Mechanical positioner for magnetic resonance guided ultrasound therapy

• US 5,443,068 A
• Filed: 09/26/1994
• Issued: 08/22/1995
• Est. Priority Date: 09/26/1994
• Status: Expired due to Term

• Current Assignee: InSightec Ltd.
• Original Assignee: General Electric Company
• Inventors: Abeling, Walter R., Rohling, Kenneth W., Cline, Harvey E.
• Primary Examiner(s): ZELE, KRISTA MICHELLE
• Application Number:
  US08/312,247
• Time in Patent Office: 330 Days
• Field of Search: 128/653.2, 128/653.5, 128/660.03, 601/2-4, 607/96, 607/97
• US Class Current: 600/411
• CPC Class Codes: A61B 2017/00911 for fields applied by a magnetic resonance imaging system
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: G01R 33/4804 Spatially selective measurement of temperature or pH
• CPC Class Codes: G01R 33/4814 MR combined with ultrasound

Abstract

A positioner for a magnetic resonance (MR) surgery system which positions a focal point of an ultrasound transducer to selectively destroys tissue in a region within a patient. The positioning means moves an ultrasound transducer under the control of an operator. Mechanical threaded shafts and slides act as screw drives causing several connected slides to move the ultrasound transducer in three dimensions. Expanding shafts are connected between a fixed point on a housing and the actuating point of the threaded shafts. Two of the expanding shafts employ universal joints allowing the shafts to rotate as they follow the slides. The third expanding shaft need only expand but the relative angle between its attachment points does not change, thereby eliminating the need for universal joints. An MR imaging system employing a temperature sensitive pulse sequence, creates an image of the tissue and the region being heated to allow the operator to adjust the position of the ultrasonic transducer so as to direct ultrasonic energy to the appropriate location.

Claims

1. A magnetic resonance (MR) focused heat system for positioning a focal point of an energy transducer within a subject, comprising:

a) an energy transducer for Concentrating energy at a focal point;

b) a subject interface located between the energy transducer and said subject, for facilitating energy to pass from the energy transducer to said subject;

c) a transducer plate constructed of an MR compatible material, for carrying the energy transducer;

d) a first slide constructed of an MR compatible material, having a first threaded shaft slideably connected to the transducer plate such that the transducer plate slides relative to the first slide when the first threaded shaft is rotated;

e) a second slide constructed of an MR compatible material, having a second threaded shaft slideably connected to the first slide such that the first slide slides relative to the second slide when the second threaded shaft is rotated;

f) a base plate constructed of an MR compatible material, having a third threaded shaft slideably connected to the second slide such that the second slide slides relative to the base plate when the third threaded shaft is rotated;

g) a first actuating means for causing rotation of the first threaded shaft;

h) a second actuating means for causing rotation of the second threaded shaft; and

i) a third actuating means for causing rotation of the third threaded shaft thereby causing the energy transducer to be positioned in three dimensions.

2. The MR focused heat system of claim 1 wherein at least one of the first, second and third actuating means comprises:

a) expanding shafts connected to the threaded shafts, capable of expanding or contracting to move with the threaded shafts and for providing torsional forces to the threaded shafts; and

b) motor means functionally coupled to the expanding shafts for applying torsional forces to the threaded shafts.

3. The MR focused heat system of claim 1 wherein the subject interface comprises:

a) an ultrasound transparent membrane in contact with the subject;

b) an ultrasound transparent medium in contact with the membrane and situated between the membrane and the transducer, for conducting ultrasound energy from the transducer to the membrane.

4. The MR focused heat system of claim 1 further comprising:

a) an input device allowing the operator to choose a three-dimensional position for the energy transducer; and

b) a control workstation coupled to the input device, the first, second, and third actuating means for converting the chosen three-dimensional position to a position signal, and for driving the first, second and third actuating means to move said energy transducer to the chosen three-dimensional position.