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Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells

  • US 5,437,994 A
  • Filed: 12/10/1993
  • Issued: 08/01/1995
  • Est. Priority Date: 06/15/1989
  • Status: Expired due to Term
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1. A method for obtaining ex vivo human stem cell division comprising culturing a human hematopoietic stem cell composition in a liquid culture medium which is replaced at a rate of from 50 to 100% daily replacement, while maintaining said culture under physiologically acceptable conditions.

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