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Cartridge assembly for a lyophilized compound forming a disposable portion of an injector pen and method for same

  • US 5,454,786 A
  • Filed: 03/28/1994
  • Issued: 10/03/1995
  • Est. Priority Date: 03/15/1993
  • Status: Expired due to Term
First Claim
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1. A method for reconstituting a lyophilized compound, comprising:

  • providing a lyophilized compound contained within an interior space defined by an inner wall of a cartridge having an inlet at one end thereof and a plunger at an opposite end thereof;

    attaching a connector to the inlet end of the cartridge, the connector having a neck portion coaxial with a longitudinal axis of the cartridge and a tubular first portion connected to said neck portion, said first portion having an interior space and defining an axis along a longitudinal length thereof, the axis of the first portion forming an oblique angle relative to the axis of the cartridge;

    placing a syringe having a needle and containing the diluent into the interior space of the first portion, such that the needle is oriented toward the inner wall of the cartridge; and

    injecting a diluent from the syringe into the cartridge via the inlet such that the diluent impinges on and runs down the inner wall of the cartridge before contacting the lyophilized compound whereby foaming of the compound is prevented.

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