Pacemaker with vasovagal syncope detection

• US 5,441,525 A
• Filed: 05/20/1994
• Issued: 08/15/1995
• Est. Priority Date: 05/20/1994
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Hess, Michael F., Shelton, Michael B., Riff, Kenneth M.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Getzow, Scott M.
• Application Number:
  US08/246,903
• Time in Patent Office: 452 Days
• Field of Search: 607/6, 607/9, 607/18, 607/23, 607/24, 128/706
• US Class Current: 607/23
• CPC Class Codes: A61N 1/365 controlled by a physiological parameter, e.g. heart potential evoked response A61N1/371
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585

Abstract

A rate-responsive cardiac pacemaker implements a novel scheme which detects incipient vasovagal syncope (or other episodes caused by a vasodepressive or cardioinhibitory disorder) when a) the heart rate drops below a programmable minimum size, and b) the rate after said drop is below a programmable maximum drop ending rate. The pacemaker implements a stability and intervention procedure upon the detection of an episode, in which it ignores transient drops in rate, and paces at a predetermined high rate if the drops are stable. The pacemaker then gradually reduces the pacing rate over a predetermined time to the pre-episodic level. A sleep disable feature disables the vasovagal syncope detection and therapy features during the patient'"'"'s sleeping hours to reduce or eliminate false positive responses.

Claims

1. A cardiac pacemaker for detecting the onset of a cardioinhibitory episode comprising:

heart rate drop determination means for determining the size of a drop in heart rate;

minimum rate drop storage means for storing a programmable minimum rate drop;

minimum rate storage means for storing a programmable maximum drop ending rate;

comparator means coupled to said heart rate drop determination means, said minimum rate drop storage means, and said minimum rate storage means for comparing the size of said drop in rate to said minimum rate drop, and for comparing an ending rate to said maximum drop ending rate, said ending rate being defined as the heart rate at the time said rate drop is determined; and

cardioinhibitory indication means coupled to said comparator means for indicating the occurrence of a cardioinhibitory episode when said rate drop exceeds said minimum rate drop and said ending rate is below said maximum drop ending rate.

2. The cardiac pacemaker in claim 1 wherein said cardioinhibitory indication means further comprises consecutive cycle counter means for enabling said cardioinhibitory indication means to indicate the occurrence of a cardioinhibitory episode only after counting a predetermined number of consecutive cardiac cycles in which said rate drop exceeds said minimum rate drop and said ending rate is below said maximum drop ending rate.

3. The cardiac pacemaker in claim 1 further comprising:

sleep period determination means for determining at least one sleep period; and

disable means coupled to said cardioinhibitory indication means for disabling said cardioinhibitory indication means during a determined sleep period.

4. The cardiac pacemaker in claim 3 wherein said sleep period determination means further comprises clock means for keeping track of a patient'"'"'s diurnal cycle.

5. A cardioinhibitory detection method adapted for use in a cardiac pacemaker for detecting the onset of cardioinhibitory episode comprising the steps of:

determining the size of a drop in heart rate;

storing a programmable minimum rate drop;

storing a programmable maximum drop ending rate; and

comparing the size of said drop in rate to said minimum rate drop, and for comparing an ending rate to said maximum drop ending rate, said ending rate being defined as the heart rate at the time said rate drop is determined; and

indicating the occurrence of a cardioinhibitory episode when said rate drop exceeds said minimum rate drop and said ending rate is below said maximum drop ending rate.

6. The cardioinhibitory detection method in claim 5 further comprising the steps of:

counting the number of consecutive cardiac cycles in which said rate drop exceeds said minimum rate drop and said ending rate is below said maximum drop ending rate; and

enabling the indication of the occurrence of a cardioinhibitory episode only when said number of consecutive cycles at least equals a predetermined number.

7. The cardiac pacing method in claim 5 further comprising the steps of:

determining at least one sleep period; and

disabling said cardioinhibitory indication step during a determined sleep period.

8. The cardiac pacing method in claim 7 wherein the sleep period determining step further comprises keeping track of a patient'"'"'s diurnal cycle.

9. A cardiac pacemaker for detecting the onset of a vasovagal syncope episode comprising:

heart rate drop determination means for determining the size of a drop in heart rate;

minimum rate drop storage means for storing a programmable minimum rate drop;

minimum rate storage means for storing a programmable maximum drop ending rate;

comparator means coupled to said heart rate drop determination means, said minimum rate drop storage means, and said minimum rate storage means for comparing the size of said drop in rate to said minimum rate drop, and for comparing an ending rate to said maximum drop ending rate, said ending rate being defined as the heart rate at the time said rate drop is determined; and

vasovagal syncope indication means coupled to said comparator means for indicating the occurrence of a vasovagal syncope episode when said rate drop exceeds said minimum rate drop and said ending rate is below said maximum drop ending rate.

10. The cardiac pacemaker in claim 9 wherein said vasovagal syncope indication means further comprises consecutive cycle counter means for enabling said vasovagal syncope indication means to indicate the occurrence of a vasovagal syncope episode only after counting a predetermined number of consecutive cardiac cycles in which said rate drop exceeds said minimum rate drop and said ending rate is below said maximum drop ending rate.

11. The cardiac pacemaker in claim 9 further comprising:

sleep period determination means for determining at least one sleep period; and

disable means coupled to said vasovagal syncope indication means for disabling said vasovagal syncope indication means during a determined sleep period.

12. The cardiac pacemaker in claim 11 wherein said sleep period determination means further comprises clock means for keeping track of a patient'"'"'s diurnal cycle.

13. A vasovagal syncope detection method adapted for use in a cardiac pacemaker for detecting the onset of vasovagal syncope episode comprising the steps of:

determining the size of a drop in heart rate;

storing a programmable minimum rate drop;

storing a programmable maximum drop ending rate; and

comparing the size of said drop in rate to said minimum rate drop, and for comparing an ending rate to said maximum drop ending rate, said ending rate being defined as the heart rate at the time said rate drop is determined; and

indicating the occurrence of a vasovagal syncope episode when said rate drop exceeds said minimum rate drop and said ending rate is below said maximum drop ending rate.

14. The vasovagal syncope detection method in claim 13 further comprising the steps of:

counting the number of consecutive cardiac cycles in which said rate drop exceeds said minimum rate drop and said ending rate is below said maximum drop ending rate; and

enabling the indication of the occurrence of a vasovagal syncope episode only when said number of consecutive cycles at least equals a predetermined number.

15. The cardiac pacing method in claim 13 further comprising the steps of:

determining at least one sleep period; and

disabling said vasovagal syncope indication step during a determined sleep period.

16. The cardiac pacing method in claim 15 wherein the sleep period determining step further comprises keeping track of a patient'"'"'s diurnal cycle.