×

Molecular imaging

  • US 5,453,199 A
  • Filed: 05/20/1994
  • Issued: 09/26/1995
  • Est. Priority Date: 03/30/1992
  • Status: Expired due to Fees
First Claim
Patent Images

1. In the method of separating solutes in a mixture comprising passing the mixture through a matrix which differentially binds individual solutes in said mixture and then desorbing solutes bound to said matrix, the improvement comprising:

  • providing a matrix comprising,a solid material defining a binding surface comprising a coating adhered to a surface of said solid material and defining a multiplicity of regions which selectively bind a preselected organic molecule having a plurality of ionizable groups spaced about a molecular surface thereof,each said region comprising a plurality of charged moieties bonded to said binding surface and disposed in spaced-apart relation within said region in a mirror image and charge inverse of at least a subset of said ionizable groups whereby said regions bind by spatially matched electrostatic attraction to the molecular surface of said preselected organic molecule preferentially to other molecules,wherein said preselected organic molecule is a target solute in said mixture; and

    passing said mixture through said matrix into contact with said surface to preferentially bind said target solute to said binding regions.

View all claims
  • 0 Assignments
Timeline View
Assignment View
    ×
    ×