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Porous balloon for selective dilatation and drug delivery

  • US 5,458,568 A
  • Filed: 09/17/1993
  • Issued: 10/17/1995
  • Est. Priority Date: 05/24/1991
  • Status: Expired due to Term
First Claim
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1. A method of delivering a drug to internal body tissue, comprising the steps of:

  • (a) providing a catheter having a non-wetted and controllably permeable porous membrane proximate said distal end of said catheter, said membrane having a predetermined pore size and defining a drug delivery chamber at said distal end of said catheter;

    (b) positioning said drug delivery chamber proximate said internal body tissue;

    (c) wetting said porous membrane with a fluid thereby making said membrane permeable, said fluid having a predetermined surface tension and a predetermined contact angle with the porous membrane; and

    (d) transporting said drug from said delivery chamber to said internal body tissue across said porous membrane.

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