Boron difluoride compounds useful in photodynamic therapy and production of laser light
First Claim
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1. A compound selected from the group consisting of:
- (a) ##STR50## wherein R is H or lower alkyl;
(b) ##STR51## wherein X is CH or N, Y is CH or N, and R is lower alkyl, where at least one of X and Y is N; and
(c) α
,α
'"'"'-dipyridylmethane-BF2.
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Abstract
A new group of fluorescent organic compounds having a variety of uses are described. They are especially useful as dye compounds in dye laser systems, and as photochemical agents in the treatment of diseased tissues using photodynamic therapy techniques. The compounds include a tri-cyclic compound having the following structure: ##STR1## Preferably R1 -R5 ═R9 -R12 ═C; R7 ═B; R6 and R8 ═N; R14 ═lower n-alkyl or an electron withdrawing group such as CN- ; R16 and R19 are independently selected from the group consisting of lower n-alkyl, a sulfate or an acid or salt thereof, or hydrogen; and R20 ═R21 ═F. Other compounds include compounds of the formula ##STR2##
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Citations
6 Claims
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1. A compound selected from the group consisting of:
-
(a) ##STR50## wherein R is H or lower alkyl;
(b) ##STR51## wherein X is CH or N, Y is CH or N, and R is lower alkyl, where at least one of X and Y is N; and(c) α
,α
'"'"'-dipyridylmethane-BF2. - View Dependent Claims (2, 3, 4)
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5. An imidazomethene-BF2 complex according to the formula ##STR54## wherein R1 and R4 are H or lower alkyl and R2 and R3 are CH3 ;
- or R1 -R4 are lower alkyl.
- View Dependent Claims (6)
Specification