System and method for rapid vascular drug delivery

• US 5,451,210 A
• Filed: 12/17/1993
• Issued: 09/19/1995
• Est. Priority Date: 04/29/1991
• Status: Expired due to Term

• Current Assignee: Board of Regents of the University of Texas System (University of Texas System), LifeQuest Medical, Inc. (Wave Sync Corp.)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System), LifeQuest Medical, Inc. (Wave Sync Corp.)
• Inventors: Spoon, Herbert H., Miller, Larry J., Kramer, George C., Zamorano, Ruben G., Jenkinson, Joel P., Collette, David J.
• Primary Examiner(s): Hirsch, Paul J.
• Application Number:
  US08/168,823
• Time in Patent Office: 641 Days
• Field of Search: 604/136, 604/137
• US Class Current: 604/137
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/3247 Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/315 Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/3291 Shafts with additional lateral openings
• CPC Class Codes: A61N 1/0575 with drug delivery

Abstract

A rapid vascular drug delivery device, system and method is provided having a releasibly extending and retracting needle necessary for injecting and withdrawing fluid into and from a physiological or non-physiological cavity. Accordingly, the needle can be releasibly extended with sufficient momentum at a point of impact to penetrate a hard substance such as bone. The needle is slideably placed within an aperture configured at the forward end of a main housing, wherein a trigger needle can be arranged proximate to the forward end in order to detect tissue thickness or bone depth necessary for ensuring accurate placement of the bone-piercing needle within the bone marrow. The needle can receive fluids interspersed by parallel-placed or series-placed fluid containers configured within the main housing. Thus, more than two dissimilar types of fluids or medicants can be pre-loaded into the device and delivered to the subject in order to enhance dissemination of, for example, a resuscitating drug deep within and throughout the bone marrow.

Claims

1. A device for inserting a bone-piercing needle port into bone, comprising:

a main housing which includes an aperture at a front end of said main housing;

a trigger needle having a forward end and a rear end, wherein said rear end is coupled to a trigger release mechanism mounted upon said main housing and said forward end is adapted during use to penetrate soft tissue and activate said trigger release mechanism upon bearing against a bone underlying said soft tissue; and

a bone-piercing needle configured within said main housing, wherein said bone-piercing needle is coupled to said trigger release mechanism to releasibly extend through said aperture and into said bone during activation of the trigger release mechanism.

2. The device as recited in claim 1, wherein said bone-piercing needle is adapted to releasibly extend with sufficient momentum at the point of impact to penetrate bone and reside partially within a bone marrow cavity of said bone.

3. The device as recited in claim 1, wherein said bone-piercing needle comprises a bore and at least one orifice extending into said bore from the side of the bone-piercing needle.

4. The device as recited in claim 3, wherein said orifice is configured at one end of said bone-piercing needle in fluid communication with a bone marrow cavity of said bone.