mesh; and

electric drive circuit means including electrical switch means, said electrical switch means responsive to the supply of ambient air drawn through the air flow path of said housing for connecting said drive circuit means to said emitter mesh and causing said emitter mesh to vibrate, whereby the fluid medication delivered to said emitter mesh from said cartridge means passes through said mesh as a mist to be mixed with the supply of ambient air in said mouthpiece.

2. The nebuliser recited in claim 1, in which said electrical switch means includes a pair of normally open electrical contacts and ambient air responsive means extending laterally across said housing in substantially perpendicular alignment with the air flow path thereof, the supply of ambient air drawn distally though said air flow path of said housing displacing said ambient air responsive means so as to close said pair of electrical contacts and connect said electrical drive circuit means to said emitter mesh.

3. The nebuliser recited in claim 2, wherein said ambient air responsive means extending laterally across said housing in substantially perpendicular alignment with said air flow path thereof is a trigger ring surrounding said cartridge means.

4. The nebuliser recited in claim 3, wherein said trigger ring is pivotally connected to said housing, the supply of ambient air drawn distally through said air flow path rotating said trigger ring into physical contact with said pair of electrical contacts to close said contacts and connect said electrical drive circuit to said emitter mesh.

5. The nebuliser recited in claim 1, wherein said electrical drive circuit means also includes an electrically conductive emitter plate having an opening therethrough, said emitter mesh seated on said emitter plate to cover said opening.

6. The nebuliser recited in claim 5, wherein said electrical drive circuit means also includes a piezoelectric disk attached to said emitter plate, said electrical drive circuit means causing said piezoelectric disk to vibrate, which vibration is transferred to said emitter mesh by way of said emitter plate.

7. The nebuliser recited in claim 6, wherein said electrical drive circuit means also includes upper and lower electrically conductive holding posts for applying pressure to and retaining said emitter plate for vibration therebetween.

8. The nebuliser recited in claim 1, wherein said means to deliver a supply of fluid from said cartridge means to said emitter mesh is a needle cannula located in fluid communication with said cartridge means, said nebuliser further comprising fluid deliver valve means positioned between said needle cannula and said emitter mesh to control the delivery of said supply of fluid to said emitter mesh.

9. The nebuliser recited in claim 8, further comprising a dose selection control knob located at the proximal end of said housing and movable distally therethrough, said dose selection control knob connected to said piston, such that a distal movement of said control knob causes a corresponding axial movement of said piston through said medication cartridge for forcing fluid medication into said needle cannula to be expulsed therefrom.

10. The nebuliser recited in claim 8, wherein said fluid delivery valve means includes a flexible membrane having at least one fluid orifice formed therethrough and closed to the passage of said fluid medication, said flexible membrane being distended towards said emitter mesh in response to said fluid medication being expulsed from said needle cannula to open said fluid orifice and enable said supply of fluid medication to be delivered to said emitter mesh.

11. The nebuliser recited in claim 10, further comprising an electrically conductive needle cannula support located in said housing for retaining said needle cannula between said cartridge means and the flexible membrane of said fluid delivery valve means, said membrane seated upon said needle cannula support so that said at least one fluid orifice of said membrane is closed against said support.

12. A nebuliser comprising:

a hollow housing having proximal and distal ends and an air flow path extending therebetween;

a mouthpiece attached to the distal end of said housing at which a patient'"'"'s inhalation draws air distally through the air flow path of said housing and into said mouthpiece;

an emitter mesh located within said housing and communicating with said mouthpiece;

cartridge means in which to store a fluid medication; and

means to deliver a supply of said fluid medication from said cartridge means to said emitter mesh including fluid valve means located between said emitter mesh and said cartridge means, said fluid valve means having a flexible membrane with at least one fluid orifice formed therethrough that is closed to the delivery of said supply of said fluid medication from said cartridge means to said emitter mesh, said flexible membrane being distended towards said emitter mesh in response to said supply of said fluid medication from said cartridge means to thereby open said fluid orifice to the delivery of said supply of fluid medication from said cartridge means to said emitter mesh.

13. The nebuliser recited in claim 12, further comprising electrical drive circuit means including electrical switch means, said electrical switch means responsive to the supply of air drawn through the air flow path of said housing for connecting said drive circuit means to said emitter mesh and causing said emitter mesh to vibrate, whereby the fluid medication delivered to said emitter mesh from said cartridge means passes through said mesh as a mist to be mixed with the supply of air in said mouthpiece.

14. The nebuliser recited in claim 13, wherein said electrical switch means includes a pair of normally open electrical contacts and air responsive means extending laterally across said housing in substantially perpendicular alignment with the air flow path thereof, the supply of air drawn distally though the air flow path of said housing displacing said air responsive means so as to close said pair of electrical contacts and connect said electrical drive circuit means to said emitter mesh.

15. The nebuliser recited in claim 14, wherein said air responsive means extending laterally across said housing in substantially perpendicular alignment with said air flow path thereof is a trigger ring surrounding said cartridge means.

16. The nebuliser recited in claim 15, wherein said trigger ring is pivotally connected to said housing, the supply of air drawn distally through said air flow path rotating said trigger ring into physical contact with said pair of electrical contacts to close said contacts and connect said electrical drive circuit means to said emitter mesh.

17. The nebuliser recited in claim 13, wherein said electrical drive circuit means also includes an electrically conductive emitter plate having an opening therethrough and a piezoelectric disk attached to said emitter plate, said emitter mesh seated on said emitter plate to cover said opening, and said electrical drive circuit means causing said piezoelectric disk to vibrate, which vibration is transferred to said emitter mesh by way of said emitter plate.

18. The nebuliser recited in claim 12, wherein said means to deliver a supply of fluid from said cartridge means to said emitter mesh also includes a needle cannula located in fluid communication with said cartridge means, the flexible membrane of said fluid valve means positioned between said needle cannula and said emitter mesh to control the delivery of said supply of fluid to said emitter mesh via said needle cannula.

19. The nebuliser recited in claim 18, further comprising a piston moving axially through said cartridge means and a dose selection control knob located at the proximal end of said housing and moving distally therethrough, said dose selection control knob connected to said piston such that a distal movement of said control knob causes a corresponding axial movement of said piston through said cartridge means for forcing fluid medication into said needle cannula from said cartridge means.

20. The nebuliser recited in claim 18, further comprising an electrically conductive needle cannula support located in said housing for retaining said needle cannula between said cartridge means and the flexible membrane of said fluid valve means, said membrane seated upon said needle cannula support so that said at least one fluid orifice of said membrane is closed against said support.