Probe for MRI imaging and spectroscopy particularly in the cervical region

• US 5,451,232 A
• Filed: 10/05/1993
• Issued: 09/19/1995
• Est. Priority Date: 10/07/1991
• Status: Expired due to Term

• Current Assignee: Medrad Incorporated (Bayer AG), Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Original Assignee: Medrad Incorporated (Bayer AG), Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Inventors: Schnall, Mitchell, Kresel, Herbert Y., Milestone, Barton, Rhinehart, Edward J., Lenkinski, Robert E.
• Primary Examiner(s): ZELE, KRISTA MICHELLE
• Application Number:
  US08/132,152
• Time in Patent Office: 714 Days
• Field of Search: 128/653.2, 128/653.5, 128/772, 128/778, 606/191-194, 606/197, 604/55, 604/96, 604/97, 604/104
• US Class Current: 606/192
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence
• CPC Class Codes: B82Y 15/00 Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• CPC Class Codes: G01R 33/285 Invasive instruments, e.g. catheters or biopsy needles, specially adapted for tracking, guiding or visualization by NMR
• CPC Class Codes: G01R 33/34084 implantable coils or coils being geometrically adaptable to the sample, e.g. flexible coils or coils comprising mutually movable parts

Abstract

An insertable intracavity probe for use in magnetic resonance imaging of an area of interest in a relatively inaccessible region of the body particularly the cervix is disclosed. The probe has an inflatable balloon structure with an internal pickup coil carried at the distal end of a shaft for rectal insertion of the coil and an inflatable anti-migration cuff to hold the probe in position and prevent outward migration thereof during a procedure. The balloon structure has an outer balloon shaped to facilitate insertion and accommodation of the coil to areas of the anatomy adjacent the cervix. Internally, the balloon structure has an inflatable balloon which can be used to adjust the shape of the coil to accommodate uniquely shaped anatomical areas.

Claims

1. An insertable intracavity probe for use in magnetic resonance imaging of a region of interest within a cavity of a patient, said probe comprising:

an elongate shaft having proximate and distal ends; and

an expansible RF receiving structure on the distal end of the shaft, the expansible structure having height and width dimensions both perpendicular to the shaft axis and comprising;

(a) an external expansible membrane mounted on the shaft;

(b) an expansion means mounted on the distal end of the shaft within the volume enclosed by the external membrane, the expansion means causing expansion of the external membrane in opposed directions perpendicular to the shaft and substantially confined within a single plane defined by the width dimension; and

inflation means for inflating the expansible RF structure into an expanded state; and

wherein the width dimension of the expansible structure is substantially greater than the height dimension in the expanded state.

2. A probe as defined in claim 1 wherein the expansion means comprises a second expansible membrane constructed of a non-stretchable flexible material.

3. A probe as defined in claim 1 wherein the external expansible membrane is constructed of an elastic material.

4. A probe as defined in claim 1 wherein the expansion means is configured as two closed loops.

5. A probe as defined in claim 1 wherein the expansion means is configured to form longitudinal arm portions.

6. An insertable intracavity probe for use in magnetic resonance imaging of a region of interest within a cavity of a patient comprising an elongate shaft having a proximal end, a distal end, a handle on the proximal end of the shaft, and a balloon structure on the distal end of the shaft, the balloon structure including an outer balloon, a pickup coil in the outer balloon, the coil having an electrical lead for connecting the coil to an interface network, inflatable internal balloon means connected to the coil within the outer balloon for selectively adjusting the shape of the coil by inflation and deflation of the balloon means, and inflation means for inflating and deflating the balloon means, wherein the balloon means comprises opposed balloon arms each extending along opposed side portions of the coil respectively for expanding the coil laterally by inflation of the balloon arms and contracting the coil laterally by deflation of the balloon arms, and wherein the shaft has opposed lateral extensions on which the respective balloon arms are mounted through openings in the respective arms, and the inflation means includes airline lumen branches in the respective extensions.

7. A probe as defined in claim 6 wherein the airline lumen branches extend outwardly from a common airline lumen formed through the shaft.

8. An insertable intracavity probe for use in magnetic resonance imaging of a region of interest within a cavity of a patient comprising an elongate shaft having a proximal end, a distal end, a handle on the proximal end of the shaft, and a balloon structure on the distal end of the shaft, the balloon structure including an outer balloon, a pickup coil in the outer balloon, the coil having an electrical lead for connecting the coil to an interface network, inflatable internal balloon means connected to the coil within the outer balloon for selectively adjusting the shape of the coil by inflation and deflation of the balloon means, and inflation means for inflating and deflating the balloon means, wherein the balloon means comprises opposed balloon arms each extending along opposed side portions of the coil respectively for expanding the coil laterally by inflation of the balloon arms and contracting the coil laterally by deflation of the balloon arms, and wherein the balloon arms are connected to the respective side portions of the coil by adhesive means.

9. An insertable intracavity probe for use in magnetic resonance imaging of a region of interest within a cavity of a patient comprising an elongate shaft having a proximal end, a distal end, a handle on the proximal end of the shaft, and a balloon structure on the distal end of the shaft, the balloon structure including an outer balloon, a pickup coil in the outer balloon, the coil having an electrical lead for connecting the coil to an interface network, inflatable internal balloon means connected to the coil within the outer balloon for selectively adjusting the shape of the coil by inflation and deflation of the balloon means, and inflation means for inflating and deflating the balloon means, wherein the balloon means comprises opposed balloon arms each extending along opposed side portions of the coil respectively for expanding the coil laterally by inflation of the balloon arms and contracting the coil laterally by deflation of the balloon arms, and wherein the balloon means is of a horseshoe-like shape.