Parachlorometaxylenol antimicrobial formulation

• US 5,439,681 A
• Filed: 06/07/1993
• Issued: 08/08/1995
• Est. Priority Date: 03/25/1991
• Status: Expired due to Term

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Khan, Mohammad A., Hoang, Minh Q.
• Primary Examiner(s): Webman, Edward J.
• Application Number:
  US08/072,658
• Time in Patent Office: 792 Days
• Field of Search: 424/400, 424/405
• US Class Current: 424/400
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/04 Dispersions, emulsions, suspoemulsions, suspension concentrates or gels foams A01N25/16
• CPC Class Codes: A01N 25/30 characterised by the surfactants
• CPC Class Codes: A01N 31/08 Oxygen or sulfur directly attached to an aromatic ring system
• CPC Class Codes: C11D 1/22 derived from aromatic compounds
• CPC Class Codes: C11D 1/29 Sulfates of polyoxyalkylene ethers
• CPC Class Codes: C11D 1/345 Phosphates or phosphites
• CPC Class Codes: C11D 1/72 Ethers of polyoxyalkylene glycols
• CPC Class Codes: C11D 1/83 Mixtures of non-ionic with anionic compounds
• CPC Class Codes: C11D 3/48 Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions

Abstract

A unique antimicrobial composition comprising parachlorometaxylenol, nonionic surfactant, anionic surfactant, foam builder, moisturizer and/or emollient thickener and an acid to adjust to pH. The composition is useful in providing antimicrobial effectiveness in surgical scrub applications with mildness characteristics.

Claims

1. An antimicrobial composition comprising:

(a) parachlorometaxylenol in an amount from 1.5 to about 3.5 weight percent of the total composition;

(b) poly(oxypropylene) poly-(oxyethylene) in an amount from 1.0 to 6.0 weight percent of the total composition;

(c) an ammonium salt of sulfated nonylphenoxypoly(ethyleneoxy) ethanol in an amount from 2.0 to 12.0 weight percent of the total composition;

(d) ammonium lauryl sulfosuccinate in an amount from about 2.0 to about 12.0 weight percent of the total composition;

(e) lanolin in an amount from about 5.0 to about 15.0 weight percent of the total composition;

(f) cellulose, 2-hydroxyethyl ether in an amount from about 0.1 to about 1.0 weight percent of the total composition;

(g) an acid to adjust the pH in the range of from about 4 to about 6; and

(h) the balance water.