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Microelectrodes and their use in a cathodic electrochemical current arrangement with telemetric application

  • US 5,443,710 A
  • Filed: 11/18/1992
  • Issued: 08/22/1995
  • Est. Priority Date: 05/09/1984
  • Status: Expired due to Term
First Claim
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1. A microelectrode for inserting in vivo, in situ or in vitro into a warm-blooded or cold-blooded animal brain or body, or extra-corporeally of said animal brain or body and measuring, in vivo, in situ, or in vitro, intracellular and/or extracellular concentrations and/or release and/or reuptake inhibition of one or more biogenic chemicals, comprising, a mixture of graphite, oil and at least one compound selected from the group consisting of complex lipids and simple lipids and salts thereof and wherein the complex lipid is selected from the group consisting of acylglycerols, phosphoglycerides, sphingolipids, glycolipids, lipoproteins and waxes and the simple lipid is selected from the group consisting of terpenes, steroids and prostaglandins, said graphite, said oil, and the compound being present in said microelectrode in a ratio of graphite, in weight in grams, oil, in volume, in cubic centimeters, and compound, in weight in grams, of 0.15 to 7.5:

  • 0.1 to 5.0;

    0.01 to 0.5, respectively, the diameter of the microelectrode ranging from about 0.001 μ

    m to about 10 mm, and said oil has a specific gravity from 0.5 to 2.

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